We narrowed to 10,563 results for: ESP

1. pCMV-SpCas9-VRQR(+T1138K)-P2A-EGFP (LRF243)

   Plasmid

   #242674

   Purpose

   CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(T1138K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

   Depositor

   Benjamin Kleinstiver

   Article

   Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

   Insert

   pCMV-SpCas9-VRQR(T1138K)-BPNLS(SV40)-3xFLAG-P2A-EGFP
   

   Use

   CRISPR

   Tags

   BPNLS

   Expression

   Mammalian

   Mutation

   VRQR + T1138K mutations in SpCas9(D1135V/T1138K/G…

   Promoter

   CMV and T7

   Available Since

   Oct. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCMV-SpCas9-VRQR(+D1332K)-P2A-EGFP (KAC966)

   Plasmid

   #242680

   Purpose

   CMV promoter expression plasmid for human codon optimized SpCas9-VRQR(D1332K)-BPNLS(SV40)-3xFLAG-P2A-EGFP

   Depositor

   Benjamin Kleinstiver

   Article

   Alves et al Nat Biomed Eng. 2025 Sep 11:10.1038/s415

   Insert

   pCMV-SpCas9-VRQR(D1332K)-BPNLS(SV40)-3xFLAG-P2A-EGFP
   

   Use

   CRISPR

   Tags

   BPNLS

   Expression

   Mammalian

   Mutation

   VRQR + D1332K mutations in SpCas9(D1135V/G1218R/D…

   Promoter

   CMV and T7

   Available Since

   Oct. 9, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. CoV2-Spike-D614G-S13I

   Plasmid

   #177965

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, S13I)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, S13I) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, S13I

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. CoV2-Spike-D614G-T20N

   Plasmid

   #177966

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, T20N)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, T20N) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, T20N

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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5. CoV2-Spike-D614G-P26S

   Plasmid

   #177967

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, P26S)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, P26S) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, P26S

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. CoV2-Spike-D614G-W152C

   Plasmid

   #177968

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, W152C)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, W152C) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, W152C

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. CoV2-Spike-D614G-P681H

   Plasmid

   #177973

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, P681H)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, P681H) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, P681H

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. CoV2-Spike-D614G-D1118H

   Plasmid

   #177974

   Purpose

   Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (D614G, D1118H)

   Depositor

   Melanie Ott

   Article

   Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

   Insert

   SARS-CoV-2 Spike protein (D614G, D1118H) (S )
   

   Expression

   Mammalian

   Mutation

   D614G, D1118H

   Available Since

   Nov. 17, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. pcDNA3.1_ spike_del19

   Plasmid

   #155297

   Purpose

   Expression of spike with C-term deletion of 19 aa, used to generate high efficiency SARS-CoV-2-pseudotyped lentiviral particles

   Depositor

   Raffaele De Francesco

   Article

   Conforti et al Mol Ther. 2021 Sep 20. pii: S1525-0016(2

   Insert

   SARS-Cov2 spike_deleted (S SARS-Cov2)
   

   Use

   Generation of sars-cov-2-pseudotyped lentiviral p…

   Mutation

   Deletion in C-term 19 aa of spike

   Promoter

   CMV

   Available Since

   Aug. 5, 2020

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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10. pKT-IDH1(R132H)-IRES-Katushka

    Plasmid

    #124257

    Purpose

    Expresses IDH1 with a R132H mutation and katushka fluorescent reporter. Construct has inverted repeats to be used in Sleeping Beauty transposon system.

    Depositor

    Maria Castro

    Article

    Nunez et al Sci Transl Med. 2019 Feb 13;11(479). pii

    Insert

    Isocitrate dehydrogenase 1 (R132H) (IDH1 Human)
    

    Expression

    Mammalian

    Mutation

    Arginine 132 is mutated to Histidine. This mutati…

    Available Since

    Sept. 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. CoV2-Spike-D614G-Alpha

    Plasmid

    #177961

    Purpose

    Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Alpha: del69,70, del144, D614G, N501Y, A570D, P681H, T716I, S982A, D1118H)

    Depositor

    Melanie Ott

    Article

    Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

    Insert

    SARS-CoV-2 Spike protein (Alpha: del69, 70, del144, D614G, N501Y, A570D, P681H, T716I, S982A, D1118H) (S )
    

    Expression

    Mammalian

    Mutation

    del69, 70, del144, D614G, N501Y, A570D, P681H, T7…

    Available Since

    Nov. 17, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. pUC18_BCR_GUSB_ABL1_e14a3

    Plasmid

    #190885

    Purpose

    molecular monitoring of atypical BCR::ABL1 fusion transcripts

    Depositor

    Nicholas Cross

    Article

    Schafer et al J Cancer Res Clin Oncol. 2021 Oct;147(10

    Inserts

    e14a3 BCR::ABL1 fusion transcript
    ABL1 cDNA (ABL1 Human)
    GUSB cDNA (GUSB Human)
    BCR (BCR Human)
    

    Use

    Cloned cdna transcripts for use in rt-qpcr bcr::a…

    Available Since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. PB-GG-OMKSL-PGK-Puro

    Plasmid

    #102894

    Purpose

    PiggyBac transposon system construct with 10 concatenated U6 promoter driven transcriptional cassettes targeting OCT4, MYC, KLF4, SOX2 and LIN28A promoters. Contains PGK-puro selection cassette.

