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We narrowed to 863 results for: SOM

Showing: 41 - 60 of 863 results
  1. CRISPR Plasmids - Base Edit

    Type
    Collection
    ...sequence, some base editing systems create a wide spectrum of single-nucleotide variants (somatic hypermutation...
  2. mTOR Pathway

    Type
    Collection
    ...blocks catabolic processes including autophagy and lysosome biogenesis. mTORC2 does not respond to nutrients... enriched in brain S6K Also known as RPS6KB1; Ribosomal protein S6 kinase B1 TSC1/2 TSC1 TSC2 Tuberous...
  3. Zebrafish Plasmid Collection

    Type
    Collection
    ...drug discovery and development. Here we highlight some of the plasmids and tools available at Addgene for...multicellular systems typically relies on genetic markers, somatic mutations, or labeling with fluorescent proteins...
  4. Open Enzyme Collection

    Type
    Collection
    ...H 165510 pOpen-DNA Topoisomerase 1B Vaccinia Virus Vaccinia Virus DNA Topoisomerase 1B 165515 pOpen-EcoRIM...
  5. Viral Production

    Type
    Collection
    ...cultures are inspected for sterility. Transducibility Some viral vectors are tested in vitro and in vivo for...gene expression and/or function. These data are sometimes reported or posted on the material page for the...
  6. TALEN Plasmids and Kits

    Type
    Collection
    ...Assembly via serial ligation. Validated in zebrafish somatic cells. Keith Joung Zhang Lab TALE Toolbox PCR/Golden...labeling specific repetitive DNA sequences in human chromosomes Do you have suggestions for other plasmids that...
  7. COVID-19 Resources

    Type
    Collection
    ...antibody escape mutants and for comprehensive mapping. Some of the following plasmids are available to industry...entry into cells. ( 4 ) Cathepsin L - a cysteine endosomal protease that triggers proteolysis of SARS-CoV...
  8. Plan Your Experiment

    Type
    Collection
    ...and variables for using CRISPR in mammalian cells. Some of the variables include: Species of Cas enzyme ... genotypes within the resulting cell population. Some cells may be wild type due to either (1) a lack ...
  9. Allen Institute for Brain Science AAV Enhancer Collection

    Type
    Collection
    ...Shapovalova N, Shulga L, Sigler AR, Siverts LA, Somasundaram S, Stewart K, Szelenyi E, Tieu M, Trader C, ...Graybuck LT, Hess EE, Mahoney JT, Kojima Y, Ding Y, Somasundaram S, Miller JA, Kalmbach BE, Radaelli C, Gore ...
  10. Penn Vector Core Partnership with Addgene

    Type
    Collection
    ...Penn catalog ID: Based on low demand, production of some viral vectors have been discontinued. See the list...be available) Based on low demand, production of some viral vectors have been discontinued. The following...
  11. Cre-lox system

    Type
    Collection
    ...very useful tool, Cre expression can be toxic in some systems, notably Drosophila. Read Addgene's Blog...Cre T. brucei Cross 33345 pLEW100cre-EP1 Cre Trypanosoma brucei Cross 34564 pMSCVpuro-Cre Cre 5'LTR Retroviral...
  12. CRISPR Plasmids - Cascade-Cas3

    Type
    Collection
    ...Cascade complex to express equally. To combat this, some CRISPR-Cas3 plasmids take an all-in-one approach...
  13. TALEN Engineering

    Type
    Collection
    ... ( Tesson et al., Nat Biotechnol. 2011 ) Human somatic cells ( Miller et al., Nat Biotechnol. 2011 ; Reyon...
  14. AAV Molecular Tools

    Type
    Collection
    ...pAAV-FLEX-EGFPL10a EF1a-driven and Cre-dependent EGFP-tagged ribosomal L10a 5, rg* Heintz , Nectow , Schmidt Neurophysiology...
  15. Mammalian RNAi Tools

    Type
    Collection
    ...Most plasmids are in a lentiviral backbone, with some retroviral and AAV backbone options. Plasmids for...
  16. Retrovirus Plasmids

    Type
    Collection
    ...infection results in long-term transgene expression. Some disadvantages of γ-retroviruses are that they can...
Showing: 41 - 60 of 863 results