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Showing: 601 - 650 of 2791 results

  1. pCDNA3.3_CoV2_B.1.1.7

    Plasmid
    #170451
    Purpose
    Express SARS-CoV-2 B.1.1.7 (UK strain / alpha strain) spike protein with an 18aa deletion on the C-terminal tail. Used for SARS2 (UK strain) pseudotyped virus production.
    Depositor
    David Nemazee
    Article
    Yuan et al Science. 2021 Aug 13;373(6556):818-823.
    Insert
    SARS-CoV-2 501V2 spike D18 (S SARS-CoV-2, UK strain (B.1.1.7))
    Use
    Tags
    NA
    Expression
    Mammalian
    Mutation
    HY69-70del, Y144del, N501Y, A570D, D614G, P681H, …
    Promoter
    CMV
    Available since
    May 17, 2021
    Availability
    Academic Institutions and Nonprofits only
    170451-plasmid-map-sequence-id-333038

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  2. pcDNA5-FRT-TO-Nprot-HF_GC3opt

    Plasmid
    #157732
    Purpose
    mammalian expression of C-terminally His8-Flag tagged SARS-CoV-2 N protein under control of a tetracycline-inducible promoter
    Depositor
    David Tollervey
    Article
    Bresson et al Wellcome Open Res. 2020 Nov 3;5:261. doi
    Insert
    Nprot-HF_GC3opt (N SARS-CoV-2)
    Use
    Tags
    His8-Flag
    Expression
    Mammalian
    Mutation
    codon optimized; gene expression was optimized by…
    Promoter
    Available since
    Aug. 10, 2020
    Availability
    Industry, Academic Institutions, and Nonprofits
    157732-plasmid-map-sequence-id-308146

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  3. pcDNA-FRT-TO-FH-Nsp8-Nsp7_GC3opt

    Plasmid
    #157701
    Purpose
    mammalian expression of N-terminally Flag-His8 tagged SARS-CoV-2 Nsp8-Nsp7 fusion protein under control of a tetracycline-inducible promoter
    Depositor
    David Tollervey
    Article
    Bresson et al Wellcome Open Res. 2020 Nov 3;5:261. doi
    Insert
    FH-Nsp8-Nsp7_GC3opt (ORF1ab SARS-CoV-2)
    Use
    Tags
    Flag-His8
    Expression
    Mammalian
    Mutation
    codon optimized; gene expression was optimized by…
    Promoter
    Available since
    Aug. 5, 2020
    Availability
    Industry, Academic Institutions, and Nonprofits
    157701-plasmid-map-sequence-id-307865

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  4. pcDNA3-SARS-CoV-2-S-RBD-8his-N501Y

    Plasmid
    #164845
    Purpose
    Mammalian expression plasmid for RBD of SARS-CoV-2 (N501Y mutant) with 8his tag
    Depositor
    Erik Procko
    Article
    Chan et al Sci Adv. 2021 Feb 17;7(8). pii: 7/8/eabf
    Insert
    Secreted receptor binding domain (RBD; a.a. 333-529) of S protein from SARS-CoV-2 (S SARS coronavirus 2)
    Use
    Tags
    8his tag and HA leader sequence
    Expression
    Mammalian
    Mutation
    Codon-optimized for human cell expression. Has N5…
    Promoter
    CMV
    Available since
    Jan. 26, 2021
    Availability
    Academic Institutions and Nonprofits only
    164845-plasmid-map-sequence-id-322928

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  11. pcDNA3.3_CoV2_D18

    Plasmid
    #170442
    Purpose
    Express SARS-CoV-2 WT spike protein with an 18aa deletion on the C-terminal tail. Used for SARS2 pseudotyped virus production.
    Depositor
    David Nemazee
    Article
    Rogers et al Science. 2020 Aug 21;369(6506):956-963.
    Insert
    SARS-CoV-2 spike D18 (S SARS-CoV-2, USA-WA1/2020 strain)
    Use
    Tags
    NA
    Expression
    Mammalian
    Mutation
    18aa deletion in c-terminal tail
    Promoter
    CMV
    Available since
    July 19, 2021
    Availability
    Academic Institutions and Nonprofits only
    170442-plasmid-map-sequence-id-337888

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  16. pcDNA 3.1-NbON10-NanoLuc

    Plasmid
    #198691
    Purpose
    Expresses anti-SARS-Cov-2 Nucleocapsid nanobody ON10 fused to NanoLuc in HEK293 cell culture
    Depositor
    Gualberto González Sapienza
    Article
    Segovia-de Los Santos et al Front Immunol. 2023 Jul 11;14:1220477. d
    Insert
    anti-SARS-CoV-2 Nucleocapsid nanobody ON10
    Use
    Tags
    6xHis tag, IgK leader sequence, NanoLuc, and twin…
    Expression
    Mammalian
    Mutation
    Promoter
    CMV promoter
    Available since
    Dec. 11, 2024
    Availability
    Academic Institutions and Nonprofits only
    198691-plasmid-map-sequence-id-402807

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  22. pcDNA 3.1(-) rat C/EBP beta (LAP)

