We narrowed to 34,080 results for: MUT

1. pEGFP C3-Lats1-PY1+2 mutant

   Plasmid

   #19054

   Depositor

   Marius Sudol

   Article

   Oka et al J Biol Chem. 2008 Oct 10;283(41):27534-2

   Insert

   Large tumor suppressor kinase 1, N mutant (LATS1 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   PY1 mutant, (Tyrosine 376 changed to Alanine) and…

   Available Since

   Sept. 8, 2008

   Availability

   Academic Institutions and Nonprofits only

2. pT7-EGFP-C1-HsNXF-1-5xmut_O

   Plasmid

   #147116

   Purpose

   Mammalian Expression of HsNxf-1-5xmut

   Depositor

   Elisa Izaurralde

   Article

   Teplova et al Nat Struct Mol Biol. 2011 Aug 7;18(9):99

   Insert

   HsNxf-1-5xmut (NXF1 Human)
   

   Expression

   Mammalian

   Mutation

   See Depositor Comments Below

   Available Since

   March 16, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pET30a-His6-ABP-LOXCATmut

   Plasmid

   #139972

   Purpose

   A control for His6-ABP-LOXCAT where LOX is catalytically dead (mutations H265A and R268A)

   Depositor

   Vamsi Mootha

   Article

   Patgiri et al Nat Biotechnol. 2020 Jan 13. pii: 10.103

   Insert

   A fusion of lactate oxidase from A. viridans and catalase from E. coli
   

   Tags

   His6

   Expression

   Bacterial

   Mutation

   Mutation in H265A and R268A in LOX (used original…

   Promoter

   T7

   Available Since

   Sept. 16, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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4. pFLEX-m-cyclin D1 -T286A mutant

   Plasmid

   #86792

   Purpose

   mammalian expression of cyclin D1 T286A mutant

   Depositor

   Martine Roussel, Charles Sherr

   Article

   Matsushime et al Cell. 1991 May 17;65(4):701-13.

   Insert

   cyclin D1 (Ccnd1 Mouse)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   T286A

   Available Since

   Feb. 14, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCGN-ELK-1 Ets mut

   Plasmid

   #27157

   Purpose

   For mammalian expression of human Elk-1 with an HA tag and a mutation in the Ets DNA binding domain

   Depositor

   Ron Prywes

   Article

   Lee et al J Biol Chem. 2010 Jul 16. 285(29):22036-

   Insert

   ELK1 (ELK1 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   R62E/R65E/Y66D

   Available Since

   Dec. 22, 2010

   Availability

   Academic Institutions and Nonprofits only

6. pGEX-EZH2-T487A mutant

   Plasmid

   #28061

   Depositor

   Mien-Chie Hung

   Article

   Wei et al Nat Cell Biol. 2011 Jan . 13(1):87-94.

   Insert

   EZH2 (EZH2 Human)
   

   Tags

   GST

   Expression

   Bacterial

   Mutation

   T487A

   Available Since

   June 6, 2011

   Availability

   Academic Institutions and Nonprofits only

7. pTCF176 HLA-A*02:01 (CD8 mut)

   Plasmid

   #180459

   Purpose

   E. coli expression of soluble MHC protein

   Depositor

   John Altman

   Insert

   HLA-A*02:01 (CD8 mut)
   

   Tags

   BSP41

   Expression

   Bacterial

   Mutation

   D227K, T228A, replacement of transmembrane domain…

   Available Since

   Feb. 24, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. PTEN-mut (negative control)

   Plasmid

   #86646

   Purpose

   expression of control shRNA

   Depositor

   Jaime Modiano

   Article

   Lin et al Mol Cancer. 2007 Feb 14;6:16.

   Insert

   PTEN (control)
   

   Use

   RNAi

   Expression

   Mammalian

   Promoter

   H1

   Available Since

   June 20, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLL5.0 hCortKD-Flcortmut3YD EGFP

   Plasmid

   #187264

   Purpose

   Lentiviral expression of shRNA targeting Cortactin + reconstitution of Cortactin3YD mutant

   Depositor

   Alpha Yap

   Article

   Liang et al Nat Commun. 2017 Oct 5;8(1):790. doi: 10

   Insert

   Cortactin (CTTN Human)
   

   Use

   Lentiviral

   Tags

   EGFP

   Mutation

   3YD (Y412, Y470, Y486)

   Promoter

   U6, 5'LTR

   Available Since

   Sept. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pcDNA3 myc card9 mutant

    Plasmid

    #16254

    Depositor

    William Kaelin

    Article

    Yang et al Mol Cell. 2007 Oct 12. 28(1):15-27.

