167,318 results

1. Tad-CBE3.6

   Plasmid

   #235058

   Purpose

   Expresses Tad-CBE3.6 in mammalian cells.

   Depositor

   Weixin Tang

   Article

   Wu et al Nat Biotechnol. 2025 Jul 7:10.1038/s4158

   Insert

   Tad-CBE3.6-SpCas9 D10A
   

   Use

   CRISPR

   Tags

   2xUGI, SV40NLS and bpNLS

   Expression

   Mammalian

   Available Since

   July 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pET29b-Rhobin2

   Plasmid

   #239018

   Purpose

   Bacterial overexpression of de novo Rhodamine binder 2 (Rhobin2) protein

   Depositor

   William DeGrado, Bo Huang

   Article

   Chen et al bioRxiv 2025.06.24.661379

   Insert

   RhoBin2
   

   Tags

   6xHis

   Expression

   Bacterial

   Promoter

   T7

   Available Since

   June 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pMEDS

   Plasmid

   #236568

   Purpose

   Introduces a multiple expression and dual selection (MEDS) system to use alongside CRISPR for applications such as gene editing.

   Depositor

   Shannon Moonah

   Article

   Sharma et al PLoS One. 2025 May 6;20(5):e0321881. doi

   Inserts

   CD/UPRT (negative selection)
   NPT II (positive selection)
   

   Tags

   3x Myc and FLAG

   Expression

   Mammalian

   Available Since

   June 26, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLCKO-CMV-TMEM106B-P2A-Blasticidin

   Plasmid

   #237478

   Purpose

   Encodes full length human TMEM106B protein, along with blasticidin selection marker.

   Depositor

   Dirk Daelemans

   Article

   Baggen et al Cell. 2023 Aug 3;186(16):3427-3442.e22.

   Insert

   TMEM106B (TMEM106B Human)
   

   Use

   Lentiviral

   Tags

   P2A-Blasticidin

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   June 18, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV9-HCR-hAAT-SEAP-opt

   Plasmid

   #237875

   Purpose

   AAV vector / packaging plasmid: This product-specific plasmid provides a reporter encoding vector genome cassette and the AAV9 capsid gene.

   Depositor

   Florian Sonntag, Ascend Advanced Therapies

   Insert

   SEAP encoding AAV2 vector and cap9
   

   Use

   AAV

   Available Since

   June 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pAd5Rep2entire-ACGf

   Plasmid

   #237877

   Purpose

   AAV packaging plasmid: This platform plasmid provides adenoviral helper functions and the AAV2 rep gene.

   Depositor

   Florian Sonntag, Ascend Advanced Therapies

   Insert

   rep2 and E2A, E4, L4-22K/33K, VA RNA
   

   Use

   AAV

   Available Since

   June 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. CT452

   Plasmid

   #233665

   Purpose

   Red light-inducible Flp-N; Flp-N396-FHY1

   Depositor

   Wilson Wong

   Article

   Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

   Insert

   Flp-N396-FHY1
   

   Expression

   Mammalian

   Mutation

   None

   Available Since

   May 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. CT438

   Plasmid

   #233666

   Purpose

   Red light-inducible Flp-N; Flp-N27-PhyA

   Depositor

   Wilson Wong

   Article

   Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

   Insert

   Flp-N27-PhyA
   

   Expression

   Mammalian

   Mutation

   None

   Promoter

   CAG

   Available Since

   May 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. CT445

   Plasmid

   #233668

   Purpose

   Red light-inducible Flp-C; Flp-397C-PhyA

   Depositor

   Wilson Wong

   Article

   Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

   Insert

   Flp-397C-PhyA
   

   Expression

   Mammalian

   Mutation

   None

   Available Since

   May 12, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. CT447

    Plasmid

    #233663

    Purpose

    Red light-inducible Flp-C; Flp-28C-FHY1

    Depositor

    Wilson Wong

    Article

    Tous et al Sci Adv. 2025 May 9;11(19):eadt1971. doi

    Insert

    Flp-28C-FHY1
    

    Expression

    Mammalian

    Mutation

    None

    Promoter

    CAG

    Available Since

    May 12, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. TFORF1305

    Plasmid

    #143785

    Purpose

    Lentiviral vector for overexpressing transcription factor ORFs with unique 24-bp barcodes. Barcodes facilitate identification of transcription factors in pooled screens.

