We narrowed to 10,125 results for: Uty

1. pLentiX1-[TRE3G-FXN-P2A-mRuby2(miRE.FF4)-TS.FF4x1-bGH]-EFS-rtTA-P2A-mGL-WPRE

   Plasmid

   #235305

   Purpose

   Lentiviral expression of ComMAND closed-loop circuit regulating FXN-P2A-mRuby2 (therapeutically relevant gene)

   Depositor

   Kate Galloway

   Article

   Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

   Insert

   FXN-P2A-mRuby2 (FXN Human)
   

   Use

   Lentiviral and Synthetic Biology

   Expression

   Mammalian

   Promoter

   TRE3G (3rd-generation Tet system)

   Available Since

   May 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pLentiX1-[TRE3G-EGFP-FMRP-bGH]-EFS-rtTA-P2A-mRuby2-WPRE

   Plasmid

   #235306

   Purpose

   Lentiviral expression of ComMAND base gene regulating EGFP-FMRP (therapeutically relevant gene)

   Depositor

   Kate Galloway

   Article

   Love et al Cell Syst. 2025 Apr 22:101269. doi: 10.1

   Insert

   EGFP-Fmr1 (Fmr1 Mouse)
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   FLAG

   Expression

   Mammalian

   Promoter

   TRE3G (3rd-generation Tet system)

   Available Since

   May 14, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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3. pcDNA3.1-DDR1-F866Y-V5/HIS

   Plasmid

   #236009

   Purpose

   expression of the F866Y kinase defective mutant variant of human DDR1 that might be associated with lung Adenocarcinoma

   Depositor

   Pavel Krejčí

   Article

   Gudernova et al Elife. 2017 Feb 15;6. pii: e21536. doi:

   Insert

   human DDR1-F866Y receptor tyrosine kinase, full length (DDR1 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   F866Y substitution

   Promoter

   CMV

   Available Since

   April 22, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLL5.0_shRNAHsCavin1_MmCavin1_EGFP

   Plasmid

   #229689

   Purpose

   Lentiviral expression of shRNA targeting Cavin1 + reconstitution of mouse Cavin1 (Cavin1 rescue)

   Depositor

   Alpha Yap

   Article

   Brooks et al Mol Biol Cell. 2023 Nov 1;34(12):ar120.

   Inserts

   shRNA for hCavin1 (CAVIN1 Human)
   mCavin1 (Cavin1 Mouse)
   

   Use

   Lentiviral

   Tags

   EGFP

   Promoter

   LTR viral promoter

   Available Since

   Jan. 29, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-CMV-GFP-LA

   Plasmid

   #206197

   Purpose

   Expresses GFP-tagged human Lamin-A protein by the constitutive CMV promoter in mice

   Depositor

   Yuxuan Guo

   Article

   Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

   Insert

   Lmna (LMNA )
   

   Use

   AAV

   Tags

   GFP

   Promoter

   CMV

   Available Since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. TR01F/hFGFR3-G380R-V5

   Plasmid

   #214908

   Purpose

   for PiggyBac mediated integration and stable expression of hFGFR3-G380R variant that is associated with Achondroplasia

   Depositor

   Pavel Krejčí

   Article

   Kimura et al Sci Transl Med. 2021 May 5;13(592):eaba4

   Insert

   FGFR3 (FGFR3 Human)
   

   Tags

   V5/His

   Expression

   Mammalian

   Mutation

   G380R substitution

   Promoter

   truncated CMV promoter

   Available Since

   April 5, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. CILK1-R272Q

   Plasmid

   #214911

   Purpose

   expression of the mutant variant of CILK1

   Depositor

   Pavel Krejčí

   Article

   Paige Taylor et al Hum Mol Genet. 2016 Sep 15;25(18):3998-4

   Insert

   CILK1 (CILK1 Human)
   

   Tags

   Myc-FLAG

   Expression

   Mammalian

   Mutation

   R272Q substitution

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. CILK1-E80K

   Plasmid

   #214910

   Purpose

   expression of the mutant variant of CILK1

   Depositor

   Pavel Krejčí

   Article

   Paige Taylor et al Hum Mol Genet. 2016 Sep 15;25(18):3998-4

   Insert

   CILK1 (CILK1 Human)
   

   Tags

   Myc-FLAG

   Expression

   Mammalian

   Mutation

   E80K substitution

   Promoter

   CMV

   Available Since

   March 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. VC-Y705F+K49R-STAT3

   Plasmid

   #203721

   Purpose

   Expresses the PTM-resistant, double mutant Y705F+K49R - STAT3 fused to the 158-238 fragment of Venus in mammalian cells

   Depositor

   Federico Herrera

   Article

   Diallo et al Cell Oncol (Dordr). 2023 Dec 27. doi: 10

   Insert

   STAT3 tagged with VC (aa 158-238) (STAT3 Human)
   

   Tags

   VC (aa 158-238) for bimolecular fluorescence comp…

   Expression

   Mammalian

   Mutation

   Y705F+K49R substitutions

   Promoter

   CMV

   Available Since

   Dec. 21, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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10. VC-Y705F+K685R-STAT3

    Plasmid

    #203722

    Purpose

    Expresses the PTM-resistant, double mutant Y705F+K685R - STAT3 fused to the 158-238 fragment of Venus in mammalian cells

    Depositor

    Federico Herrera

    Article

    Diallo et al Cell Oncol (Dordr). 2023 Dec 27. doi: 10

    Insert

    STAT3 tagged with VC (aa 158-238) (STAT3 Human)
    

    Tags

    VC (aa 158-238) for bimolecular fluorescence comp…

    Expression

    Mammalian

    Mutation

    Y705F+K685R substitutions

    Promoter

    CMV

    Available Since

    Dec. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA5-FRT/TO-mNeonGreen-BRD4-p300(H*IT)

    Plasmid

    #204698

    Purpose

    This plasmid allows for inducible expression of engineered BRD4-p300(H*IT) fusion tagged with mNeonGreen, in mammalian cells.

    Depositor

    Michael Rosen

    Article

    Kosno et al Sci Rep. 2023 Jul 24;13(1):11907. doi: 1

    Insert

    BRD4-p300(H*IT) (BRD4, EP300 Human)
    

    Tags

    mNeonGreen

    Expression

    Mammalian

    Mutation

    D1399Y substitution in p300

    Promoter

    CMV

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. Myc-Nix-S212D

    Plasmid

    #197515

    Purpose

    Mammalian expression of myc-tagged human Nix with an aspartic acid substitution of serine-212. Based on Myc-Nix (#100795)

    Depositor

    Joseph Gordon

    Article

    da Silva Rosa et al Autophagy. 2021 Sep;17(9):2257-2272. doi

    Insert

    BCL2 interacting protein 3 like (BNIP3L Human)
    

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Serine 212 changed to aspartic acid

    Promoter

    CMV

    Available Since

    March 2, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. Myc-Bnip3-T181A

    Plasmid

    #197556

    Purpose

    Mammalian expression of myc-tagged mouse Bnip3 with an alanine substitution of threonine-181. Based on Myc-Bnip3FL (#100796)

    Depositor

    Joseph Gordon

    Article

    Martens et al Cell Death Dis. 2021 Nov 26;12(12):1105.

    Insert

    BCL2 Interacting Protein 3 (Bnip3 Mouse)
    

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Threonine 181 changed to alanine

    Promoter

    CMV

    Available Since

    March 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. Myc-Nix-S212A

    Plasmid

    #197514

    Purpose

    Mammalian expression of myc-tagged human Nix with an alanine substitution of serine-212. Based on Myc-Nix (#100795)

    Depositor

    Joseph Gordon

    Article

    da Silva Rosa et al Autophagy. 2021 Sep;17(9):2257-2272. doi

    Insert

    BCL2 interacting protein 3 like (BNIP3L Human)
    

    Tags

    Myc

    Expression

    Mammalian

    Mutation

    Serine 212 changed to alanine

    Promoter

    CMV

    Available Since

    March 1, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pMXS-IRES-BLAST flag-CAD G-Loop1

    Plasmid

    #188128

    Purpose

    Expresses C-terminal flag-tagged human CAD G-Loop1 in mammalian cells

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    TCC -> AGT silent mutations at nt439-441 elimi…

    Available Since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pMXS-IRES-BLAST flag-CAD G-Loop2

    Plasmid

    #188129

    Purpose

    Expresses C-terminal flag-tagged human CAD G-Loop2 in mammalian cells

    Depositor

    Richard Possemato

    Article

    Shin et al Nat Metab. 2023 Feb 6. doi: 10.1038/s422

    Insert

    CAD (CAD Human)
    

    Use

    Retroviral

    Tags

    Flag tag

    Expression

    Mammalian

    Mutation

    TCC -> AGT silent mutations at nt439-441 elimi…

    Available Since

    Feb. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLKO_S.V5.FLAG_NGFR

    Plasmid

    #158337

    Purpose

    Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

    Depositor

    Brian Brown

    Article

    Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

    Insert

    Pro-Code Tagged human dNGFR (NGFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    S.V5.FLAG

    Mutation

    Truncation of the signaling domain

    Promoter

    EF1a

    Available Since

    Sept. 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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18. pLKO_S.V5.NWS_NGFR

    Plasmid

    #158338

    Purpose

    Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

    Depositor

    Brian Brown

    Article

    Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

    Insert

    Pro-Code Tagged human dNGFR (NGFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    S.V5.NWS

    Mutation

    Truncation of the signaling domain

    Promoter

    EF1a

    Available Since

    Sept. 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pLKO_S.V5.AU1_NGFR

    Plasmid

    #158340

    Purpose

    Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

    Depositor

    Brian Brown

    Article

    Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

    Insert

    Pro-Code Tagged human dNGFR (NGFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    S.V5.AU1

    Mutation

    Truncation of the signaling domain

    Promoter

    EF1a

    Available Since

    Sept. 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLKO_S.V5.VSVg_NGFR

    Plasmid

    #158341

    Purpose

    Protein Barcode (Pro-Code) for vector/cell tracking. Contains U6 trRNA cassette for sgRNA cloning. Enables phenotypic CRISPR screens at a single cell resolution (using cytometry).

    Depositor

    Brian Brown

    Article

    Wroblewska et al Cell. 2018 Nov 1;175(4):1141-1155.e16. d

    Insert

    Pro-Code Tagged human dNGFR (NGFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    S.V5.VSVg

    Mutation

    Truncation of the signaling domain

    Promoter

    EF1a

    Available Since

    Sept. 3, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge