Skip to main content
This website uses cookies to ensure you get the best experience. By continuing to use this site, you agree to the use of cookies.

Please note: Your browser does not support the features used on Addgene's website. You may not be able to create an account or request plasmids through this website until you upgrade your browser. Learn more

Please note: Your browser does not fully support some of the features used on Addgene's website. If you run into any problems registering, depositing, or ordering please contact us at [email protected]. Learn more

Addgene

pAG414GPD-dCas9-VPR Citations (11)

Originally described in: Highly efficient Cas9-mediated transcriptional programming.
Chavez A, Scheiman J, Vora S, Pruitt BW, Tuttle M, P R Iyer E, Lin S, Kiani S, Guzman CD, Wiegand DJ, Ter-Ovanesyan D, Braff JL, Davidsohn N, Housden BE, Perrimon N, Weiss R, Aach J, Collins JJ, Church GM Nat Methods. 2015 Mar 2. doi: 10.1038/nmeth.3312.
PubMed Journal

Articles Citing pAG414GPD-dCas9-VPR

Articles
Engineering Synthetic Gene Circuits in Living Cells with CRISPR Technology. Jusiak B, Cleto S, Perez-Pinera P, Lu TK. Trends Biotechnol. 2016 Jan 22. pii: S0167-7799(15)00274-7. doi: 10.1016/j.tibtech.2015.12.014. PubMed
Benchmarking of TALE- and CRISPR/dCas9-Based Transcriptional Regulators in Mammalian Cells for the Construction of Synthetic Genetic Circuits. Lebar T, Jerala R. ACS Synth Biol. 2016 Oct 21;5(10):1050-1058. Epub 2016 Jun 28. PubMed
Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies. Jensen ED, Ferreira R, Jakociunas T, Arsovska D, Zhang J, Ding L, Smith JD, David F, Nielsen J, Jensen MK, Keasling JD. Microb Cell Fact. 2017 Mar 15;16(1):46. doi: 10.1186/s12934-017-0664-2. PubMed

Associated Plasmids

Delivery of an Artificial Transcription Regulator dCas9-VPR by Extracellular Vesicles for Therapeutic Gene Activation. Lainscek D, Kadunc L, Keber MM, Bratkovic IH, Romih R, Jerala R. ACS Synth Biol. 2018 Dec 21;7(12):2715-2725. doi: 10.1021/acssynbio.8b00192. Epub 2018 Dec 7. PubMed
Hyperosmotic Stress Response Memory is Modulated by Gene Positioning in Yeast. Meriem ZB, Khalil Y, Hersen P, Fabre E. Cells. 2019 Jun 13;8(6). pii: cells8060582. doi: 10.3390/cells8060582. PubMed
CRISPR-mediated activation of biosynthetic gene clusters for bioactive molecule discovery in filamentous fungi. Roux I, Woodcraft C, Hu J, Wolters R, Gilchrist CLM, Chooi YH. ACS Synth Biol. 2020 Jun 11. doi: 10.1021/acssynbio.0c00197. PubMed

Associated Plasmids

A CRISPR activation and interference toolkit for industrial Saccharomyces cerevisiae strain KE6-12. Camara E, Lenitz I, Nygard Y. Sci Rep. 2020 Sep 3;10(1):14605. doi: 10.1038/s41598-020-71648-w. PubMed

Associated Plasmids

CRISPR-based transcriptional activation tool for silent genes in filamentous fungi. Mozsik L, Hoekzema M, de Kok NAW, Bovenberg RAL, Nygard Y, Driessen AJM. Sci Rep. 2021 Jan 13;11(1):1118. doi: 10.1038/s41598-020-80864-3. PubMed

Associated Plasmids

Regulation of protein secretion through chemical regulation of endoplasmic reticulum retention signal cleavage. Praznik A, Fink T, Franko N, Lonzaric J, Bencina M, Jerala N, Plaper T, Roskar S, Jerala R. Nat Commun. 2022 Mar 14;13(1):1323. doi: 10.1038/s41467-022-28971-9. PubMed
Validation of CRISPR activation system in Aedes cells using multicistronic plasmid vectors. Jaiswal V, Varghese SA, Ghosh S. Front Bioeng Biotechnol. 2023 Apr 19;11:1142415. doi: 10.3389/fbioe.2023.1142415. eCollection 2023. PubMed
Regulation of CD19 CAR-T cell activation based on an engineered downstream transcription factor. Lainscek D, Golob-Urbanc A, Mikolic V, Pantovic-Zalig J, Malensek S, Jerala R. Mol Ther Oncolytics. 2023 Apr 26;29:77-90. doi: 10.1016/j.omto.2023.04.005. eCollection 2023 Jun 15. PubMed

If you have published an article using this material, please email us at [email protected] to have your article added to this page.