We narrowed to 59,720 results for: sap

1. Large-scale mismatched sgRNA library for gene titration (human essential genes, CRISPRi)

   Pooled Library

   #136478

   Purpose

   Expresses gRNAs for gene titration of ~2400 human genes using CRISPRi

   Depositor

   Jonathan Weissman

   Article

   Jost et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Human ABC Transporter Knockout Sub-library with UMIs

   Pooled Library

   #221410

   Purpose

   gRNA library to test the impact of transporters on biological processes (subset: ABC transporters and controls)

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Wolf et al Cell Chem Biol. 2024 Dec 24:S2451-9456(2

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 13, 2024

   Availability

   Academic Institutions and Nonprofits only

3. BLaER1 pgRNA CRISPR library

   Pooled Library

   #183825

   Purpose

   CRISPR-Cas9 library to target lncRNAs and protein coding genes with a potential role in B-cell to macrophage transdifferentiation.

   Depositor

   Roderic Guigo

   Article

   Arnan et al BMC Genomics. 2022 May 26;23(1):402. doi

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 25, 2022

   Availability

   Academic Institutions and Nonprofits only

4. Human SLC KO Library

   Pooled Library

   #132552

   Purpose

   Expresses gRNAs for knockout of the human Solute Carrier family

   Depositor

   Giulio Superti-Furga

   Article

   Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 7, 2020

   Availability

   Academic Institutions and Nonprofits only

5. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   David Root, William Hahn

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

6. MYC-CRISPR

   Pooled Library

   #173195

   Purpose

   This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

   Depositor

   Agnieszka Dzikiewicz-Krawczyk

   Article

   Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

7. pLCKO2::TKOv3

   Pooled Library

   #125517

   Purpose

   Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

   Depositor

   Jason Moffat

   Article

   Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 1, 2019

   Availability

   Academic Institutions and Nonprofits only

8. plIG-123_HA-GD2-28z_CAR_TF_Library

   Pooled Library

   #207478

   Purpose

   HA-GD2-28z CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into th

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

9. HR700_TP53Exon5mut

   Pooled Library

   #229137

   Purpose

   Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 5 of human cells via CRISPR-HDR.

   Depositor

   Thorsten Stiewe

   Article

   Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Cre/Lox

   Available since

   Feb. 24, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

10. HR700_TP53Exon6mut

    Pooled Library

    #229138

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 6 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

11. HR700_TP53Exon7mut

    Pooled Library

    #229139

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 7 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

12. HR700_TP53Exon8mut

    Pooled Library

    #229140

    Purpose

    Donor vector library to introduce TP53 mutations into the endogenous gene locus at exon 8 of human cells via CRISPR-HDR.

    Depositor

    Thorsten Stiewe

    Article

    Funk et al Nat Genet. 2025 Jan;57(1):140-153. doi:

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Cre/Lox

    Available since

    Feb. 24, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

13. plIG-106_NY-ESO-1_TCR_SR_Library

    Pooled Library

    #207474

    Purpose

    NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

14. plIG-107_NY-ESO-1_TCR_TF_Library

    Pooled Library

    #207475

    Purpose

    NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

15. plIG-110_CD19-BBz_CAR_TF_Library

    Pooled Library

    #207477

    Purpose

    CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

16. plIG-124_HA-GD2-28z_CAR_SR_Library

    Pooled Library

    #207479

    Purpose

    HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

17. plIG-132_CD19-28z_CAR_TF_and_SR_Library

    Pooled Library

    #207481

    Purpose

    CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

    Depositor

    Alexander Marson

    Article

    Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Jan. 26, 2024

    Availability

    Academic Institutions and Nonprofits only

18. CROPseq-iT7 Human CRISPR Knockout Pooled Library (Brunello)

    Pooled Library

    #223064

    Purpose

    Optical pooled genome-scale CRISPR KO screening using Nuclear In-Situ Sequencing (NIS-Seq)

    Depositor

    Jonathan Schmid-Burgk

    Article

    Fandrey et al Nat Biotechnol. 2024 Dec 19. doi: 10.103

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    May 23, 2025

    Availability

    Academic Institutions and Nonprofits only

19. Human genome-wide lentiviral CRISPR gRNA library version 1

    Pooled Library

    #67989

    Purpose

    Human genome-wide CRISPR guide RNA library V1 (pKLV2-U6gRNA5(HumanV1)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only

20. Mouse genome-wide lentiviral CRISPR gRNA library version 2

    Pooled Library

    #67988

    Purpose

    Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

    Depositor

    Kosuke Yusa

    Article

    Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

    Species

    Homo sapiens, Mus musculus, and Synthetic

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 14, 2016

    Availability

    Academic Institutions and Nonprofits only