We narrowed to 29,554 results for: des.2

1. FH1-PNGT#2-mCherry

   Plasmid

   #164099

   Purpose

   Fluorescent reporter for genetic tracing of proneural Glioblastoma cell-state.

   Depositor

   Gaetano Gargiulo

   Article

   Schmitt et al Cancer Discov. 2021 Mar;11(3):754-777. d

   Insert

   PNGT#2-mCherry
   

   Use

   Lentiviral and Synthetic Biology

   Available Since

   March 11, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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2. lentiCRISPR v2-sgNCKAP1-2

   Plasmid

   #210134

   Purpose

   knock out NCKAP1 in mammalian cells

   Depositor

   Boyi Gan

   Article

   Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

   Insert

   Nck-associated protein 1 (NCKAP1 Human)
   

   Use

   CRISPR

   Available Since

   Nov. 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pSpCas9_BB_2A-GFP_MAPRE1-gRNA#2

   Plasmid

   #107727

   Purpose

   Knock out of EB1 in human cells by CRISPR/Cas9

   Depositor

   Torsten Wittmann

   Article

   van Haren et al Nat Cell Biol. 2018 Jan 29. pii: 10.1038

   Insert

   MAPRE1 gRNA #1 (targets Exon 1) (MAPRE1 Human)
   

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   April 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti-SwitchON-sgCh2-2

   Plasmid

   #199637

   Purpose

   Tamoxifen-inducible expression of sgRNA control targeting intergenic region

   Depositor

   William Hahn

   Article

   So et al JCI Insight. 2022 Oct 10;7(19):e158755.

   Insert

   N/A
   

   Use

   Lentiviral

   Available Since

   June 2, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. SIN40C.TRE.dTomato.miR-125b-2.PGK.sfGFP.P2A.Tet3G

   Plasmid

   #169315

   Purpose

   Doxycycline-inducible expression of miR-125b-2 with dTomato as reporter fluorescent protein

   Depositor

   Jan-Henning Klusmann

   Article

   Alejo-Valle et al Blood. 2021 Sep 27. pii: S0006-4971(21)0

   Insert

   miR-125b-2 (MIR125B2 Human)
   

   Use

   Lentiviral

   Tags

   dTomato

   Promoter

   TRE

   Available Since

   Sept. 22, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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6. pcDNA5FRT/TO PP1gamma-2*Strep

   Plasmid

   #113506

   Purpose

   Expresses dual Strep-tagged PP1gamma in mammalian cells

   Depositor

   Hemmo Meyer

   Article

   Weith et al Mol Cell. 2018 Oct 11. pii: S1097-2765(1

   Insert

   PP1gamma (PPP1CC Human)
   

   Tags

   Strep-Strep

   Expression

   Mammalian

   Available Since

   Oct. 11, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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7. pLG1-puro-sgATL2-2

   Plasmid

   #109009

   Purpose

   CRISPRi knockdown of targeted gene (to be used with Addgene #102244 or other dCas9-KRAB constructs)

   Depositor

   Jacob Corn

   Article

   Liang et al J Cell Biol. 2018 Aug 24. pii: jcb.20180

   Insert

   ATL2-sgRNA #2 (ATL2 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   mU6 promoter

   Available Since

   Aug. 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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8. FUS LC 4S->A#2

   Plasmid

   #226604

   Purpose

   4 serines to alanine at residue positions 70, 84, 89, 95

   Depositor

   Nicolas Fawzi

   Article

   Wake et al Nat Chem Biol. 2025 Jul;21(7):1076-1088.

   Insert

   FUS LC 4S->A#2 (FUS Human)
   

   Tags

   6His

   Expression

   Bacterial

   Mutation

   4 serines to alanine in sequence position subset …

   Promoter

   T7

   Available Since

   July 1, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLentiCRISPR v2-sgCBS-2

   Plasmid

   #230082

   Purpose

   Crispr knock out human CBS gene

   Depositor

   Xingguo Zhu

   Article

   Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

   Insert

   CBS (CBS Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Available Since

   Jan. 10, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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10. pLentiCRISPR v2-sgL2HGDH-2

    Plasmid

    #230084

    Purpose

    Crispr knock out human L2HGDH gene

    Depositor

    Xingguo Zhu

    Article

    Xi et al Commun Biol. 2025 Jan 6;8(1):15. doi: 10

    Insert

    L2HGDH (L2HGDH Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Jan. 10, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3.1 TREK-2(S156C)