    Depositor

    Timo Otonkoski

    Article

    Weltner et al Nat Commun. 2018 Jul 6;9(1):2643. doi: 1

    Insert

    OMKSL-gRNAs-PGK-Puro (POU5F1, MYC, KLF4, SOX2, LIN28A Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 10, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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14. PB-EEA-5g-OSK2M2L1-PGK-Puro

    Plasmid

    #102909

    Purpose

    PiggyBac transposon system construct for expression of 10 gRNAs targeting OCT4, MYC, KLF4, SOX2 and LIN28A promoters and 5 gRNAs targeting EEA-motif. Includes PGK-puro selection cassette.

    Depositor

    Timo Otonkoski

    Article

    Weltner et al Nat Commun. 2018 Jul 6;9(1):2643. doi: 1

    Insert

    EEA-5g-OSK2M2L1-gRNAs-PGK-Puro (POU5F1, SOX2, KLF4, MYC, LIN28A Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 10, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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15. CoV2-Spike-D614G-Gamma

    Plasmid

    #177963

    Purpose

    Transient mammalian expression of codon optimized SARS-CoV-2 Spike protein (Gamma: L13F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F)

    Depositor

    Melanie Ott

    Article

    Deng et al Cell. 2021 Jun 24;184(13):3426-3437.e8.

    Insert

    SARS-CoV-2 Spike protein (Gamma: L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N501Y, D614G, H655Y, T1027I, V1176F) (S )
    

    Expression

    Mammalian

    Mutation

    L18F, T20N, P26S, D138Y, R190S, K417T, E484K, N50…

    Available Since

    Nov. 18, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. GG-EBNA-OMKSL-PP

    Plasmid

    #102899

    Purpose

    EBNA episome plasmid for U6 promoter-driven expression of 10 gRNAs targeting OCT4, MYC, KLF4, SOX2 and LIN28A promoters. Includes PGK-puro selection cassette.

    Depositor

    Timo Otonkoski

    Article

    Weltner et al Nat Commun. 2018 Jul 6;9(1):2643. doi: 1

    Insert

    OMKSL-gRNAS-PGK-puro (POU5F1, MYC, KLF4, SOX2, LIN28A Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 10, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAAV.CAGFLEX.(cyto).cpSFGFP.HaloTag (AAV5)

    Viral Prep

    #209658-AAV5

    Purpose

    Ready-to-use AAV5 particles produced from pAAV.CAGFLEX.(cyto).cpSFGFP.HaloTag (#209658). In addition to the viral particles, you will also receive purified pAAV.CAGFLEX.(cyto).cpSFGFP.HaloTag plasmid DNA. CAG-driven, Cre-dependent expression of cpSFGFP.HaloTag (non-responsive control). These AAV preparations are suitable purity for injection into animals.

    Depositor

    Tim Brown, HHMI-JRC Tool Translation Team

    Article

    Marvin et al Proc Natl Acad Sci U S A. 2024 May 21;12

    Promoter

    CAG

    Tags

    SFGFP

    Available Since

    Oct. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

18. AiP12039 - pAAV-3xSP10ins-AiE0354h-minRho-SYFP2-WPRE3-BGHpA (Alias: CN2039)

    Plasmid

    #208401

    Purpose

    AiE0354h is an enhancer sequence designed to drive AAV-mediated transgene expression in Vip+ cortical interneurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Lee et al Science. 2023 Oct 13;382(6667):eadf6484.

    Insert

    SYFP2
    

    Use

    AAV and Synthetic Biology

    Expression

    Mammalian

    Promoter

    eHGT_354h (enhancer)

    Available Since

    Jan. 10, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. AiP14908 - pAAV-AiE0354h-minBG-mScarlet-WPRE3-BGHpA (Alias: CN4908)

    Plasmid

    #224052

    Purpose

    AiE0354h is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical Vip+ neurons

    Depositor

    Allen Institute for Brain Science, Jonathan Ting

    Article

    Ben-Simon et al bioRxiv [Preprint]. 2024 Sep 26:2024.06.

    Insert

    mScarlet
    

    Use

    AAV

    Mutation

    NA

    Promoter

    minBG

    Available Since

    Oct. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. AiP1911 - pAAV-AiE2114m-minBG-iCre-WPRE-BGHpA

    Plasmid

    #220719

    Purpose

    AiE2114m is an enhancer sequence, designed to induce cre-dependent recombination in specific populations of brain cells

    Depositor

    Allen Institute for Brain Science, Bosiljka Tasic

    Article

    Ben-Simon et al bioRxiv [Preprint]. 2024 Sep 26:2024.06.

    Insert

    iCre
    

    Use

    AAV

    Promoter

    minBG

    Available Since

    Feb. 20, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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