...membrane. Cancer Impact Ras is ubiquitously expressed in all cells and all tissues. Ras can activate ... however when mutations occur in the Ras gene it can be stuck in a constitutively active form, constantly... leading to cancer. Constitutively active Ras is the most common oncogene in human cancer, found in around...National Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Color is used...National Laboratory for Cancer Research . Frederick National Laboratory for Cancer Research Return to top...Targeting RAS signalling pathways in cancer therapy. Downward J. Nat Rev Cancer. 2003 Jan;3(1):11-22. PubMed ...active Ras is the most common oncogene in human cancer. Cancer...