We narrowed to 59,035 results for: {{{s}}}

1. Mouse sphingolipid metabolism knockout library

   Pooled Library

   #206249

   Purpose

   The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

   Depositor

   Kivanc Birsoy

   Article

   Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 29, 2024

   Availability

   Academic Institutions and Nonprofits only

2. pC004 - PFS library in Beta-lactamase gene Target Plasmid

   Pooled Library

   #79153

   Purpose

   PFS library inserted at the 5' of the Beta-lactamase gene for screening PFS preference

   Depositor

   Feng Zhang

   Article

   Abudayyeh et al Science. 2016 Jun 2. pii: aaf5573.

   Available since

   Oct. 26, 2017

   Availability

   Academic Institutions and Nonprofits only

3. pAAV-TPH2-Cre

   Plasmid

   #189616

   Purpose

   Expresses Cre recombinase under the control of the tryptophan hydroxylase promoter

   Depositor

   David Clapham

   Article

   Sheu et al Cell. 2022 Sep 1;185(18):3390-3407.e18.

   Insert

   Cre Recombinase
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Tph2

   Available since

   March 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. TALED_Right-Cox3.1-1397C-AD.

   Plasmid

   #212953

   Purpose

   ExpressesTALED_Right-Cox3.1-1397C-AD in mammalian cells

   Depositor

   Jin-Soo Kim

   Article

   Cho et al Cell. 2024 Jan 4;187(1):95-109.e26. doi:

   Insert

   TALED_Right-Cox3.1-1397C-AD
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. TALED_Left-Cox3.1-1397N.

   Plasmid

   #212950

   Purpose

   Expresses TALED_Left-Cox3.1-1397N. in mammalian cells

   Depositor

   Jin-Soo Kim

   Article

   Cho et al Cell. 2024 Jan 4;187(1):95-109.e26. doi:

   Insert

   TALED_Left-Cox3.1-1397N
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. TALED_Left-mouse-ATP6-1397N.

   Plasmid

   #212951

   Purpose

   Expresses TALED_Left-mouse-ATP6-1397N in mammalian cells

   Depositor

   Jin-Soo Kim

   Article

   Cho et al Cell. 2024 Jan 4;187(1):95-109.e26. doi:

   Insert

   TALED_Left-mouse-ATP6-1397N (ATP6 Synthetic)
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   April 2, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pAAV-Syn1-GRAB-HTR6-cilia

   Plasmid

   #189615

   Purpose

   Expresses cilia-targeted serotonin sensor based on HTR6 receptor and cpEGFP, driven by SYN promoter

   Depositor

   David Clapham

   Article

   Sheu et al Cell. 2022 Sep 1;185(18):3390-3407.e18.

   Insert

   HTR6_GRAB
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   Syn1

   Available since

   March 15, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. pMRX-IRES-puro-3xFLAG-NBR1

   Plasmid

   #204546

   Purpose

   Expresses 3xFLAG-tagged NBR1 in mammalian cells

   Depositor

   Masaaki Komatsu

   Article

   Kurusu et al Dev Cell. 2023 May 9:S1534-5807(23)00191

   Insert

   NBR1 (NBR1 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   None

   Promoter

   Available since

   Aug. 25, 2023

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. TALED_Left-ND6-1397N

   Plasmid

   #212952

   Purpose

   Expresses TALED_Left-ND6-1397N in mammalian cells

   Depositor

   Jin-Soo Kim

   Article

   Cho et al Cell. 2024 Jan 4;187(1):95-109.e26. doi:

   Insert

   TALED_Left-ND6-1397N
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   March 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. TALED_Right-ND6-1397C-AD

    Plasmid

    #212956

    Purpose

    Expresses TALED_Right-ND6-1397C-AD in mammalian cells

    Depositor

    Jin-Soo Kim

    Article

    Cho et al Cell. 2024 Jan 4;187(1):95-109.e26. doi:

    Insert

    TALED_Right-ND6-1397C-AD
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    March 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pMRX-IRES-puro-3xFLAG-NBR1 deltaUBA

