We narrowed to 21 results for: des.2

1. Mode #2 Library (NEDD4-2 WW2 domain)

   Pooled Library

   #111708

   Purpose

   Encodes NEDD4-2 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

   Depositor

   Jesse Rinehart

   Article

   Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

   Expression

   Bacterial

   Species

   Homo sapiens

   Available Since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

2. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 2

   Pooled Library

   #168777

   Purpose

   Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

3. Mode #2 Library (14-3-3σ)

   Pooled Library

   #111706

   Purpose

   Encodes 14-3-3σ and human phosphopeptides fused to split mCherry for Hi-P

   Depositor

   Jesse Rinehart

   Article

   Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

   Expression

   Bacterial

   Species

   Homo sapiens

   Available Since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

4. Mode #2 Library (14-3-3β)

   Pooled Library

   #111705

   Purpose

   Encodes 14-3-3β and human phosphopeptides fused to split mCherry for Hi-P

   Depositor

   Jesse Rinehart

   Article

   Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

   Expression

   Bacterial

   Species

   Homo sapiens

   Available Since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

5. Mode #2 Library (NEDD4 WW2 domain)

   Pooled Library

   #111707

   Purpose

   Encodes NEDD4 WW2 domain and human phosphopeptides fused to split mCherry for Hi-P

   Depositor

   Jesse Rinehart

   Article

   Barber et al Nat Biotechnol. 2018 Aug;36(7):638-644.

   Expression

   Bacterial

   Species

   Homo sapiens

   Available Since

   Dec. 1, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Mouse genome-wide lentiviral CRISPR gRNA library version 2

   Pooled Library

   #67988

   Purpose

   Mouse genome-wide CRISPR guide RNA library V2. (pKLV2-U6gRNA5(MouseV2)-PGKpuro2ABFP-W)

   Depositor

   Kosuke Yusa

   Article

   Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

   Species

   Homo sapiens, Mus musculus, and Synthetic

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

7. SARS-CoV-2 Spike (S) Ectodomain Library A

   Pooled Library

   #157971

   Purpose

   Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Bacterial and Yeast

   Species

   Sars-cov-2

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

8. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 2 (positions 437-527)

   Pooled Library

   #174296

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

9. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 2 (positions 437-527)

   Pooled Library

   #174294

   Purpose

   This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 2, positions 437-527) were mutated to every other amino acid.

   Depositor

   Timothy Whitehead

   Article

   Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

   Expression

   Yeast

   Available Since

   Sept. 13, 2021

   Availability

   Academic Institutions and Nonprofits only

10. SARS-CoV-2 Spike (S) Ectodomain Library C

    Pooled Library

    #157973

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

11. SARS-CoV-2 Spike (S) Ectodomain Library B

    Pooled Library

    #157972

    Purpose

    Encodes Spike ectodomain mutations that stabilize 'up' prefusion conformation

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Bacterial and Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

12. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library 1

    Pooled Library

    #168776

    Purpose

    Pooled library expressing barcoded SARS-CoV-2 RNA Binding Domain mutations

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Species

    Sars-cov-2

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

13. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library N501Y Tile 1 (positions 333-436)

    Pooled Library

    #174295

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD N501Y variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

14. SARS-CoV-2 Spike (S) Receptor Binding Domain (RBD) library E484K Tile 1 (positions 333-436)

    Pooled Library

    #174293

    Purpose

    This library contains mutations to SARS-CoV-2 Spike RBD E484K variant in which all surface exposed residues on S RBD (Tile 1, positions 333-436) were mutated to every other amino acid.

    Depositor

    Timothy Whitehead

    Article

    Francino-Urdaniz et al Cell Rep. 2021 Aug 31;36(9):109627. doi:

    Expression

    Yeast

    Available Since

    Sept. 13, 2021

    Availability

    Academic Institutions and Nonprofits only

15. Green monkey (Chlorocebus sabaeus) sgRNA library

    Pooled Library

    #178284

    Purpose

    Genome-wide CRISPR screening library targeting 20,991 genes in C. sabaeus, 84,963 total gRNAs

    Depositor

    John Doench, David Root

    Article

    Wei et al Cell. 2021 Jan 7;184(1):76-91.e13. doi:

    Expression

    Mammalian

    Species

    Chlorocebus sabaeus (african green monkey)

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 23, 2021

    Availability

    Academic Institutions and Nonprofits only

16. pLCKO2::TKOv3

    Pooled Library

    #125517

    Purpose

    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

    Depositor

    Jason Moffat

    Article

    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Aug. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

17. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

    Pooled Library

    #159392

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

18. Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

    Pooled Library

    #159393

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

19. Mouse Validation (mVAL) CRISPR Library

    Pooled Library

    #159391

    Purpose

    Pooled CRISPR library targets core intrinsic immune evasion genes

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

20. Humagne Set D

    Pooled Library

    #172651

    Purpose

    Set D contains best-ranked guides 2 and 3.

    Depositor

    John Doench, David Root

    Article

    DeWeirdt et al Nat Biotechnol. 2020 Jul 13. pii: 10.103

    Expression

    Mammalian

    Available Since

    Nov. 10, 2021

    Availability

    Academic Institutions and Nonprofits only