A Look Back at One Year of Plasmid Sharing for COVID-19 Research
Type
Blog Post
...SARS-CoV-2 spike pseudotyping, visit the SARS-CoV-2 Pseudotyped Virus collection page.
SARS-CoV-2 detection...of SARS-CoV-2 entry and become upregulated during viral infection.
Expression of SARS-CoV-2 viral proteins... expression of cathepsin S, L, and B. This became a great starting point for SARS-CoV-2 researchers to...labs in over 75 countries.
Figure 1: SARS-CoV-2 proteins and other components. Image from Maya Kostman... protein, variants, and pseudotyping
The SARS-CoV-2 virus depends on its spike protein to bind ACE2, the...of infection and how to interfere with it in a BSL-2 lab instead of a BSL-3 lab. Jesse Bloom’s lab published...reagents for pseudotyping lentivirus with the SARS-CoV-2 spike protein. They deposited the plasmids used for...