We narrowed to 8,392 results for: crispr grnas

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Lenti-sgRasa1#1/Cre

Plasmid

#173649

Purpose

Expresses a Rasa1-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Rasa1 (Rasa1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 17, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgTet2#1/Cre

Plasmid

#173655

Purpose

Expresses a Tet2-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Tet2 (Tet2 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 17, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgStag2#1/Cre

Plasmid

#173659

Purpose

Expresses a Stag2-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Stag2 (Stag2 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 17, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgStag2#2/Cre

Plasmid

#173660

Purpose

Expresses a Stag2-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Stag2 (Stag2 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 17, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgDot1l#2/Cre

Plasmid

#173590

Purpose

Expresses a Dot1l-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Dot1l (Dot1l Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgPole#1/Cre

Plasmid

#173609

Purpose

Expresses a Pole-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Pole (Pole Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgErcc4#2/Cre

Plasmid

#173594

Purpose

Expresses a Ercc4-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Ercc4 (Ercc4 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgAtm#2/Cre

Plasmid

#173580

Purpose

Expresses a Atm-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Atm (Atm Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 12, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgBap1#1/Cre

Plasmid

#173581

Purpose

Expresses a Bap1-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Bap1 (Bap1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 9, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgAtf7ip#2/Cre

Plasmid

#173578

Purpose

Expresses a Atf7ip-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Atf7ip (Atf7ip Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 9, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgAtf7ip#1/Cre

Plasmid

#173577

Purpose

Expresses a Atf7ip-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Atf7ip (Atf7ip Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

May 9, 2022

Availability

Academic Institutions and Nonprofits only

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KTK_095

Plasmid

#180524

Purpose

dCas9 KTK compatible plasmid. Contains dCas9 and lacZ dropout region with flanking D1.1 overhangs for insertion of gRNA expression assembly

Depositor

Tom Ellis

Article

Goosens et al ACS Synth Biol. 2021 Dec 17;10(12):3422-

Type

Empty backbone

Expression

Bacterial

Available Since

April 14, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArhgap35#2/Cre

Plasmid

#173570

Purpose

Expresses a Arhgap35-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arhgap35 (Grlf1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

April 13, 2022

Availability

Academic Institutions and Nonprofits only

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Lenti-sgArhgap35#1/Cre

Plasmid

#173569

Purpose

Expresses a Arhgap35-targeting gRNA and Cre-recombinase

Depositor

Charles Swanton

Article

Cai et al Cancer Discov. 2021 Feb 19. pii: 2159-82

Insert

gRNA targeting Arhgap35 (Grlf1 Mouse)

Use

CRISPR, Cre/Lox, and Lentiviral

Available Since

April 13, 2022

Availability

Academic Institutions and Nonprofits only

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px458-AMBRA1 #3

Plasmid

#172607

Purpose

Expresses gRNA #3 against AMBRA1 and Cas9 from S. pyogenes with 2A-EGFP

Depositor

Michele Pagano

Article

Simoneschi et al Nature. 2021 Apr;592(7856):789-793. doi:

Insert

gRNA against AMBRA1 (AMBRA1 Human)

Use

CRISPR

Expression

Mammalian

Promoter

U6

Available Since

Aug. 20, 2021

Availability

Academic Institutions and Nonprofits only

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Human CRISPR Poison Exon Knockout Library

Pooled Library

#138084

Purpose

Targets 3' splice sites with paired gRNAs. Induces skipping of poison cassette exons and matching upstream constitutive exons. Compare loss of a constitutive coding exon with loss of a poison exon.

Depositor

Robert Bradley

Article

Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

Species

Homo sapiens

Use

CRISPR and Lentiviral

Available Since

March 6, 2020

Availability

Academic Institutions and Nonprofits only
MKC131_CCR5(SFFV-synEPOR-2A-YFP)

Plasmid

#232412

Purpose

AAV production plasmid for SFFV(synEPOR) vector from Figs. 2-3 that mediates HDR at CCR5 locus using CCR5 gRNA. YFP is followed by BGH polyA. AAV genome is flanked by AAV2 ITRs.

Depositor

Kyle Cromer

Article

Shah et al Nat Commun. 2025 Jan 29;16(1):1140. doi:

Insert

Truncated Erythropoietin Receptor (EPOR Human)

Use

AAV

Expression

Mammalian

Available Since

April 18, 2025

Availability

Academic Institutions and Nonprofits only

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MKC175_HBA1reg(synEPOR)

Plasmid

#232413

Purpose

AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank H+C15BA1 cassette. HAs are ~400bp each.

Depositor

Kyle Cromer

Article

Shah et al Nat Commun. 2025 Jan 29;16(1):1140. doi:

Insert

Truncated Erythropoietin Receptor (EPOR Human)

Use

AAV

Expression

Mammalian

Available Since

April 18, 2025

Availability

Academic Institutions and Nonprofits only

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lentiGuide-chr20-49345720-gRNA1

Plasmid

#232623

Purpose

Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

Depositor

Claes Wadelius

Article

Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

Insert

S. pyogenes sgRNA cassette

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

April 11, 2025

Availability

Academic Institutions and Nonprofits only

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lentiGuide-chr20-49345720-gRNA2

Plasmid

#232624

Purpose

Lentiviral plasmid expressing gRNA targeting the enhancer region in Chr20:49345720 (hg38) locus with lentiGuide-Hygro-eGFP (Addgene #99375) as backbone.

Depositor

Claes Wadelius

Article

Christensen et al Eur Heart J. 2025 Apr 10:ehaf213. doi: 1

Insert

S. pyogenes sgRNA cassette

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

hU6

Available Since

April 11, 2025

Availability

Academic Institutions and Nonprofits only

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