    Plasmid
    #12558
    Depositor
    Peter Johnson
    Insert
    CCAAT/Enhancer-binding Protein beta (Cebpb Rat)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 18, 2007
    Availability
    Academic Institutions and Nonprofits only

  23. pcDNA 3.1(-) rat C/EBP beta (LIP)

    Plasmid
    #12562
    Depositor
    Peter Johnson
    Insert
    CCAAT/Enhancer-binding Protein beta LIP (Cebpb Rat)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    Promoter
    Available since
    July 18, 2007
    Availability
    Academic Institutions and Nonprofits only

  28. pcDNA3.1-AntiHer2-LC122-TAG

    Plasmid
    #226839
    Purpose
    Contains trastuzumab with a TAG codon at position 122 of the light chain for ncAA incorporation
    Depositor
    Abhishek Chatterjee
    Article
    Osgood et al Bioconjug Chem. 2024 Apr 17;35(4):457-46
    Inserts
    anti-HER2 light chain
    anti-HER2 heavy chain
    Use
    Affinity Reagent/ Antibody
    Tags
    Expression
    Mammalian
    Mutation
    amino acid 122 of light chain mutated to TAG
    Promoter
    Available since
    Nov. 11, 2024
    Availability
    Academic Institutions and Nonprofits only
    226839-plasmid-map-sequence-id-451751

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  29. pcDNA3.1-AntiHer2-HC121-TAG

    Plasmid
    #226836
    Purpose
    Contains trastuzumab with a TAG codon at position 121 of the heavy chain for ncAA incorporation
    Depositor
    Abhishek Chatterjee
    Article
    Osgood et al Bioconjug Chem. 2024 Apr 17;35(4):457-46
    Inserts
    anti-HER2 light chain
    anti-HER2 heavy chain
    Use
    Affinity Reagent/ Antibody
    Tags
    Expression
    Mammalian
    Mutation
    amino acid 121 of heavy chain mutated to TAG
    Promoter
    Available since
    Nov. 11, 2024
    Availability
    Academic Institutions and Nonprofits only
    226836-plasmid-map-sequence-id-451750

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  30. pcDNA3.1-AntiHer2-HC197-TAG

    Plasmid
    #226838
    Purpose
    Contains trastuzumab with a TAG codon at position 197 of the heavy chain for ncAA incorporation
    Depositor
    Abhishek Chatterjee
    Article
    Osgood et al Bioconjug Chem. 2024 Apr 17;35(4):457-46
    Inserts
    anti-HER2 light chain
    anti-HER2 heavy chain
    Use
    Affinity Reagent/ Antibody
    Tags
    Expression
    Mammalian
    Mutation
    amino acid 197 of heavy chain mutated to TAG
    Promoter
    Available since
    Nov. 11, 2024
    Availability
    Academic Institutions and Nonprofits only
    226838-plasmid-map-sequence-id-451747

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  42. pcDNA3.3_SARS2_Mu

    Plasmid
    #177578
    Purpose
    expressing SARS-CoV-2 B.1.621 (Mu) spike protein for pseudovirus production
    Depositor
    David Nemazee
    Article
    Cho et al Sci Transl Med. 2021 Oct 20;13(616):eabj
    Insert
    Spike (Mu variant) (S SARS-CoV-2)
    Use
    Retroviral
    Tags
    Expression
    Mammalian
    Mutation
    T95I, Y144T, Y145S, R346K, E484K, N501Y, D614G, …
    Promoter
    CMV
    Available since
    Nov. 17, 2021
    Availability
    Academic Institutions and Nonprofits only
    177578-plasmid-map-sequence-id-348240

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  48. pcDNA3.1-IARS2-tb

    Plasmid
    #232340
    Purpose
    Expresses human IARS2 with synonymous mutations (to prevent recognition by siRNA) in mammalian cells
    Depositor
    Quanfu Ma
    Insert
    IARS2 (IARS2 Human)
    Use
    Tags
    Expression
    Mammalian
    Mutation
    5 synonymous mutations in the siRNA (ACUUGCAGUCAU…
    Promoter
    CMV
    Available since
    June 3, 2025
    Availability
    Academic Institutions and Nonprofits only
    232340-plasmid-map-sequence-id-474527

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  50. pcDNA3-sACE2v2.4(732)-IgG1

    Plasmid
    #154106
    Purpose
    Mammalian expression plasmid for dimeric soluble ACE2 high affinity variant 2.4 (IgG1-Fc fusion)
    Depositor
    Erik Procko
    Article
    Chan et al Science. 2020 Sep 4;369(6508):1261-1265.
    Insert
    Angiotensin-converting enzyme 2 (ACE2 Human)
    Use
    Tags
    Fc region of human IgG1
    Expression
    Mammalian
    Mutation
    Extracellular, soluble protease and neck domains …
    Promoter
    CMV
    Available since
    June 24, 2020
    Availability
    Academic Institutions and Nonprofits only
    154106-plasmid-map-sequence-id-301643

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Showing: 601 - 650 of 2791 results