    Plasmid

    #204547

    Purpose

    Expresses 3xFLAG-tagged NBR1 deltaUBA in mammalian cells

    Depositor

    Masaaki Komatsu

    Article

    Kurusu et al Dev Cell. 2023 May 9:S1534-5807(23)00191

    Insert

    NBR1 (NBR1 Human)
    

    Use

    Retroviral

    Tags

    Expression

    Mammalian

    Mutation

    deltaUBA

    Promoter

    Available since

    Aug. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. AdEasier-1 cells (strain)

    Bacterial Strain

    #16399

    Depositor

    Bert Vogelstein

    Article

    He et al Proc Natl Acad Sci U S A. 1998 Mar 3. 95

    Bacterial Resistance

    Ampicillin and streptomycin

    Species

    Escherichia coli

    Available since

    June 11, 2008

    Availability

    Academic Institutions and Nonprofits only

13. YjdC-R82A_pET-14b

    Plasmid

    #233276

    Purpose

    Overexpress his-tag YjdC protein with a site directed mutagenesis, arginine at position 82 was substituted with alanine (R82A)

    Depositor

    Mohan Babu, Andrew Emili

    Article

    Peng et al Cell. 2025 Jan 22:S0092-8674(25)00032-7.

    Insert

    YjdC (yjdC )
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Arginine was replaced with Alanine at position 82…

    Promoter

    T7 promoter

    Available since

    March 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. YjdC-R64A_pET-14b

    Plasmid

    #233263

    Purpose

    Overexpress his-tag YjdC protein with a site directed mutagenesis, arginine at position 64 was substituted with alanine (R64A)

    Depositor

    Mohan Babu, Andrew Emili

    Article

    Peng et al Cell. 2025 Jan 22:S0092-8674(25)00032-7.

    Insert

    YjdC (yjdC )
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    Arginine was replaced with Alanine at position 64…

    Promoter

    T7 promoter

    Available since

    March 17, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pCMV-HA-MyD88

    Plasmid

    #12287

    Depositor

    Bruce Beutler

    Article

    Jiang et al Proc Natl Acad Sci U S A. 2006 Jul 18. 1

    Insert

    MyD88 (MYD88 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Jan. 25, 2007

    Availability

    Academic Institutions and Nonprofits only

    

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16. pGAL4-DBD-MCS

    Plasmid

    #145245

    Purpose

    Backbone vector expressing GAL4 DNA-binding domain followed by MCS

    Depositor

    Denes Hnisz

    Article

    Basu et al Cell. 2020 May 28;181(5):1062-1079.e30.

    Type

    Empty backbone

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 21, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. pHR-mCherry-CRY2-NLS

    Plasmid

    #145259

    Purpose

    Mammalian Expression of Nuclear Control OptoConstruct with SV40 NLS

    Depositor

    Denes Hnisz

    Article

    Basu et al Cell. 2020 May 28;181(5):1062-1079.e30.

    Type

    Empty backbone

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Sept. 22, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pcDNA-HA-Nedd4/2795

    Plasmid

    #11426

    Depositor

    Allan Weissman

    Article

    Magnifico et al J Biol Chem. 2003 Oct 31. 278(44):43169-

    Insert

    Nedd4-1 (Nedd4 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    D661N compared to GenBank reference sequence U966…

    Promoter

    CMV

    Available since

    April 20, 2006

    Availability

    Academic Institutions and Nonprofits only

    

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19. pcDNA-HA-Nedd4(C744E)/2797

    Plasmid

    #11206

    Depositor

    Allan Weissman

    Article

    Magnifico et al J Biol Chem. 2003 Oct 31. 278(44):43169-

    Insert

    Nedd4-1 (Nedd4 Mouse)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    cysteine 744 mutated to glutamic acid

    Promoter

    Available since

    March 8, 2006

    Availability

    Academic Institutions and Nonprofits only

20. CCR5-donor-MCS

    Plasmid

    #192269

    Purpose

    Donor template for CRISPR Genome Editing

    Depositor

    Shantanu Chowdhury

    Article

    Sharma et al Cell Rep. 2021 May 18;35(7):109154. doi:

    Insert

    MCS within donor template
    

    Use

    CRISPR

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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