    Plasmid

    #224770

    Purpose

    In vitro transcription for Oocyte expression of 1 TREK-2(S156C)

    Depositor

    Dan Minor

    Article

    Deal et al Cell Chem Biol. 2024 Jul 18;31(7):1305-1

    Insert

    Potassium channel subfamily member 10 (Kcnk10 Mouse)
    

    Use

    In vitro transcription for oocyte expression

    Mutation

    S156C

    Promoter

    T7

    Available Since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. lentiCRISPR v2-sgWAVE2-2

    Plasmid

    #210136

    Purpose

    knock out WAVE2 in mammalian cells

    Depositor

    Boyi Gan

    Article

    Liu et al Nat Cell Biol. 2023 Mar;25(3):404-414. d

    Insert

    Actin-binding protein WASF2 (WASF2 Human)
    

    Use

    CRISPR

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pLV_dCas9-KRAB_sgSTK4i_#2 (PuroR)

    Plasmid

    #209774

    Purpose

    CRISPRi for STK4

    Depositor

    Michael Wehr

    Article

    Ma et al Cell Signal. 2024 Jan;113:110917. doi: 1

    Insert

    dCas9-KRAB, sgSTK4i (STK4 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Available Since

    Nov. 8, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pXPR_003 sgINTS12 guide 2

    Plasmid

    #193607

    Purpose

    INTS12 knockout

    Depositor

    William Hahn

    Article

    Hagel et al Cancer Res. 2022 Dec 22:CAN-22-2245. doi

    Insert

    sgINTS12 guide 2 (INTS12 Human)
    

    Use

    Lentiviral

    Available Since

    Jan. 3, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pX330A-Yap1-E1-#2

    Plasmid

    #171519

    Purpose

    deletion of a genomic locus in Yap1 gene

    Depositor

    Hans Schöler

    Article

    Kagiwada et al Development. 2021 Oct 15;148(20). pii: 2

    Insert

    Yap1 (Yap1 Mouse)
    

    Use

    CRISPR

    Expression

    Mammalian

    Available Since

    Nov. 9, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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16. SIN40C.SFFV.mTagBFP2.miR-125b-2

    Plasmid

    #169311

    Purpose

    Constitutive overexpression of miR-125b-2 with mTagBFP2 as a reporter fluorescent protein

    Depositor

    Jan-Henning Klusmann

    Article

    Alejo-Valle et al Blood. 2021 Sep 27. pii: S0006-4971(21)0

    Insert

    miR-125b-2 (MIR125B2 Human)
    

    Use

    Lentiviral

    Promoter

    SFFV

    Available Since

    Sept. 22, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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17. pcDNA-HisA-HOXC6-2

    Plasmid

    #110365

    Purpose

    Mammalian expression of HisA-tagged HOXC6-2

    Depositor

    Carlos Moreno

    Article

    Ramachandran et al Oncogene. 2005 Jan 6;24(1):188-98. doi:

    Insert

    HOXC6 (HOXC6 Human)
    

    Tags

    HIS

    Expression

    Mammalian

    Mutation

    short isoform

    Available Since

    March 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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18. PCRII apoA-IVb.2

    Plasmid

    #121904

    Purpose

    Plasmid for making zebrafish apoA-IVb.2 in situ probe

    Depositor

    Steven Farber

    Article

    Otis et al Dis Model Mech. 2015 Mar;8(3):295-309. d

    Insert

    Apoa4b.2 (apoa4b.2 Zebrafish)
    

    Use

    Unspecified

    Available Since

    May 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLG1-puro-sgATL1-2

    Plasmid

    #109006

    Purpose

    CRISPRi knockdown of targeted gene (to be used with Addgene #102244 or other dCas9-KRAB constructs)

    Depositor

    Jacob Corn

    Article

    Liang et al J Cell Biol. 2018 Aug 24. pii: jcb.20180

    Insert

    ATL1-sgRNA #2 (ATL1 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Promoter

    mU6 promoter

    Available Since

    Aug. 22, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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20. pSicoR (EGFP) shPnky-2

    Plasmid

    #79142

    Purpose

    Stable expression of shRNA targeting mouse Pnky. The shRNA (and EGFP) can be excised by the addition of Cre

    Depositor

    Daniel Lim

    Article

    Ramos et al Cell Stem Cell. 2015 Apr 2;16(4):439-47.

    Insert

    shPnky-2 (Gm30731 Mouse)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Promoter

    U6 for the shRNA and CMV for EGFP

    Available Since

    June 29, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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