We narrowed to 4,276 results for: 424

1. dCas9-CBP HAT

   Plasmid

   #179547

   Purpose

   encodes S. pyogenes dCas9 with c-terminal fusion of human CBP HAT domain (aa 1323-1701) driven by EF-1alpha promoter

   Depositor

   Isaac Hilton

   Article

   Wang et al Nucleic Acids Res. 2022 Aug 12;50(14):78

   Insert

   S. pyogenes dCas9 with c-terminal fusion of human CBP HAT domain (aa 1323-1701) (CREBBP Human)
   

   Use

   Lentiviral

   Tags

   Flag Tag

   Expression

   Mammalian

   Mutation

   D10A; H840A in S.pyogenes Cas9

   Promoter

   EF-1alpha

   Available since

   Feb. 18, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCMV-FLAG-CAMK2D-ED

   Plasmid

   #221688

   Purpose

   Mammalian expression of FLAG-tagged human CAMK2D (K43R/D136N)

   Depositor

   Derrick Sek Tong Ong

   Article

   Chuah et al Cell Death Differ. 2023 Aug;30(8):1973-1

   Insert

   CAMK2D (CAMK2D Human)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   K43R, D136N

   Promoter

   Available since

   Aug. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMXS-IRES-BLAST Halo-flag-CAD

   Plasmid

   #188117

   Purpose

   Expresses N-terminal Halo-tagged/C-terminal flag-tagged human CAD in mammalian cells

   Depositor

   Richard Possemato

   Article

   Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

   Insert

   CAD (CAD Human)
   

   Use

   Retroviral

   Tags

   Flag tag and Halo tag

   Expression

   Mammalian

   Mutation

   TCC -> AGT silent mutations at nt439-441 elimi…

   Promoter

   Available since

   Feb. 6, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. DHC1-AID-Clover donor (Neo)

   Plasmid

   #158621

   Purpose

   Donor plasmid for tagging DHC1 with AID-Clover

   Depositor

   Masato Kanemaki

   Article

   Yesbolatova et al Nat Commun. 2020 Nov 11;11(1):5701. doi:

   Insert

   DHC1 (DYNC1H1 Human)
   

   Use

   CRISPR; Tagging donor

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Nov. 12, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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5. pcDNA4/TO/Strep-HA-ZAKalpha_K45A

   Plasmid

   #141194

   Purpose

   Expresses kinase-dead Strep-HA-ZAK alpha in mammalian cells, can be used to make inducible cell line

   Depositor

   Simon Bekker-Jensen

   Article

   Vind et al Mol Cell. 2020 Apr 9. pii: S1097-2765(20

   Insert

   MAP3K20 (MAP3K20 Human)
   

   Use

   Tags

   Strep, HA

   Expression

   Mammalian

   Mutation

   Changed Lysine 45 to Alanine

   Promoter

   CMV

   Available since

   June 5, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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6. Anti-HCN2 [N71/37R]

   Plasmid

   #177567

   Purpose

   Mammalian Expression Plasmid of anti-HCN2 (Rat). Derived from hybridoma N71/37.

   Depositor

   James Trimmer

   Article

   Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

   Insert

   anti-HCN2 (Rattus norvegicus) recombinant mouse monoclonal antibody (Hcn2 Mouse)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Dual CMV

   Available since

   Jan. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDONR223_NRAS_p.Q61L

   Plasmid

   #81674

   Purpose

   Gateway Donor vector containing NRAS, part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, David Root, William Hahn

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   NRAS (NRAS Human)
   

   Use

   Gateway entry vector

   Tags

   Expression

   Mutation

   Q61L

   Promoter

   None

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pDONR223_STAT1_p.Y701F

   Plasmid

   #82183

   Purpose

   Gateway Donor vector containing STAT1 , part of the Target Accelerator Plasmid Collection.

