We narrowed to 672 results for: gcg.2

1. LCV2_PSMD1_sgRNA_1

   Plasmid

   #155091

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting PSMD1 (core essential gene)

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   PSMD1_sgRNA_1 (PSMD1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6 promoter

   Available Since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. LCV2_mCherry_PSMD1_sgRNA_1

   Plasmid

   #155107

   Purpose

   lentiviral plasmid expressing mCherry, Cas9 and a gRNA targeting PSMD1 (core essential gene)

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   PSMD1_sgRNA_1 (PSMD1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   U6 promoter

   Available Since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. pFOXF2.1.0-gDNA

   Plasmid

   #113784

   Purpose

   CRISPR plasmid for expression of Cas9 and gRNA targeting human transcription factor FOXF2

   Depositor

   Kevin White

   Insert

   FOXF2 (FOXF2 Human)
   

   Use

   CRISPR

   Expression

   Mammalian

   Available Since

   Dec. 11, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pUC19-U6-SpCas9_gRNA-OPA1-createR194G-A9-gRNA_(CJT87)

   Plasmid

   #226988

   Purpose

   pUC19 plasmid with U6 promoter and SpCas9 gRNA to create an OPA1-R194G cell line via adenine base editing (target base in position A9)

   Depositor

   Benjamin Kleinstiver

   Article

   Fry et al EMBO J. 2024 Feb;43(3):391-413. doi: 10.

   Insert

   SpCas9 gRNA A9 to create OPA1-R194G
   

   Use

   CRISPR

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   Nov. 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. PB09-TRE-beta-globin-miR-124-EF1a-GFP

   Plasmid

   #117318

   Purpose

   Overexpression of miR-124 in eurkaryotic cells, encoded in a human beta-globin intron

   Depositor

   Volker Busskamp

   Article

   Kutsche et al Cell Syst. 2018 Sep 28. pii: S2405-4712(

   Insert

   hsa-miR-124-1 (MIR124-1 Human)
   

   Use

   Transposon-mediated integration

   Tags

   GFP

   Expression

   Mammalian

   Promoter

   Tet-inducible promoter

   Available Since

   Jan. 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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6. pX458-Ef1a-Cas9-H2B-mCherry (dual gRNA: Ascl1 x2)

   Plasmid

   #171099

   Purpose

   CRISPR/Cas9 expressing plasmid containing two gRNAs targeting mouse Ascl1.

   Depositor

   Joseph Brzezinski

   Article

   Kaufman et al Development. 2021 Jun 15;148(12). pii: 2

   Insert

   hSpCas9 (Ascl1 Mouse, S. pyogenes)
   

   Use

   CRISPR

   Promoter

   Ef1a

   Available Since

   June 28, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. CRISPRi-CENPB-g2

   Plasmid

   #120210

   Purpose

   CENPB CRISPRi guide RNA 2

   Depositor

   David Bartel

   Article

   Wu et al Cell. 2017 May 18;169(5):905-917.e11. do

   Insert

   CENPB CRISPRi guide RNA
   

   Use

   CRISPR and Lentiviral

   Available Since

   March 3, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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8. pDONR223_RBM15B_WT_V5

   Plasmid

   #83010

   Purpose

   Gateway Donor vector containing RBM15B, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

   Depositor

   Matthew Meyerson, Jesse Boehm, David Root

   Article

   Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

   Insert

   RBM15B (RBM15B Human)
   

   Use

   Gateway entry vector

   Mutation

   R593K; p.1_327deleted

   Promoter

   None

   Available Since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. rTTA-gRNA-AAV

   Plasmid

   #213036

   Purpose

   This vector contains rTTA expressed under CMV promoter and gRNA expressed under U6 promoter

   Depositor

   Nadav Ahituv

   Article

   Nguyen et al Nat Biotechnol. 2025 Feb 4:10.1038/s4158

   Insert

   rTTA-T2A-mCherry
   

   Use

   AAV and CRISPR

   Promoter

   CMV

   Available Since

   Oct. 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. lenti-ERCC1 gRNA2

    Plasmid

    #211631

    Purpose

    sgRNA-2 against ERCC1

    Depositor

    Agnel Sfeir

    Article

    Brambati et al Science. 2023 Aug 11;381(6658):653-660.

    Insert

    sgRNA ERCC1
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    March 6, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pDONR223_RBM15B_WT_V5

    Plasmid

    #83010

    Purpose

    Gateway Donor vector containing RBM15B, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.

