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pAAVS1-Neo-CAG-M2rtTA-H2BmNeon (donorAB-mNeon)

Plasmid

#85799

Purpose

donorAB-Neon targeting vector for human AAVS1 locus; knock-in of Dox controlled H2BGFP

Depositor

Roland Friedel

Article

Tejero et al EBioMedicine. 2019 Apr 2. pii: S2352-396

Insert

PPP1R12C (PPP1R12C Human)

Use

Human targeting

Mutation

homology arms for knock-in into first intron

Available Since

April 26, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-FGFR1

Plasmid

#116740

Purpose

Lentiviral expression of FGFR1

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

FGFR1 (FGFR1 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-BRAF

Plasmid

#116719

Purpose

Lentiviral expression of BRAF

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

BRAF (BRAF Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-KDR

Plasmid

#116754

Purpose

Lentiviral expression of KDR

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

KDR (KDR Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-ESR1-Y537N

Plasmid

#116373

Purpose

Lentiviral expression of ESR1 Y537N

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ESR1 (ESR1 Human)

Use

Lentiviral

Mutation

Y537N

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-EGFR-E746_T751delinsA

Plasmid

#116246

Purpose

Lentiviral expression of EGFR E746_T751delinsA

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

E746_T751delinsA

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-XPO1-E571K

Plasmid

#116708

Purpose

Lentiviral expression of XPO1 E571K

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

XPO1 (XPO1 Human)

Use

Lentiviral

Mutation

E571K

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pDisplay-iSeroSnFR

Plasmid

#128484

Purpose

Fluorescent reporter for serotonin (mammalian expression, membrane localization tag)

Depositor

Lin Tian

Article

Unger et al Cell. 2020 Dec 12. pii: S0092-8674(20)31

Insert

iSeroSnFR

Tags

Ig-kappa leader, Myc, PDGFR + enhanced ER export,…

Expression

Mammalian

Promoter

CMV

Available Since

Jan. 4, 2021

Availability

Academic Institutions and Nonprofits only

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pHAGE-XPO1-R749Q

Plasmid

#116709

Purpose

Lentiviral expression of XPO1 R749Q

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

XPO1 (XPO1 Human)

Use

Lentiviral

Mutation

R749Q

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-EGFR-T790M

Plasmid

#116310

Purpose

Lentiviral expression of EGFR T790M

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

T790M

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-GUCY2C

Plasmid

#116749

Purpose

Lentiviral expression of GUCY2C

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

GUCY2C (GUCY2C Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pAAVS1-Neo-CAG-M2rtTA-H2BGFP (donor AB)

Plasmid

#85798

Purpose

donorAB targeting vector for human AAVS1 locus; knock-in of Dox controlled H2BGFP expression system

Depositor

Roland Friedel

Article

Tejero et al EBioMedicine. 2019 Apr 2. pii: S2352-396

Insert

PPP1R12C (PPP1R12C Human)

Use

Human targeting

Mutation

homology arms for knock-in into first intron

Available Since

March 4, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-ALK

Plasmid

#116712

Purpose

Lentiviral expression of ALK

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ALK (ALK Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pGH020 sgp53

Plasmid

#227947

Purpose

sgRNA targeting p53, GFP, neomycin resistance, Mammalian expression, Mouse targeting, lentiviral, CRISPR

Depositor

Laura Attardi

Article

Boutelle et al Cell Death Differ. 2025 Apr 22. doi: 10.

Insert

Tp53 (Trp53 Mouse)

Use

CRISPR and Lentiviral

Expression

Mammalian

Promoter

human U6

Available Since

April 24, 2025

Availability

Academic Institutions and Nonprofits only

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pHAGE-EPHA2-G391R

Plasmid

#116320

Purpose

Lentiviral expression of EPHA2 G391R

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EPHA2 (EPHA2 Human)

Use

Lentiviral

Mutation

G391R

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-BCL2

Plasmid

#116717

Purpose

Lentiviral expression of BCL2

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

BCL2 (BCL2 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-ESR1-Y537C

Plasmid

#116372

Purpose

Lentiviral expression of ESR1 Y537C

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ESR1 (ESR1 Human)

