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Plasmid#32479PurposeCre-dependent expression of PSAM-GlyR (L141F) neuronal inhibitor, with IRES-EGFP markerDepositorInsertPSAML141F-GlyR-IRES-GFP
UseAAV and Cre/Lox; Adeno-associated virus, flex swi…TagsIRES-EGFPExpressionMutationPromoterSynapsinAvailable sinceJan. 13, 2012AvailabilityAcademic Institutions and Nonprofits only -
pCLXEBR-pTF-hM3Dq
Plasmid#114283PurposeTET-inducible expression of the hM3Dq proteinDepositorInserthM3Dq
UseLentiviralTagsExpressionMutationPromoterAvailable sinceNov. 16, 2018AvailabilityAcademic Institutions and Nonprofits only -
pAAV-CamKII-DIO-hM4D(Gi)-mCherry
Plasmid#190240PurposeExpresses iDREADD fused to mCherry flanked by DIODepositorInserthM4D(Gi)-mCherry
UseAAVTagsmCherryExpressionMutationPromotermouse CamKII alphaAvailable sinceOct. 27, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-OTp-hM3Dq-Myc
Plasmid#184753PurposeTo drive hM3D fused with Myc tag under the control of mouse oxytocin promoterDepositorInserthM3D (Gq)
UseAAVTags3xMycExpressionMutationPromotermouse Oxytocin promoterAvailable sinceMay 27, 2022AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shScg2-CWB
Plasmid#223659PurposeExpresses hM3D(Gq) and a shRNA targetting Scg2 in a Cre-dependent mannerDepositorInserthM3D(Gq)-mCherry and shScg2
UseAAV and RNAiTagsmCherryExpressionMammalianMutationPromoterhSynAvailable sinceApril 30, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shLacZ-CWB
Plasmid#223660PurposeExpresses hM3D(Gq) and a control shRNA (targetting LacZ) in a Cre-dependent mannerDepositorInserthM3D(Gq)-mCherry and shLacZ
UseAAV and RNAiTagsmCherryExpressionMammalianMutationPromoterhSynAvailable sinceApril 30, 2025AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-DIO-hM3D(Gq)-mCherry-shVgf-CWB
Plasmid#223658PurposeExpresses hM3D(Gq) and a shRNA targetting VGF in a Cre-dependent mannerDepositorInserthM3D(Gq)-mCherry and shVGF
UseAAV and RNAiTagsmCherryExpressionMammalianMutationPromoterhSynAvailable sinceApril 30, 2025AvailabilityAcademic Institutions and Nonprofits only -
AAV-mOXT-hM3Dq-mCherry-WPRE
Plasmid#70717PurposeExpresses DREADDs Gq receptor under oxytocin promoter controlDepositorInserthM3Dq-mCherry
UseAAVTagsmCherryExpressionMutationPromotermouse oxytocinAvailable sinceJan. 22, 2016AvailabilityAcademic Institutions and Nonprofits only -
pAAV EFIa DIO LMO11 (GeNL_SS-ChRmine)
Plasmid#219426PurposeCre-dependent expression of luciferase opsin fusion protein for bioluminescent optogeneticsDepositorInsertmNeonGreen, ISN-IE, ChRmine
UseAAVTagsGaussia luciferase signal sequenceExpressionMutationPromoterEF-1alphaAvailable sinceJune 3, 2024AvailabilityAcademic Institutions and Nonprofits only -
pAAV hSyn FLEx-FRT hM3Dq-mCherry
Plasmid#161575PurposeExpression of hM3Dq-mCherry in a Flp-dependent fashionDepositorInserthM3Dq-mCherry
UseAAVTagsExpressionMutationNAPromoterhSynAvailable sinceNov. 20, 2020AvailabilityAcademic Institutions and Nonprofits only -
rAAV-syn::FLEX-rev::PSAML141F,Y115F:5HT3HC-IRES-GFP
Plasmid#32477PurposeCre-dependent expression of PSAM-5HT3 HC (L141F,Y115F) neuronal activator, with IRES-EGFP markerDepositorInsertPSAML141F,Y115F-5HT3HC
UseAAV and Cre/Lox; Adeno-associated virus, flex swi…TagsIRES-EGFPExpressionMutationPromoterSynapsinAvailable sinceJan. 12, 2012AvailabilityAcademic Institutions and Nonprofits only -
pAAV hSyn FLEx-FRT hM4Di-mCherry
Plasmid#161576PurposeExpression of hM4Di-mCherry in a Flp-dependent fashionDepositorInserthM4Di-mCherry
UseAAVTagsExpressionMutationNAPromoterhSynAvailable sinceNov. 20, 2020AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-CAG-sbGLuc-hGtARC2-EYFP
Plasmid#114111Purposefusion protein of Gaussia luciferase variant slow burn, Guillardia theta anion channelrhodopsin-2, and enhanced yellow fluorescent protein for bioluminescent optogeneticsDepositorInsertGaussia luciferase, slow burn; Guillardia theta anion channelrhodopsin-2, human codon optimized
UseTagsExpressionMammalianMutationPromoterCAGAvailable sinceAug. 9, 2019AvailabilityAcademic Institutions and Nonprofits only -
AAVS1-Pur-CAG-hM3Dq-mCherry
Plasmid#80948Purposehuman AAVS1 site targeting donor plasmid for knock-in hM3Dq-mCherry expression cassette driven by CAG promoterDepositorInserthM3Dq-mCherry
UseTagsmcherry fusionExpressionMammalianMutationPromoterCAG promoterAvailable sinceApril 6, 2017AvailabilityAcademic Institutions and Nonprofits only -
rAAV-CAG::FLEX-rev:: hM4D-2a-GFP
Plasmid#52536PurposeCo-expresses hM4D and a green fluorescent label from a Cre-dependent virusDepositorUseAAV and Cre/LoxTagsExpressionMutationPromoterCAGAvailable sinceJune 10, 2014AvailabilityAcademic Institutions and Nonprofits only -
pAAV-hSyn-sbGLuc-ChR2(CS/DA)-EYFP
Plasmid#114106Purposefusion protein of Gaussia luciferase variant slow burn, Channelrhodopsin-2 variant C128S/D156A (stabilized step function opsin), and enhanced yellow fluorescent protein for bioluminescent optogeneticsDepositorInsertGaussia luciferase, slow burn; Channelrhodopsin 2(CS/DA), stable step function opsin; EYFP
UseAAVTagsExpressionMammalianMutationPromoterhSynAvailable sinceAug. 6, 2019AvailabilityAcademic Institutions and Nonprofits only -
AAVS1-Pur-CAG-hM4Di-mCherry
Plasmid#80947Purposehuman AAVS1 site targeting donor plasmid for knock-in hM4Di-mCherry expression cassette driven by CAG promoterDepositorInserthM4Di-mCherry
UseTagsmcherry fusionExpressionMammalianMutationPromoterCAG promoterAvailable sinceNov. 10, 2016AvailabilityAcademic Institutions and Nonprofits only -
rAAV-syn::FLEX-rev::PSAMQ79G,Q139G:5HT3HC-IRES-GFP
Plasmid#32475PurposeCre-dependent expression of PSAM-5HT3 HC (Q79G,Q139G) neuronal activator, with IRES-EGFP markerDepositorInsertPSAMQ79G,Q139G-5HT3HC
UseAAV and Cre/Lox; Adeno-associated virus, flex swi…TagsIRES-EGFPExpressionMutationPromoterSynapsinAvailable sinceDec. 12, 2011AvailabilityAcademic Institutions and Nonprofits only -
pAAV hSyn FLEx-loxp hM4Di-mCherry
Plasmid#161581PurposeExpression of hM4Di-mCherry in a cre-dependent fashionDepositorInserthM4Di-mCherry
UseAAVTagsExpressionMutationNAPromoterhSynAvailable sinceNov. 20, 2020AvailabilityAcademic Institutions and Nonprofits only -
pcDNA3.1-CAG-LMO1 (GLuc-ChR2-EYFP)
Plasmid#72888Purposefusion protein of Gaussia luciferase, Channelrhodopsin-2, and enhanced yellow fluorescent protein for bioluminescent optogeneticsDepositorInsertGaussia luciferase, Channelrhodopsin-2, EYFP
UseTagsExpressionBacterial and MammalianMutationPromoterCAGAvailable sinceAug. 27, 2019AvailabilityAcademic Institutions and Nonprofits only