    Depositor

    Matthew Meyerson, Jesse Boehm, David Root

    Article

    Berger et al Cancer Cell. 2016 Aug 8;30(2):214-28. do

    Insert

    RBM15B (RBM15B Human)
    

    Use

    Gateway entry vector

    Mutation

    R593K; p.1_327deleted

    Promoter

    None

    Available Since

    April 24, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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12. gCH198 (crCD55-4_crB2M-1_crB2M-3_crCLTA-4_crFOLH1-1_crCD151-3_crHBG-3_crKIT-2_crKIT-3_crCD81-1)

    Plasmid

    #217345

    Purpose

    crRNA array targeting CD55, B2M, CLTA, FOLH1, CD151, HBG1/HBG2, KIT, CD81

    Depositor

    Luke Gilbert

    Article

    Hsiung et al Nat Biotechnol. 2024 May 17. doi: 10.103

    Inserts

    crCD55-4 gRNA: actggtattgcggagccacgagg (CD55 Human)
    crB2M-1 gRNA: atataagtggaggcgtcgcgctg (B2M Human)
    crB2M-3 gRNA: aggaatgcccgccagcgcgacgc (B2M Human)
    crCLTA-4 gRNA: ggctctgcaacaccgcctagacc (CLTA Human)
    crFOLH1-1 gRNA: gctccagacctggggtccagttt (FOLH1 Human)
    crCD151-3 gRNA: cgggaggccgcacccaccgcctg (CD151 Human)
    crHBG-3 gRNA: ttcttcatccctagccagccgcc (HBG1, HBG2 Human)
    crKIT-2 gRNA: tctgcgttctgctcctactgctt (KIT Human)
    crKIT-3 gRNA: agctctcgcccaagtgcagcgag (KIT Human)
    crCD81-1 gRNA: ggcgcgacccccaggaaggtctc (CD81 Human)
    

    Use

    CRISPR and Lentiviral

    Promoter

    hU6

    Available Since

    March 27, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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13. pmCherry-U6-VEGFA

    Plasmid

    #140588

    Purpose

    Expresses a gRNA and mCherry in mammalian cells

    Depositor

    Feng Zhang

    Article

    Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

    Insert

    gRNA VEGFA
    

    Use

    CRISPR

    Available Since

    May 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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14. pmCherry-U6-ALDH1A3

    Plasmid

    #140589

    Purpose

    Expresses a gRNA and mCherry in mammalian cells

    Depositor

    Feng Zhang

    Article

    Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

    Insert

    gRNA ALDH1A3
    

    Use

    CRISPR

    Available Since

    May 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. pmCherry-U6-SYNPO

    Plasmid

    #140587

    Purpose

    Expresses a gRNA and mCherry in mammalian cells

    Depositor

    Feng Zhang

    Article

    Schmid-Burgk et al Mol Cell. 2020 Mar 17. pii: S1097-2765(2

    Insert

    gRNA SYNPO
    

    Use

    CRISPR

    Available Since

    May 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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16. pJB049

    Plasmid

    #22643

    Depositor

    Lynn Hudson

    Article

    Berndt et al J Biol Chem. 1992 Jul 25. 267(21):14730-

    Insert

    human genomic PLP promoter region (POU3F2 Human)
    

    Use

    Cat reporter plasmid

    Mutation

    Site 5: CCACC to gagCg (-238 to -234bp)

    Available Since

    Nov. 24, 2009

    Availability

    Academic Institutions and Nonprofits only

17. pLY103

    Plasmid

    #130937

    Purpose

    Engineered sgRNA-LEA1 (2 BoxB aptamers) generator circuit including promoter Plux2

    Depositor

    Baojun Wang

    Article

    Liu et al Nat Commun. 2019 Aug 26;10(1):3693. doi:

    Insert

    sgRNA-LEA1
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Promoter

    Plux2

    Available Since

    Oct. 8, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLY105

    Plasmid

    #130939

    Purpose

    Engineered sgRNA-LEA3 (2 BoxB aptamers) generator circuit including promoter Plux2

    Depositor

    Baojun Wang

    Article

    Liu et al Nat Commun. 2019 Aug 26;10(1):3693. doi:

    Insert

    sgRNA-LEA3
    

    Use

    Synthetic Biology

    Expression

    Bacterial

    Promoter

    Plux2

    Available Since

    Oct. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pJB049

    Plasmid

    #22643

    Depositor

    Lynn Hudson

    Article

    Berndt et al J Biol Chem. 1992 Jul 25. 267(21):14730-

    Insert

    human genomic PLP promoter region (POU3F2 Human)
    

    Use

    Cat reporter plasmid

    Mutation

    Site 5: CCACC to gagCg (-238 to -234bp)

    Available Since

    Nov. 24, 2009

    Availability

    Academic Institutions and Nonprofits only

20. pU6-cGAS g2 Cas9-T2A-mCherry

    Plasmid

    #164253

    Purpose

    Transcription of cGAS guide RNA and Cas9 expression for CRISPR/Cas9 in mammalian cells

    Depositor

    John Maciejowski

    Article

    Mohr et al Mol Cell. 2021 Jan 12. pii: S1097-2765(2

    Insert

    sgcGAS
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    March 31, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge