We narrowed to 262 results for: Map2

1. LAMTOR3 gRNA (BRDN0001147910)

   Plasmid

   #77137

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human LAMTOR3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   LAMTOR3 (LAMTOR3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pCDFDuet-MKK6-EE p38alpha

   Plasmid

   #82719

   Purpose

   Expresses constitutively active human MKK6 and murine p38 alpha.

   Depositor

   Kevin Janes

   Article

   Shah et al Mol Cell Proteomics. 2017 Apr;16(4 suppl

   Inserts

   MKK6 (MAP2K6 Human)
   p38alpha (Mapk14 Mouse)
   

   Use

   Tags

   Expression

   Bacterial

   Mutation

   Ser207 to Glu, Thr211 to Glu

   Promoter

   Available since

   Feb. 28, 2019

   Availability

   Academic Institutions and Nonprofits only

3. pCDNA3 Flag MKK7B2Jnk2a2

   Plasmid

   #19727

   Depositor

   Roger Davis

   Article

   Lei et al Mol Cell Biol. 2002 Jul . 22(13):4929-42

   Insert

   pCDNA3 FlagMKK7B2Jnk2a2 (MAPK9, Map2k7 Human, Mouse)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 31, 2009

   Availability

   Academic Institutions and Nonprofits only

4. pcDNA3-MKK1

   Plasmid

   #107973

   Purpose

   expression of MAP Kinase Kinase

   Depositor

   Edwin Krebs

   Article

   Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

   Insert

   MKK1 (MAP2K1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   See depositor comments below.

   Promoter

   CMV

   Available since

   Feb. 20, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pCDNA3 Flag MKK7B2Jnk1a1

   Plasmid

   #19726

   Depositor

   Roger Davis

   Article

   Lei et al Mol Cell Biol. 2002 Jul . 22(13):4929-42

   Insert

   MKK7B2Jnk1a1 (Map2k7, MAPK8 Human, Mouse)
   

   Use

   Tags

   Flag

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 24, 2009

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pBabe-Puro-MEK-DD

   Plasmid

   #15268

   Depositor

   William Hahn

   Article

   Boehm et al Cell. 2007 Jun 15. 129(6):1065-1079.

   Insert

   Map2k1 (Mapk1 Mouse)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   S218D S222D

   Promoter

   Available since

   July 12, 2007

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pcDNA3-MKK1K97A

   Plasmid

   #107974

   Purpose

   expression of a dominant negative MAP Kinase Kinase

   Depositor

   Edwin Krebs

   Article

   Seger et al J Biol Chem. 1994 Oct 14;269(41):25699-7

   Insert

   MKK1 K97A (MAP2K1 Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   dominant negative; see Depositor Comments below

   Promoter

   CMV

   Available since

   Jan. 7, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. NES-EGFP-PH-BTKx2

   Plasmid

   #183652

   Purpose

   PtdIns(3,4,5)P3 biosensor

   Depositor

   Sergio Grinstein

   Article

   Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

   Insert

   BTK (BTK Human, Frog)
   

   Use

   Tags

   X. laevis map2k1.L(32-44)-EGFP

   Expression

   Mammalian

   Mutation

   Amino acids 2-174 and 2-170

   Promoter

   CMV

   Available since

   May 3, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pLX311-GFP-MEKDD

   Plasmid

   #194882

   Purpose

   Expression of dominant negative MEK1

   Depositor

   Sefi Rosenbluh

   Article

   Tuano et al Genome Biol. 2023 Mar 29;24(1):59. doi:

   Insert

   MEKDD (MAP2K1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   S218D, S222D

   Promoter

   E1Fa

   Available since

   March 31, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. NES-mCherry-PH-BTKx2

    Plasmid

    #183654

    Purpose

    PtdIns(3,4,5)P3 biosensor

    Depositor

    Sergio Grinstein

    Article

    Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

    Insert

    BTK (BTK Human, Frog)
    

    Use

    Tags

    X. laevis map2k1.L(32-44)-mCherry

    Expression

    Mammalian

    Mutation

    Amino acids 2-174 and 2-170

    Promoter

    CMV

    Available since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pCDNA3 Flag Jnk1a1MKK7B2

