We narrowed to 26,402 results for: vit;

1. GRK6 gRNA (BRDN0001147105)

   Plasmid

   #75705

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human GRK6

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   GRK6 (GRK6 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. CDKL3 gRNA (BRDN0001148232)

   Plasmid

   #75606

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDKL3

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDKL3 (CDKL3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. CDKL3 gRNA (BRDN0001148623)

   Plasmid

   #75607

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CDKL3

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CDKL3 (CDKL3 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. EPHA1 gRNA (BRDN0001147142)

   Plasmid

   #75590

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human EPHA1

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   EPHA1 (EPHA1 Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. CAMKV gRNA (BRDN0001162273)

   Plasmid

   #75529

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CAMKV

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CAMKV (CAMKV Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. ACVR2B gRNA (BRDN0001147208)

   Plasmid

   #75485

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ACVR2B

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ACVR2B (ACVR2B Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. ACVR2B gRNA (BRDN0001149036)

   Plasmid

   #75486

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ACVR2B

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ACVR2B (ACVR2B Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. IPMK gRNA (BRDN0001144988)

   Plasmid

   #78076

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human IPMK

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   IPMK (IPMK Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   July 5, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. CHKA gRNA (BRDN0001145792)

   Plasmid

   #76586

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CHKA

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CHKA (CHKA Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available Since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. IP6K2 gRNA (BRDN0001146075)

    Plasmid

    #77816

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human IP6K2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    IP6K2 (IP6K2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 24, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. CLK4 gRNA (BRDN0001145430)

    Plasmid

    #77797

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CLK4

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CLK4 (CLK4 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 24, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. CLK4 gRNA (BRDN0001146113)

    Plasmid

    #77798

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CLK4

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CLK4 (CLK4 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    June 24, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pcDNA3-Flag-NSF/T646A

    Plasmid

    #74937

    Purpose

    Mammalian expression of human NSF mutant T646A (mutation in the D2 domain of the protein)

    Depositor

    Elisa Greggio

    Article

    Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

    Insert

    NSF (NSF Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    T646A (mutation in the D2 domain of the protein)

    Promoter

    CMV

    Available Since

    April 26, 2016

    Availability

    Academic Institutions and Nonprofits only

14. pcDNA3-Flag-NSF/T645A

    Plasmid

    #74936

    Purpose

    Mammalian expression of human NSF mutant T645A (mutation in the D2 domain of the protein)

    Depositor

    Elisa Greggio

    Article

    Belluzzi et al Mol Neurodegener. 2016 Jan 13;11(1):1. d

    Insert

    NSF (NSF Human)
    

    Use

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    T645A (mutation in the D2 domain of the protein)

    Promoter

    CMV

    Available Since

    April 20, 2016

    Availability

    Academic Institutions and Nonprofits only

15. pcDNA3.1 E2F1 Flag(Δ 284−359)(HindIII- BamHI- EcoRI)

    Plasmid

    #70669

    Purpose

    Human mutant of E2F1 lacking amino acids 284 to 359

    Depositor

    Maria Alvarado-Kristensson

    Article

    Hoog et al FASEB J. 2011 Nov;25(11):3815-27. doi: 1

    Insert

    E2F1 lacking residues 284 to 359 (E2F1 Human)
    

    Use

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    lacks amin acids 284 to 359

    Promoter

    cmv

    Available Since

    Nov. 10, 2015

    Availability

    Academic Institutions and Nonprofits only

16. mCardinal-Keratin-17

    Plasmid

    #56164

    Purpose

    Note- This plasmid contains Keratin 18. Localization: Cytokeratin, Excitation: 604, Emission: 659

    Depositor

    Michael Davidson

    Article

    Chu et al Nat Methods. 2014 Mar 16. doi: 10.1038/n

    Insert

    Keratin (KRT18 Human)
    

    Use

    Tags

    mCardinal

    Expression

    Mammalian

    Mutation

    V282L

    Promoter

    CMV

    Available Since

    March 4, 2015

    Availability

    Industry, Academic Institutions, and Nonprofits

17. pCMV6-Entry IL36RN R48W

    Plasmid

    #58324

    Purpose

    entry vector for human IL36RN R48W mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    R48W: c.142C>T, p.Arg48Trp

