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Plasmid#11817DepositorInsertCaspase 8 (CASP8 Human)
UseTagsExpressionMammalianMutationPromoterAvailable sinceMay 25, 2006AvailabilityAcademic Institutions and Nonprofits only -
loxP-T2A-Myr-DeadCasp8-ERT2-rox-FNF-loxP-T2A-Myr-Casp8-ERT2-rox
Plasmid#182360PurposeShuttle vector for T2A-Myr-DeadCasp8-ERT2 and T2A-Myr-Casp8-ERT2DepositorInsertMyr-DeadCasp8-ERT2 and Myr-Casp8-ERT2
UseCre/Lox, Mouse Targeting, and Synthetic Biology ;…TagsExpressionMammalianMutationPromoterAvailable sinceMarch 31, 2022AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_CASP8_WT_V5
Plasmid#82999PurposeGateway Donor vector containing CASP8, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.DepositorInsertCASP8 (CASP8 Human)
UseGateway entry vectorTagsExpressionMutationAA 184_191delERSSSLEGinsGEELCGVMTISD; D194R; 196_…PromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
psicheck-2-Casp8
Plasmid#48172Purposecontains Renilla Luciferase gene preceded by an intact (ATG) upstream open reading frame elementDepositorInsert5" UTR of CASP8 (CASP8 Human)
UseLuciferaseTagsExpressionMutationPromoterAvailable sinceOct. 16, 2013AvailabilityAcademic Institutions and Nonprofits only -
pLentiCRISPR-v2 sgCASP8
Plasmid#211519PurposeDeletes CASP8DepositorInsertsgCASP8
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterAvailable sinceJan. 8, 2024AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3-Casp8 C360A
Plasmid#11818DepositorInsertCaspase 8 catalytic mutant (CASP8 Human)
UseTagsHAExpressionMammalianMutationC360APromoterAvailable sinceMay 12, 2006AvailabilityAcademic Institutions and Nonprofits only -
pLVX-opto-mCasp8
Plasmid#208782PurposeInducibly expresses mouse caspase8 fused to light-activatable Cry2DepositorInsertmCherry mCaspase8 Cry2 (Casp8 Mouse)
UseLentiviralTagsCry2 and mCherryExpressionMammalianMutationPromoterAvailable sinceNov. 2, 2023AvailabilityAcademic Institutions and Nonprofits only -
pLC-RFP657-CASP8
Plasmid#75164PurposeLentiCRISPR-RFP657 with sgRNA targeting human Caspase-8DepositorInsertCASP8 sgRNA (CASP8 Human)
UseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterU6Available sinceJune 8, 2016AvailabilityAcademic Institutions and Nonprofits only -
pX459-puro-hCASP8
Plasmid#185378PurposeFor mammalian expression of guide RNA: AAGCAATCTGTCCTTCCTGA that targets human CASP8 (Caspase 8)DepositorInsertCASP8 (CASP8 Human)
UseTagsExpressionMammalianMutationWTPromoterAvailable sinceJune 8, 2022AvailabilityAcademic Institutions and Nonprofits only -
psicheck-2-Casp8-mod
Plasmid#48171Purposecontains Renilla Luciferase gene preceded by a mutated (ATG --> ATT) upstream open reading frame elementDepositorInsert5" UTR of CASP8 (CASP8 Human)
UseLuciferaseTagsExpressionMutationG/T MUTATION IN ATG OF UORFPromoterAvailable sinceOct. 16, 2013AvailabilityAcademic Institutions and Nonprofits only -
pET15b-Casp8 delta DED
Plasmid#11827DepositorInsertCaspase 8 minus Death Effecter Domain (CASP8 Human)
UseTags6xHisExpressionBacterialMutationMinus Death Defecter Domain (aa 1-216)PromoterAvailable sinceMay 12, 2006AvailabilityAcademic Institutions and Nonprofits only -
pET15b-Casp8 delta DED C360A
Plasmid#11828DepositorInsertCaspase 8 minus Death Effecter Domain catalytic mutant (CASP8 Human)
UseTags6xHisExpressionBacterialMutationMinus Death Defecter Domain (aa 1-216), C360APromoterAvailable sinceMay 12, 2006AvailabilityAcademic Institutions and Nonprofits only -
loxP-T2A-Myr-Casp8-ERT2-rox
Plasmid#182362PurposeShuttle vector for T2A-Myr-Casp8-ERT2DepositorInsertloxP-T2A-Myr-Casp8-ERT2-rox
UseCre/Lox and Mouse Targeting; Dre / roxTagsExpressionMammalianMutationPromoterAvailable sinceMarch 31, 2022AvailabilityAcademic Institutions and Nonprofits only -
loxP-T2A-Myr-DeadCasp8-ERT2-rox
Plasmid#182361PurposeShuttle vector for T2A-Myr-DeadCasp8-ERT2DepositorInsertloxP-T2A-Myr-DeadCasp8-ERT2-rox
UseCre/Lox and Mouse Targeting; Dre / roxTagsExpressionMammalianMutationPromoterAvailable sinceMarch 31, 2022AvailabilityAcademic Institutions and Nonprofits only -
LV_EF1a_Caspase8(C360A)-P2A-Hygro_Barcode
Plasmid#170217PurposeBarcoded lentiviral vector to express Caspase8 (C360A) in mammalian cells under control of EF1a promoter. Barcoded for transcript detection in single cell RNA-seqDepositorInsertCASP8 (CASP8 Human)
UseLentiviralTagsV5ExpressionMutationC360APromoterEF1aAvailable sinceSept. 23, 2021AvailabilityAcademic Institutions and Nonprofits only -
Caspase-8 (C360A)-pcw107-V5
Plasmid#64632Purposewhen used to produce lentivirus, express physiological levels of insertDepositorInsertCASP8 (transcript variant B) (CASP8 Human)
UseLentiviralTagsV5ExpressionMutationC360APromoterPGKAvailable sinceMay 12, 2015AvailabilityAcademic Institutions and Nonprofits only -
pCW57.1 blast tBID-flag
Plasmid#211533PurposeExpresses truncated BID upon doxycycline addition to trigger apoptosisDepositorInserttBID-flag (BID Human)
UseRetroviralTagsFLAGExpressionMammalianMutationTruncated (CASP8) form (p15)PromoterAvailable sinceJan. 31, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLVX-opto-hCaspase-8
Plasmid#208786PurposeInducibly expresses human Caspase 8 fused to light-activatable Cry2DepositorInsertCaspase 8 (CASP8 Human)
UseLentiviralTagsCry2 mCherryExpressionMammalianMutationCARD domain is removedPromoterAvailable sinceNov. 2, 2023AvailabilityAcademic Institutions and Nonprofits only -
Fv-hCaspase 8-2A-GFP
Plasmid#82712Purposeexpress human caspase 8 in mammalian cellsDepositorInsertFv-Caspase 8-2A-GFP (CASP8 Human)
UseRetroviralTagsFKBP dimerization domainExpressionMammalianMutationdeleted amino acids 1-215 of caspase 8PromoterLTRAvailable sinceSept. 14, 2016AvailabilityAcademic Institutions and Nonprofits only -
Fv-hCaspase 8 (C/A)-2A-GFP
Plasmid#82713Purposeexpress human caspase 8 in mammalian cellsDepositorInsertFv-Caspase 8 (C/A)-2A-GFP (CASP8 Human)
UseRetroviralTagsFKBP dimerization domainExpressionMammalianMutationdeleted amino acids 1-215 of caspase 8PromoterAvailable sinceNov. 4, 2016AvailabilityAcademic Institutions and Nonprofits only