    Insert

    card9 mutant (CARD9 Human)
    

    Tags

    myc

    Expression

    Mammalian

    Mutation

    S528A, T531A, T533A, S536A

    Available Since

    Nov. 21, 2007

    Availability

    Academic Institutions and Nonprofits only

11. pmCherry-C1-INPP4B C842A mutant

    Plasmid

    #161996

    Purpose

    Mammalian expression vector containing a phosphatase dead mutant of INPP4B (C842A). Also contains mCherry tag

    Depositor

    David Bryant

    Article

    Roman-Fernandez et al Nat Commun. 2018 Nov 28;9(1):5041. doi:

    Insert

    INPP4B (INPP4B Human)
    

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    C842A

    Available Since

    Dec. 3, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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12. pGL3-basic-FTO promoter_Mut

    Plasmid

    #108923

    Purpose

    The core promoter region of FTO with mutant CEBPA binding sites was inserted into pGL3 basic vector

    Depositor

    Jianjun Chen

    Article

    Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

    Insert

    FTO (FTO Human)
    

    Tags

    NA

    Expression

    Mammalian

    Mutation

    NA

    Available Since

    May 30, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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13. pRK5-mEGFP-RAX-MUT

    Plasmid

    #194573

    Purpose

    Mammalian Expression of mEGFP-RAX Mutant (S222Rfs*63) Fusion Protein

    Depositor

    Denes Hnisz

    Article

    Mensah et al Nature. 2023 Feb;614(7948):564-571. doi:

    Insert

    RAX (RAX Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    S222Rfs*63

    Available Since

    Feb. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pRK5-mEGFP-MYOD1-MUT

    Plasmid

    #194571

    Purpose

    Mammalian Expression of mEGFP-MYOD1 Mutant (R188Pfs*90) Fusion Protein

    Depositor

    Denes Hnisz

    Article

    Mensah et al Nature. 2023 Feb;614(7948):564-571. doi:

    Insert

    MYOD1 (MYOD1 Human)
    

    Tags

    mEGFP

    Expression

    Mammalian

    Mutation

    R188Pfs*90

    Available Since

    Feb. 22, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. S10A mutant of H3S10ph biosensor

    Plasmid

    #120810

    Purpose

    FRET biosensor. Eliminating the H3 Serine 10 phosphorylation site in H3S10ph biosensor to abolish the detection capability

    Depositor

    Yingxiao Wang

    Article

    Peng et al Proc Natl Acad Sci U S A. 2018 Nov 26. p

    Insert

    Mouse histone H3-CFP-FHA2-histone H3 peptide (1-14aa) S10A-YFP
    

    Expression

    Mammalian

    Mutation

    Serine 10 is mutated to Alanine, and Threonine 3,…

    Promoter

    CMV

    Available Since

    Feb. 12, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. Mutant Human Cortactin-GFP

    Plasmid

    #71365

    Purpose

    mammalian expression of mutant human Cortactin-GFP

    Depositor

    Alpha Yap

    Article

    Han et al J Biol Chem. 2014 Mar 14;289(11):7764-75

    Insert

    cortactin (CTTN Human)
    

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    silent mutation present at 72nd nucleotide

    Promoter

    CMV

    Available Since

    Nov. 17, 2015

    Availability

    Academic Institutions and Nonprofits only

17. c-myc promoter (TBE 1m/2m - mut)

    Plasmid

    #16596

    Depositor

    Bert Vogelstein

    Article

    He et al Science. 1998 Sep 4. 281(5382):1509-12.

    Insert

    c-myc promoter (TBE 1m/2m mut) (MYC Human)
    

    Use

    Luciferase

    Tags

    luciferase

    Expression

    Mammalian

    Mutation

    Tcf-4 binding elements (TBEs) mutated

    Available Since

    March 21, 2008

    Availability

    Academic Institutions and Nonprofits only

18. ERalpha (Y537S mutant)-pcw107-V5

    Plasmid

    #64634

    Purpose

    when used to produce lentivirus, express physiological levels of insert

    Depositor

    David Sabatini, Kris Wood

    Article

    Martz et al Sci Signal. 2014 Dec 23;7(357):ra121. do

    Insert

    ESR1 (transcript variant 1) (ESR1 Human)
    

    Use

    Lentiviral

    Tags

    V5

    Mutation

    Y537S

    Promoter

    PGK

    Available Since

    May 12, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pLL5.0 mCherry-hCortKD-Flcortmut3YD

    Plasmid

    #187266

    Purpose

    Lentiviral expression of shRNA targeting Cortactin + reconstitution of Cortactin3YD mutant

    Depositor

    Alpha Yap

    Article

    Liang et al Nat Commun. 2017 Oct 5;8(1):790. doi: 10

    Insert

    Cortactin (CTTN Human)
    

    Use

    Lentiviral

    Tags

    mCherry

    Mutation

    3YD (Y412, Y470, Y486)

    Promoter

    U6, 5'LTR

    Available Since

    Sept. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLL5.0 hCortKD-Flcortmut3YF mCherry

    Plasmid

    #187265

    Purpose

    Lentiviral expression of shRNA targeting Cortactin + reconstitution of Cortactin3YF mutant

    Depositor

    Alpha Yap

    Article

    Liang et al Nat Commun. 2017 Oct 5;8(1):790. doi: 10

    Insert

    Cortactin (CTTN Human)
    

    Use

    Lentiviral

    Tags

    mCherry

    Mutation

    3YF (Y412, Y470, Y486)

    Promoter

    U6, 5'LTR

    Available Since

    Sept. 26, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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