    Promoter

    CMV

    Available Since

    July 30, 2014

    Availability

    Academic Institutions and Nonprofits only

18. pCMV6-Entry IL36RN P76L

    Plasmid

    #58322

    Purpose

    entry vector for human IL36RN P76L mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    P76L: c.227C>T,p.Pro76Leu​

    Promoter

    CMV

    Available Since

    July 30, 2014

    Availability

    Academic Institutions and Nonprofits only

19. pCMV6-Entry IL36RN Κ35R

    Plasmid

    #58320

    Purpose

    entry vector for human IL36RN K35R mutant

    Depositor

    Francesca Capon

    Article

    Hassi et al J Invest Dermatol. 2023 Dec;143(12):2468

    Insert

    IL36RN (IL36RN Human)
    

    Use

    Entry vector

    Tags

    myc-DDK

    Expression

    Mutation

    Κ35R: c.104A>G, p.Lys35Arg​

    Promoter

    CMV

    Available Since

    July 25, 2014

    Availability

    Academic Institutions and Nonprofits only

20. pCMV5b HA Irx5 deltaIrot

    Plasmid

    #24995

    Depositor

    Benoit Bruneau

    Article

    Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

    Insert

    Irx5 (Irx5 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Deletion of Iro box (aa 314-327), 19 aa upstream …

    Promoter

    Available Since

    Aug. 2, 2010

    Availability

    Academic Institutions and Nonprofits only

21. pCMV5b HA Irx5 deltaC

    Plasmid

    #24996

    Depositor

    Benoit Bruneau

    Article

    Costantini et al Cell. 2005 Oct 21. 123(2):347-58.

    Insert

    Irx5 (Irx5 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Deletes everything after Hox Domain (aa 112-177).…

    Promoter

    Available Since

    Aug. 2, 2010

    Availability

    Academic Institutions and Nonprofits only

22. p3xFLAG CMV14 / BRAF-G596C

    Plasmid

    #131712

    Purpose

    Mammalian Expression of Flag tagged BRAF

    Depositor

    Jacques De Grève

    Article

    Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

    Insert

    BRAF (BRAF Human)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    G596C

    Promoter

    CMV

    Available Since

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. p3xFLAG CMV14 / BRAF-G469S

    Plasmid

    #131716

    Purpose

    Mammalian Expression of Flag tagged BRAF

    Depositor

    Jacques De Grève

    Article

    Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

    Insert

    BRAF (BRAF Human)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    G469S

    Promoter

    CMV

    Available Since

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. p3xFLAG CMV14 / BRAF-V600R

    Plasmid

    #131721

    Purpose

    Mammalian Expression of Flag tagged BRAF

    Depositor

    Jacques De Grève

    Article

    Noeparast et al Oncotarget. 2016 Aug 26;8(36):60094-6010

    Insert

    BRAF (BRAF Human)
    

    Use

    Tags

    3xFLAG

    Expression

    Mammalian

    Mutation

    V600R

    Promoter

    CMV

    Available Since

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pMXs-IP-mCherry-TOSI

    Plasmid

    #172496

    Purpose

    mCherry-TOSI (TOr-Signal-Indicator) is a fluorescent reporter for mTORC1 signaling (monitoring PDCD4 degradation) which can be introduced to mammalian cells by retrovirus vector.

    Depositor

    David Scadden

    Article

    Oki et al Nat Commun. 2021 Jan 11;12(1):245. doi:

    Insert

    PDCD4 (Pdcd4 Mouse)
    

    Use

    Retroviral

    Tags

    Mcherry

    Expression

    Mammalian

    Mutation

    Promoter

    MLV LTR

    Available Since

    July 29, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. JAK1 gRNA (BRDN0001145887)

    Plasmid

    #76392

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human JAK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    JAK1 (JAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. pMXs-IP-mVenus-TOSI

    Plasmid

    #172491

    Purpose

    mVenus-TOSI (TOr-Signal-Indicator) is a fluorescent reporter for mTORC1 signaling (monitoring PDCD4 degradation) which can be introduced to mammalian cells by retrovirus vector.

