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175,552 results

Showing: 11 - 20 of 175552 results

  2. pCMV-PEmax-P2A-hMLH1dn

    Plasmid
    #174828
    Purpose
    Mammalian expression of SpCas9 PEmax prime editor with P2A-human MLH1dn (codon optimized)
    Depositor
    David Liu
    Article
    Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.
    Insert
    PEmax-P2A-hMLH1dn
    Tags
    SV40 bpNLS and c-Myc NLS
    Expression
    Mammalian
    Mutation
    Detailed in manuscript; deletion of residues 754-…
    Promoter
    CMV
    Available Since
    Oct. 14, 2021
    Availability
    Academic Institutions and Nonprofits only
    174828-plasmid-map-sequence-id-357934

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  3. pAAV-hSyn-DIO-hM4D(Gi)-mCherry (AAV Retrograde)

    Viral Prep
    #44362-AAVrg
    Purpose
    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-DIO-hM4D(Gi)-mCherry (#44362). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-hM4D(Gi)-mCherry plasmid DNA. Syn-driven, Cre-dependent, hM4D(Gi) receptor with an mCherry reporter for CNO-induced neuronal inhibition. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Bryan Roth
    Article
    Krashes et al J Clin Invest. 2011 Apr;121(4):1424-8. d
    Promoter
    Syn
    Tags
    mCherry (Cre-dependent)
    Available Since
    June 21, 2017
    Availability
    Academic Institutions and Nonprofits only

  8. pAAV-hSyn-DIO-mCherry (AAV Retrograde)

    Viral Prep
    #50459-AAVrg
    Purpose
    Ready-to-use AAV Retrograde particles produced from pAAV-hSyn-DIO-mCherry (#50459). In addition to the viral particles, you will also receive purified pAAV-hSyn-DIO-mCherry plasmid DNA. hSyn-driven, Cre-dependent mCherry-expression control. These AAV were produced with a retrograde serotype, which permits retrograde access to projection neurons. These AAV preparations are suitable purity for injection into animals.
    Depositor
    Bryan Roth
    Promoter
    Syn
    Tags
    mCherry (Cre-dependent)
    Available Since
    April 1, 2019
    Availability
    Academic Institutions and Nonprofits only

  9. CRISPRi GuEST-List GFP v1

    Pooled Library
    #248189
    Purpose
    The CRISPRi Guest for Enrichment-based Screening of Targets Library (CRISPRi GuEST-List v1) enables genome-wide, single-cell pooled screens conducted with the Flex workflow from 10x Genomics.
    Depositor
    Rahul Satija
    Article
    Bradu et al bioRxiv 2026.02.12.705613
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available Since
    Feb. 17, 2026
    Availability
    Academic Institutions and Nonprofits only
Showing: 11 - 20 of 175552 results