    Plasmid

    #19731

    Depositor

    Roger Davis

    Article

    Lei et al Mol Cell Biol. 2002 Jul . 22(13):4929-42

    Insert

    Jnk1a1MKK7b2 (Map2k7, MAPK8 Human, Mouse)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 24, 2009

    Availability

    Academic Institutions and Nonprofits only

12. NES-EGFP-PH-BTKx1

    Plasmid

    #183651

    Purpose

    PtdIns(3,4,5)P3 biosensor

    Depositor

    Sergio Grinstein

    Article

    Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

    Insert

    BTK (BTK Human, Frog)
    

    Use

    Tags

    X. laevis map2k1.L(32-44)-EGFP

    Expression

    Mammalian

    Mutation

    Amino acids 2-170

    Promoter

    CMV

    Available since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pCMV5-FLAG-MKK6

    Plasmid

    #21582

    Depositor

    John Kyriakis

    Article

    Yuasa et al J Biol Chem. 1998 Aug 28. 273(35):22681-

    Insert

    MKK6 (MAP2K6 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Nov. 24, 2009

    Availability

    Academic Institutions and Nonprofits only

14. pUG36-NES-EGFP-cPHx3

    Plasmid

    #183668

    Purpose

    PtdIns(3,4)P2 biosensor for expression in yeast

    Depositor

    Sergio Grinstein

    Article

    Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

    Insert

    PLEKHA1 (PLEKHA1 Human, Frog)
    

    Use

    Tags

    X. laevis map2k1.L(32-44)-EGFP

    Expression

    Yeast

    Mutation

    Amino acids 169-329 (tandem trimer)

    Promoter

    MET25

    Available since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pUG34-NES-EGFP-cPHx3

    Plasmid

    #183669

    Purpose

    PtdIns(3,4)P2 biosensor for expression in yeast

    Depositor

    Sergio Grinstein

    Article

    Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

    Insert

    PLEKHA1 (PLEKHA1 Human, Frog)
    

    Use

    Tags

    X. laevis map2k1.L(32-44)-EGFP

    Expression

    Yeast

    Mutation

    Amino acids 169-329 (tandem trimer)

    Promoter

    MET25

    Available since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. NES-mCherry-PH-BTKx1

    Plasmid

    #183653

    Purpose

    PtdIns(3,4,5)P3 biosensor

    Depositor

    Sergio Grinstein

    Article

    Walpole et al Nat Cell Biol. 2022 Apr 28. pii: 10.1038

    Insert

    BTK (BTK Human, Frog)
    

    Use

    Tags

    X. laevis map2k1.L(32-44)-mCherry

    Expression

    Mammalian

    Mutation

    Amino acids 2-170

    Promoter

    CMV

    Available since

    May 3, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pCMV5-FLAG-MKK6-K82M

    Plasmid

    #21583

    Depositor

    John Kyriakis

    Article

    Yuasa et al J Biol Chem. 1998 Aug 28. 273(35):22681-

    Insert

    MKK6 (MAP2K6 Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    lysine 82 to methionine

    Promoter

    Available since

    Nov. 24, 2009

    Availability

    Academic Institutions and Nonprofits only

18. Target Accelerator Pan-Cancer Mutant Collection

    Plasmid Kit

    #1000000103

    Purpose

    Panel of cancer alleles that have undergone basic, functional screening; full-length, human clones (454 mutant and 177 corresponding wild-type) in the Gateway cloning system

    Depositor

    Jesse Boehm

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

19. Target Accelerator Genetic Pathway Reference Set

    Plasmid Kit

    #1000000105

    Purpose

    Collection of genes and mutations for reference pathway signatures and phenotypes to compare with those derived from cancer alleles; represent over 25 cellular signaling pathways and processes

    Depositor

    Jesse Boehm

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

20. CCSB-Broad Human Kinase ORF Collection

    Plasmid Kit

    #1000000014

    Purpose

    556 distinct human kinases and kinase-related protein ORFs in a pDONR-223 Entry Gateway vector. All clones are clonal isolates.

    Depositor

    William Hahn, David Root

    Available since

    July 16, 2011

    Availability

    Academic Institutions and Nonprofits only