    Depositor

    David Scadden

    Article

    Oki et al Nat Commun. 2021 Jan 11;12(1):245. doi:

    Insert

    Pdcd4 (Pdcd4 Mouse)
    

    Use

    Retroviral

    Tags

    mVenus

    Expression

    Mammalian

    Mutation

    Promoter

    MLV LTR

    Available Since

    Oct. 28, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pCDH-puro/Flag PD-L1 N35/3NQ

    Plasmid

    #121455

    Purpose

    expression of human PD-L1 mutant in mammalian cells

    Depositor

    Mien-Chie Hung

    Article

    Li et al Nat Commun. 2016 Aug 30;7:12632. doi: 10

    Insert

    CD274 (CD274 Human)
    

    Use

    Lentiviral

    Tags

    Flag

    Expression

    Mammalian

    Mutation

    N192Q, N200Q and N219Q

    Promoter

    CMV

    Available Since

    Feb. 2, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. CDK9 gRNA (BRDN0001162576)

    Plasmid

    #77170

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK9

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK9 (CDK9 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. CDK9 gRNA (BRDN0001146478)

    Plasmid

    #77169

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CDK9

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CDK9 (CDK9 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pLentiCMV_HyPer7RgDAAO

    Plasmid

    #217653

    Purpose

    Expresses the fusion of HyPer7,a H2O2 sensor, and Rhodotorula gracilis D amino acid oxidase (DAAO) to measure transport of D amino acids across the plasma membrane

    Depositor

    Seth Parker

    Article

    Johal et al Cell Rep. 2024 Dec 24;43(12):115069. doi

    Insert

    HyPer7 D amino acid oxidase
    

    Use

    Lentiviral

    Tags

    Nuclear export signal

    Expression

    Mammalian

    Mutation

    Fused DAAO to the C-terminus of HyPer7 using a Gl…

    Promoter

    CMV

    Available Since

    Dec. 11, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pCG_IFITM1

    Plasmid

    #179955

    Purpose

    Expression vector for human IFITM1.

    Depositor

    Frank Kirchhoff, Konstantin Sparrer

    Article

    Prelli Bozzo et al Nat Commun. 2021 Jul 28;12(1):4584.

    Insert

    IFITM1 (IFITM1 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    P13A

    Promoter

    Available Since

    Feb. 2, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pCG_IFITM2

    Plasmid

    #179956

    Purpose

    Expression vector for human IFITM2.

    Depositor

    Frank Kirchhoff, Konstantin Sparrer

    Article

    Prelli Bozzo et al Nat Commun. 2021 Jul 28;12(1):4584.

    Insert

    IFITM2 (IFITM2 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    A33V, T41M, V121I

    Promoter

    Available Since

    Feb. 2, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. ALPK1 gRNA (BRDN0001146195)

    Plasmid

    #76082

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ALPK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ALPK1 (ALPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. ALPK1 gRNA (BRDN0001146035)

    Plasmid

    #76081

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ALPK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ALPK1 (ALPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. ALPK1 gRNA (BRDN0001145294)

    Plasmid

    #76083

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ALPK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ALPK1 (ALPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. ALPK1 gRNA (BRDN0001146875)

    Plasmid

    #76084

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human ALPK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    ALPK1 (ALPK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. AAVS1-iSAM

    Plasmid

    #211495

    Purpose

    AAVS1 targeting vector containing an all-in-one DOX-inducible system for CRISPRa

    Depositor

    Lesley Forrester, Antonella Fidanza

    Article

    Petazzi et al Elife. 2024 Dec 23;13:RP94884. doi: 10.7

    Inserts

    UniSAM insert
    TET-ON
    Neo Resistance
    Insulator
    

    Use

    CRISPR and Synthetic Biology

    Tags

    T2A-mCherry Tag

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a, NA, Splicing acceptor, and TREGV promoter

    Available Since

    Dec. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pLenti_EF1a_Flag_TP53_WT

    Plasmid

    #183112

    Purpose

    Expresses flag-tagged p53 in mammalian cells

    Depositor

    William Kaelin

    Article

    Stransky et al Proc Natl Acad Sci U S A. 2022 Apr 5;119

    Insert

    TP53 (TP53 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    See Depositor Comments Below

    Promoter

    EF1a

    Available Since

    Aug. 24, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. EIF2AK2 gRNA (BRDN0001148577)

    Plasmid

    #75638

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human EIF2AK2

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    EIF2AK2 (EIF2AK2 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge