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shTCF7L2 # 2

Plasmid

#42558

Depositor

William Hahn

Article

Rosenbluh et al Cell. 2012 Dec 21;151(7):1457-73. doi: 1

Insert

shTCF7L2 (TCF7L2 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Feb. 14, 2013

Availability

Academic Institutions and Nonprofits only
shTBX5 # 1

Plasmid

#42549

Depositor

William Hahn

Article

Rosenbluh et al Cell. 2012 Dec 21;151(7):1457-73. doi: 1

Insert

shTBX5 (TBX5 Human)

Use

Lentiviral and RNAi

Expression

Mammalian

Available Since

Feb. 8, 2013

Availability

Academic Institutions and Nonprofits only
pRSITEP-puro-shWRN2

Plasmid

#125785

Purpose

DOX-inducible expression of a short-hairpin RNA targeting human WRN

Depositor

Francisca Vazquez

Article

Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

Insert

shWRN2 (WRN Human)

Use

RNAi

Available Since

Aug. 21, 2019

Availability

Academic Institutions and Nonprofits only

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lentiCRISPRv2_AMBRA1#2

Plasmid

#174153

Purpose

Lentiviral vector expressing Cas9 and a sgRNA against the human AMBRA1 gene

Depositor

Julien Sage

Article

Chaikovsky et al Nature. 2021 Apr;592(7856):794-798. doi:

Insert

AMBRA (AMBRA1 Human)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

Sept. 10, 2021

Availability

Academic Institutions and Nonprofits only

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pRSETC-PITPbeta (splice variant 1) K61A

Plasmid

#58271

Purpose

bacterial expression of PITP beta K61A mutant (phosphatidylinositol transfer protein beta)

Depositor

Shamshad Cockcroft

Article

Shadan et al Traffic. 2008 Sep;9(10):1743-56. doi: 10

Insert

PITP beta (PITPNB Human)

Tags

HIS

Expression

Bacterial

Mutation

K61A (abolishes PI binding)

Promoter

T7

Available Since

July 15, 2014

Availability

Academic Institutions and Nonprofits only
pLenti-PGK-EV-Hygro

Plasmid

#253791

Purpose

pLenti lentiviral expression vector encoding empty vector under a human PGK promoter.

Depositor

Samuel McBrayer

Article

Savani et al Nat Metab. 2026 Apr 29. doi: 10.1038/s42

Type

Empty backbone

Use

Lentiviral

Expression

Mammalian

Available Since

May 1, 2026

Availability

Academic Institutions and Nonprofits only

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pAAV-EF1α-GRAB_PGE2mut

Plasmid

#251356

Purpose

Express the PGE2-insensitive control sensor GRAB_PGE2mut in mammalian cells

Depositor

Yulong Li

Article

Wang et al bioRxiv [Preprint]. 2025 Jun 3:2025.06.0

Insert

PGE2-insensitive sensor GRAB_PGE2mut (control sensor)

Use

AAV

Expression

Mammalian

Promoter

EF1α

Available Since

May 14, 2026

Availability

Academic Institutions and Nonprofits only

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pminiTol2-5xUAS-sfGFP-zP2A-zB19G-zT2A-zTVA (UGBT)

Plasmid

#240274

Purpose

Helper plasmid for zebrafish rabies virus based-circuit tracing

Depositor

Xufei Du

Article

Chen et al eLife 2024 [Reviewed Preprint] 13:RP1008

Inserts

B19G (codon-optimized for Danio rerio)
sfGFP (codon-optimized for Danio rerio)
TVA (codon-optimized for Danio rerio)

Use

Zebrafish expression

Available Since

April 15, 2026

Availability

Academic Institutions and Nonprofits only

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Delta6_ftnA-ftnA

Plasmid

#253339

Purpose

Delta6 tagged ferritin

Depositor

Qiangjun Zhou

Article

Luo et al bioRxiv [Preprint]. 2026 Jan 20:2026.01.

Insert

Delta6-ftnA-ftnA (ftnA E. coli)

Expression

Bacterial

Available Since

March 25, 2026

Availability

Academic Institutions and Nonprofits only

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V12_ftnA-ftnA

Plasmid

#253338

Purpose

V12 tagged ferritin

Depositor

Qiangjun Zhou

Article

Luo et al bioRxiv [Preprint]. 2026 Jan 20:2026.01.

Insert

V12-ftnA-ftnA (ftnA E. coli)

Expression

Bacterial

Promoter

T7

Available Since

March 19, 2026

Availability

Academic Institutions and Nonprofits only

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pEF-1a_EGFP_IRES_BSD_WPRE

Plasmid

#251221

Purpose

Lentiviral transfer plasmid for the generation of EF1a driven EGFP expressing cells

Depositor

Niels Geijsen

Article

Bot et al Commun Biol. 2026 Jan 19;9(1):233. doi:

Insert

EGFP

Use

Lentiviral

Expression

Mammalian

Promoter

EF-1a

Available Since

March 19, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-XRN2_sgRNA_2

Plasmid

#242896

Purpose

PiggyBac cargo vector with XRN2 sgRNA 2 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

XRN2 (Xrn2 Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-HNRNPU_sgRNA_5

Plasmid

#242900

Purpose

PiggyBac cargo vector with HNRNPU sgRNA 5 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

HNRNPU (Hnrnpu Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-HNRNPU_sgRNA_1

Plasmid

#242901

Purpose

PiggyBac cargo vector with HNRNPU sgRNA 1 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

HNRNPU (Hnrnpu Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-HNRNPU_sgRNA_3

Plasmid

#242902

Purpose

PiggyBac cargo vector with HNRNPU sgRNA 3 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

HNRNPU (Hnrnpu Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-HNRNPL_sgRNA_3

Plasmid

#242892

Purpose

PiggyBac cargo vector with HNRNPL sgRNA 3 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

HNRNPL (Hnrnpl Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-YTHDC1_sgRNA_4

Plasmid

#242893

Purpose

PiggyBac cargo vector with YTHDC1 sgRNA 4 for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

YTHDC1 (Ythdc1 Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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PB_rtTA_BsmB-YTHDC1_sgRNA_2a

Plasmid

#242894

Purpose

PiggyBac cargo vector with YTHDC1 sgRNA 2a for dox-inducible knockdown

Depositor

Mauro Calabrese

Article

Murvin et al bioRxiv 2025.07.16.665154

Insert

YTHDC1 (Ythdc1 Mouse)

Use

CRISPR

Promoter

U6

Available Since

Feb. 5, 2026

Availability

Academic Institutions and Nonprofits only

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pmScarlet LRRK1 D1409A

Plasmid

#241257

Purpose

For exogenous expression of LRRK1 D1409A as an N-terminal fusion to mScarlet in mammalian cells

Depositor

Pietro De Camilli

Article

Hanna et al EMBO J (2025) 44: 6168 - 6195

Insert

LRRK1 D1409A (LRRK1 Human)

Tags

mScarlet

Expression

Mammalian

Mutation

D1409A

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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pACEBac_eIF2_gamma

Plasmid

#248693

Purpose

Express the human eIF2 gamma subunit in insect cells or clone it in other vectors

Depositor

Venki Ramakrishnan

Article

Diaz-Lopez et al Protein Sci. 2026 Jan;35(1):e70388. doi:

Insert

eIF2 gamma (EIF2S3 Human)

Tags

3C STREP 2

Expression

Insect

Mutation

WT

Promoter

Polyhedrin

Available Since

Jan. 7, 2026

Availability

Academic Institutions and Nonprofits only

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