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We narrowed to 8,392 results for: crispr grnas

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Showing: 8361 - 8380 of 8392 results

  1. KRD22_HBA1(HBA1reg-HBB-longHAs)

    Plasmid
    #232403
    Purpose
    AAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bp
    Depositor
    Kyle Cromer, Matthew Porteus
    Article
    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10
    Inserts
    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Human Hemoglobin Subunit Beta (HBB Human)
    Expression
    Mammalian
    Available Since
    April 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    232403-plasmid-map-sequence-id-466149

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  7. BARBEKO sgRNA library

    Pooled Library
    #174163
    Purpose
    Cytosine base editors for genome-scale knockout screens in human cells. Targets gene start codons, splice sites, or introduces premature termination codons.
    Depositor
    Wensheng Wei
    Article
    Xu et al Nat Biotechnol. 2021 Jun 21. pii: 10.103
    Expression
    Mammalian
    Species
    Homo sapiens
    Use
    CRISPR and Lentiviral
    Available Since
    Aug. 31, 2021
    Availability
    Academic Institutions and Nonprofits only

  8. TUNEYALI Kit

    Plasmid Kit
    #1000000255
    Purpose
    Regulate gene expression by combining gRNA constructs targeting natural promoters and insertion of synthetic promoters in Yarrowia lipolytica.
    Depositor
    Irina Borodina
    Application
    Cloning and Synthetic Biology, Genome Editing
    Vector Type
    Yeast Expression
    Editing Type
    CRISPR
    Cloning Type
    Golden Gate
    Available Since
    April 28, 2025
    Availability
    Academic Institutions and Nonprofits only

  10. CIRTS-YTHDF2-Malat1

    Plasmid
    #216858
    Purpose
    CIRTS RNA targeting system for targeted knockdown of m6A-containing Malat1 at the synapse. CIRTS-YTHDF2-Calm3 and Malat1 gRNA is expressed under human Syn1 and U6 promoter, respectively.
    Depositor
    Timothy Bredy
    Article
    Madugalle et al J Neurosci. 2023 Oct 25;43(43):7084-7100
    Insert
    CIRTS-YTHDF2-Calm3-U6-Malat1 gRNA
    Use
    Lentiviral
    Tags
    GFP
    Expression
    Mammalian
    Promoter
    Syn1, U6
    Available Since
    Aug. 29, 2024
    Availability
    Academic Institutions and Nonprofits only
    216858-plasmid-map-sequence-id-443348

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  11. CIRTS-FTO-Malat1

    Plasmid
    #216860
    Purpose
    CIRTS RNA targeting system for targeted removal of m6A on Malat1 at the synapse. CIRTS-FTO-Calm3 and Malat1 gRNA is expressed under human Syn1 and U6 promoter, respectively.
    Depositor
    Timothy Bredy
    Article
    Madugalle et al J Neurosci. 2023 Oct 25;43(43):7084-7100
    Insert
    CIRTS-FTO-Calm3-U6-Malat1 gRNA
    Use
    Lentiviral
    Expression
    Mammalian
    Promoter
    Syn1, U6
    Available Since
    July 15, 2024
    Availability
    Academic Institutions and Nonprofits only
    216860-plasmid-map-sequence-id-434854

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  19. KRD9_HBA1(HBA1reg-HBB)

    Plasmid
    #232402
    Purpose
    AAV production plasmid for HBA1 UTRs vector from Fig. 3 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank HBA1 cassette. HAs are ~400bp each.
    Depositor
    Kyle Cromer, Matthew Porteus
    Article
    Cromer et al Nat Med. 2021 Apr;27(4):677-687. doi: 10
    Insert
    Hemoglobin Subunit Alpha 1 (HBA1 Human)
    Use
    AAV
    Expression
    Mammalian
    Available Since
    April 18, 2025
    Availability
    Academic Institutions and Nonprofits only
    232402-plasmid-map-sequence-id-462746

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Showing: 8361 - 8380 of 8392 results