We narrowed to 121 results for: ELL
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TypeCollection...Tesson et al., Nat Biotechnol. 2011 ) Human somatic cells ( Miller et al., Nat Biotechnol. 2011 ; Reyon and...., Nat Biotechnol 2012 ) Human pluripotent stem cells ( Hockemeyer et al., Nat Biotechnol. 2011 ) TALE...TALE transcriptional activators in human cells ( Maeder et al., Nat Methods 2013 ) More detailed information...
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Mammalian RNAi Tools
TypeCollection... in therapeutic settings. As a tool in mammalian cell systems, silencing is achieved through the delivery...options. Plasmids for constitutive expression as well as those that allow for conditional (Cre-lox) or...). Origins and mechanisms of miRNAs and siRNAs . Cell, 136 (4), 642–655. PubMed (Link opens in a new window... -
CRISPR Plasmids - C. elegans
TypeCollection...sequence. DSBs are preferentially repaired in the cell by non-homologous end joining (NHEJ), a mechanism...PAM site. When a repair template is present, the cell may repair a DSB using homology-directed repair ...Cas protein and a target-specific gRNA in the same cell at the same time. Single plasmids containing both... -
CRISPR Plasmids - Drosophila
TypeCollection...sequence. DSBs are preferentially repaired in the cell by non-homologous end joining (NHEJ), a mechanism...PAM site. When a repair template is present, the cell may repair a DSB using homology-directed repair ...Cas protein and a target-specific gRNA in the same cell at the same time. Single plasmids containing both... -
CRISPR Plasmids - Yeast
TypeCollection...sequence. DSBs are preferentially repaired in the cell by non-homologous end joining (NHEJ), a mechanism...PAM site. When a repair template is present, the cell may repair a DSB using homology-directed repair ...Cas protein and a target-specific gRNA in the same cell at the same time. Single plasmids containing both... -
Distribution to Industry
TypeCollection...plasmids for detecting GPCR activity in a variety of cell types. Protein Purification Optimization Kit Using...application-specific validation and quality control by Addgene as well as by our trusted partner labs. Learn More ID Recombinant...governs the transfer of biological materials and intellectual property rights, and provides liability protection... -
TALEN Guide
TypeCollection...a typo in the latest draft of your dissertation. Well, that will probably never happen. Yet with transcription...summer of 2011 and has already become the best-selling kit in Addgene’s history. Dr. Keith Joung’s lab.... Targeted gene disruption in somatic zebrafish cells using engineered TALENs. Sander JD, Cade L, Khayter... -
CRISPR Plasmids - Plants
TypeCollection...sequence. DSBs are preferentially repaired in the cell by non-homologous end joining (NHEJ), a mechanism...PAM site. When a repair template is present, the cell may repair a DSB using homology-directed repair ...Cas protein and a target-specific gRNA in the same cell at the same time. Single plasmids containing both... -
Tags and Other Markers
TypeCollection...catalog that target epitope tags and other common cellular proteins. These ready-to-use recombinant monoclonal...application-specific validation and quality control by Addgene as well as by our trusted partner labs. To learn more about... -
Synthetic Biology - Sensing and Signaling
TypeCollection...collection of synthetic biology plasmids related to cell-to-cell communications and environmental sensing. Sensing... -
Fluorescent Protein Guide: Activity Regulation
TypeCollection...Fluorescent Protein Resources: Empty Backbones FRET Subcellular localization Biosensors Optogenetics Background...components or take advantage of existing GFP-lines for cell-specific manipulation. Plasmids Fluorescent Protein... -
KLF Research Plasmids
TypeCollection...Depositing Labs Juan Belmonte Linzhao Cheng Jose Cibelli George Daley Jin-Tang Dong Steven Dowdy Scott Friedman...regulators with diverse roles in processes such as cell proliferation, differentiation, inflammation, metabolism... -
MAPK Plasmids
TypeCollection...Mitogen-activated protein kinases (MAPKs), also known as extracellular signal-regulated kinases (ERKs), are serine/...threonine-specific protein kinases. They regulate diverse cellular programs by acting as an integration point for... -
AAV Viral Preps
TypeCollection... tools that effectively transduce many mammalian cell types. AAV is used in a wide range of experiments...Tetracycline Transactivators, Affinity Purification, Cell Ablation, CRISPR Monosynaptic Neuronal Tracing Rabies... -
CRISPR Plasmids - Double-Strand Break (Cut)
TypeCollection...sequence. DSBs are preferentially repaired in the cell by non-homologous end joining (NHEJ), a mechanism...PAM site. When a repair template is present, the cell may repair a DSB using homology-directed repair ... -
DNA Service - Cloning Grade DNA
TypeCollection...Can I directly transfect cloning grade DNA into cells? Cloning grade DNA is designed for use in cloning...cloning applications. Direct transfection into cells is not recommended. Can I order more than 2 µg of cloning... -
Fluorescent Protein Guide: In Vivo Imaging
TypeCollection...Fluorescent Protein Resources: Empty Backbones FRET Subcellular localization Optogenetics Background In vivo ...stable imaging of protein interactions in living cells and live mice. Proteins for in vivo imaging have... -
Plasmid Collections
TypeCollection...Mammalian RNAi Microbiology Plant Expression Stem Cells Synthetic Biology Tet Inducible Expression Worm ...BioBricks Foundation BRAIN Initiative Collection Cell Migration Consortium Impact of Genomic Variation... -
Chemogenetics Plasmids
TypeCollection...allowing a scientist to control signaling within cells expressing these engineered receptors. Chemogenetic...engineered receptor is coupled to and the specific cell type where the receptor is expressed, these receptors... -
SARS-CoV-2 Pseudotyped Virus
TypeCollection...then be used to infect permissive cells that express ACE2, the cellular receptor for SARS-CoV-2, in a single...