   Depositor

   Jesse Boehm, David Root, William Hahn

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   STAT1 (STAT1 Human)
   

   Use

   Gateway entry vector

   Tags

   Expression

   Mutation

   Y701F

   Promoter

   None

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pIG-721 CTLA4-GFP T124P

   Plasmid

   #186126

   Purpose

   CTLA4 gene knockin with mutation

   Depositor

   Alexander Marson

   Article

   Shy et al Nat Biotechnol. 2022 Aug 25:10.1038/s415

   Insert

   CTLA4 (CTLA4 Human)
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   T124P

   Promoter

   Available since

   July 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA4/TO/Strep-HA-ZAKalpha_deltaSdeltaCTD

    Plasmid

    #141198

    Purpose

    Expresses Strep-HA-ZAKalpha_deltaSdeltaCTD in mammalian cells, can be used to make inducible cell lines

    Depositor

    Simon Bekker-Jensen

    Article

    Vind et al Mol Cell. 2020 Apr 9. pii: S1097-2765(20

    Insert

    MAP3K20 (MAP3K20 Human)
    

    Use

    Tags

    Strep, HA

    Expression

    Mammalian

    Mutation

    deletion of last 27 amino acids and amino acids 6…

    Promoter

    CMV

    Available since

    June 19, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDONR223_ELF1_WT

    Plasmid

    #81883

    Purpose

    Gateway Donor vector containing ELF1 , part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, David Root, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    ELF1 (ELF1 Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    WT

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. pX335 HTT sgRNA-a

    Plasmid

    #87201

    Purpose

    pX335 vector encoding SpCas9n and a chimeric guide RNA targeting exon 1 of HTT

    Depositor

    Mahmoud Pouladi

    Article

    Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

    Insert

    HTT (HTT Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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13. pIG-648 CTLA4int1-CTLA4-GFP-SV40

    Plasmid

    #186123

    Purpose

    CTLA4 gene knockin

    Depositor

    Alexander Marson

    Article

    Shy et al Nat Biotechnol. 2022 Aug 25:10.1038/s415

    Insert

    CTLA4 (CTLA4 Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    WT with GFP sequence

    Promoter

    Available since

    July 28, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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14. pX335 HTT sgRNA-b

    Plasmid

    #87200

    Purpose

    pX335 vector encoding SpCas9n and a chimeric guide RNA targeting 5' UTR of HTT

    Depositor

    Mahmoud Pouladi

    Article

    Xu et al Stem Cell Reports. 2017 Feb 21. pii: S22

    Insert

    HTT (HTT Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    July 28, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHAGE-IDH1-R132L

    Plasmid

    #116411

    Purpose

    Lentiviral expression of IDH1 R132L

    Depositor

    Gordon Mills, Kenneth Scott

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    IDH1 (IDH1 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    R132L

    Promoter

    Available since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. BCL6-GFP Y58A in Artichoke

    Plasmid

    #169936

    Purpose

    Overexpression of BCL6-GFP Y58A mutant fusion

    Depositor

    Benjamin Ebert

    Article

    Slabicki et al Nature. 2020 Dec;588(7836):164-168. doi:

    Insert

    BCL6 Y58A (BCL6 Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mutation

    160R>C

    Promoter

    Available since

    July 28, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. BCL6-GFP R28A in Artichoke

    Plasmid

    #169933

    Purpose

    Overexpression of BCL6-GFP R28A mutant fusion

    Depositor

    Benjamin Ebert

    Article

    Slabicki et al Nature. 2020 Dec;588(7836):164-168. doi:

    Insert

    BCL6 R28A (BCL6 Human)
    

    Use

    Lentiviral

    Tags

    GFP

    Expression

    Mutation

    160R>C

    Promoter

    Available since

    July 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pDONR223_NRAS_p.G12C

    Plasmid

    #81660

    Purpose

    Gateway Donor vector containing NRAS, part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, David Root, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    NRAS (NRAS Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    G12C

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLKO.puro_shGLS

    Plasmid

    #110335

    Purpose

    shGLS (Target CAACTGGCCAAATTCAGTC), silence human GLS gene, puromycin selection

    Depositor

    Sandra Martha Gomes Dias

    Article

    Dias et al Oncogene. 2020 Jan;39(3):690-702. doi: 1

    Insert

    GLS glutaminase (GLS Human, Synthetic)
    

    Use

    Lentiviral and RNAi

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6 (RNA PolIII)

    Available since

    Feb. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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20. pDONR223_NRAS_p.Q61H

    Plasmid

    #81670

    Purpose

    Gateway Donor vector containing NRAS, part of the Target Accelerator Plasmid Collection.

    Depositor

    Jesse Boehm, David Root, William Hahn

    Article

    Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

    Insert

    NRAS (NRAS Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Q61H

    Promoter

    None

    Available since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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