    Depositor

    Feng Zhang

    Article

    Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

    Insert

    ZMIZ1 (ZMIZ1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    EF1a

    Available Since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. pAAV[FLEX]-CAG-EGFP-Ctrl-sponge

    Plasmid

    #235152

    Purpose

    Expresses a EGFP-based control sponge in a Cre recombinase-dependent manner

    Depositor

    Giordano Lippi

    Article

    Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

    Insert

    EGFP/control sponge
    

    Use

    AAV

    Promoter

    CAG

    Available Since

    April 28, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCAG-SpyTag-Flag-dNS-SRRM1-V5-mCherry

    Plasmid

    #235096

    Purpose

    SRRM1 lacking Nuclear Speckle domain (dNS-SRRM1) mCherry fusion protein without MCP domain

    Depositor

    Mitchell Guttman

    Article

    Bhat et al Nature. 2024 May;629(8014):1165-1173. do

    Insert

    pCAG-SpyTag-Flag-dNS-SRRM1-V5-mCherry (SRRM1 Human)
    

    Expression

    Mammalian

    Mutation

    The SRRM1 entry clone from DNASU was modified usi…

    Promoter

    CAG

    Available Since

    April 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pAAV-rev(CMV-TagBFP2)-EFS-mCherry-206-MRE

    Plasmid

    #235156

    Purpose

    Expresses the mCherry-based sensor for miR-206. TagBFP2 is expressed as a transduction reporter

    Depositor

    Giordano Lippi

    Article

    Zolboot et al Neuron. 2025 Apr 1:S0896-6273(25)00181-3

    Insert

    mCherry with a miR-206 MRE from Tpm4
    

    Use

    AAV

    Promoter

    EFS

    Available Since

    April 23, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pcDNA3.1 N-T2A-M-IRES-E

    Plasmid

    #231903

    Purpose

    For the production of SARS-CoV-2 virus-like particles (VLPs) in the '3-plasmid' system

    Depositor

    Sriram Neelamegham

    Article

    Yang et al Nucleic Acids Res. 2025 Feb 27;53(5):gka

    Insert

    nucleocapsid protein-T2A-membrane protein-IRES-envelope protein (N, M, E SARS-CoV-2)
    

    Expression

    Mammalian

    Mutation

    R203M in N protein

    Promoter

    CMV

    Available Since

    March 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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16. FUGW-RUSH-LAMP1-V5-APEX2

    Plasmid

    #228524

    Purpose

    Lentiviral vector, expresses Strep-KDEL-IRES-SBP-(Rat)LAMP1-V5-APEX2 in mammalian cells.

    Depositor

    Ginny Farias

    Article

    Li et al Nat Commun. 2024 Dec;15: 10829. doi: 10.

    Insert

    LAMP1 (Lamp1 Rat)
    

    Use

    Lentiviral

    Tags

    Streptavidin Binding Protein (SBP), Streptavidin-…

    Expression

    Mammalian

    Promoter

    Ubc

    Available Since

    Feb. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. Str-KDEL_SBP-EGFP-ColX

    Plasmid

    #222305

    Purpose

    Synchronize the trafficking of CollagenX from the ER.

    Depositor

    Franck Perez

    Article

    Fourriere et al J Cell Biol. 2019 Jul 1;218(7):2215-2231

    Insert

    Streptavidin-KDEL and CollagenX fused to SBP-EGFP (COL10A1 Human)
    

    Expression

    Mammalian

    Mutation

    signal peptide of COL10A1 removed

    Promoter

    CMV

    Available Since

    Feb. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. Str-KDEL_SBP-EGFP-gp135

    Plasmid

    #222306

    Purpose

    Synchronize the trafficking of gp135/podocalyxin from the ER.

    Depositor

    Franck Perez

    Article

    Fourriere et al J Cell Biol. 2019 Jul 1;218(7):2215-2231

    Insert

    Streptavidin-KDEL and gp135 fused to SBP-EGFP (PODXL Rabbit)
    

    Expression

    Mammalian

    Mutation

    signal peptide removed

    Promoter

    CMV

    Available Since

    Feb. 4, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA5-FRT-TOgw-N-mCherry

    Plasmid

    #223948

    Purpose

    Gateway cloning of genes of interest with an N-terminal mCherry fusion; generation of stable cells with doxycycline inducible expression

    Depositor

    Roko Žaja, Karla Feijs

    Type

    Empty backbone

    Tags

    mCherry

    Expression

    Mammalian

    Available Since

    Oct. 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLV-shNC-mCherry

    Plasmid

    #222962

    Purpose

    Negative control for lentiviral shRNA

    Depositor

    Xinyu Zhao

    Article

    Guo et al Nat Commun. 2023 Jun 26;14(1):3801. doi:

    Insert

    Negative control
    

    Use

    Lentiviral

    Available Since

    Oct. 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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