Use

Lentiviral

Mutation

Y537C

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

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pHAGE-GNAS

Plasmid

#116748

Purpose

Lentiviral expression of GNAS

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

GNAS (GNAS Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ESR1-E380Q

Plasmid

#116368

Purpose

Lentiviral expression of ESR1 E380Q

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ESR1 (ESR1 Human)

Use

Lentiviral

Mutation

E380Q

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ESR1-L536Q

Plasmid

#116369

Purpose

Lentiviral expression of ESR1 L536Q

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ESR1 (ESR1 Human)

Use

Lentiviral

Mutation

L536Q

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-hSyn-GRAB_DA1m

Plasmid

#113049

Purpose

express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1m in neurons

Depositor

Yulong Li

Article

Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

Has Service

AAV9

Insert

GPCR activation based DA sensor GRAB_DA1m (DRD2 Human)

Use

AAV

Promoter

hSyn

Available Since

Aug. 3, 2018

Availability

Academic Institutions and Nonprofits only

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pLV-shFMR1-mCherry

Plasmid

#222963

Purpose

Make lentivirus to knock down human FMR1 gene

Depositor

Xinyu Zhao

Article

Guo et al Nat Commun. 2023 Jun 26;14(1):3801. doi:

Insert

FMR1 shRNA (FMR1 Human)

Use

Lentiviral

Available Since

Oct. 17, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-FGFR4

Plasmid

#116743

Purpose

Lentiviral expression of FGFR4

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

FGFR4 (FGFR4 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-CDK6

Plasmid

#116725

Purpose

Lentiviral expression of CDK6

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

CDK6 (CDK6 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-NRAS-Q61K

Plasmid

#116444

Purpose

Lentiviral expression of NRAS Q61K

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NRAS (NRAS Human)

Use

Lentiviral

Mutation

Q61K

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-hSyn-GRAB_DA1h

Plasmid

#113050

Purpose

express the genetically-encoded fluorescent dopamine(DA) sensor GRAB_DA1h in neurons

Depositor

Yulong Li

Article

Sun et al Cell. 2018 Jul 12;174(2):481-496.e19. do

Has Service

AAV Retrograde and AAV9

Insert

GPCR activation based DA sensor GRAB_DA1h (DRD2 Human)

Use

AAV

Promoter

hSyn

Available Since

Aug. 2, 2018

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-NRAS

Plasmid

#116767

Purpose

Lentiviral expression of NRAS

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

NRAS (NRAS Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-FLT4

Plasmid

#116745

Purpose

Lentiviral expression of FLT4

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

FLT4 (FLT4 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
peSCBE3-NG-Hypa

Plasmid

#218165

Purpose

This plasmid harbors the base editor eSCBE3-NG-Hypa along with an sgRNA cloning cassette, facilitating high-efficiency and high-fidelity cytosine base editing at targets bearing NG PAM in Streptomyces

Depositor

Yuhui Sun

Article

Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

Inserts

escbe3-NG-Hypa
a programmable sgRNA cloning cassette

Use

CRISPR; Sgrna transcription

Expression

Bacterial

Mutation

Mutation in the portion of deaminase hAPOBEC3A : …

Promoter

rpsL promoter

Available Since

May 13, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-EGFR-G719S

Plasmid

#116256

Purpose

Lentiviral expression of EGFR G719S

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

G719S

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-FGFR2-N549K

Plasmid

#116380

Purpose

Lentiviral expression of FGFR2 N549K

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

FGFR2 (FGFR2 Human)

Use

Lentiviral

Mutation

N549K

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-BAI3

Plasmid

#116716

Purpose

Lentiviral expression of BAI3

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

BAI3 (BAI3 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-EGFR-H773_V774insNPH

Plasmid

#116262

Purpose

Lentiviral expression of EGFR H773_V774insNPH

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

H773_V774insNPH

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
PCDH-Mut-ALKBH5-3xFLAG

Plasmid

#203737

Purpose

Overexpression of ALKBH5-Mut

Depositor

Jianjun Chen

Article

Shen et al Cell Stem Cell. 2020 Jul 2;27(1):64-80.e

Insert

ALKBH5 (ALKBH5 Human)

Use

Lentiviral

Tags

3xFLAG

Expression

Mammalian

Mutation

Enzyme Inactive Mutation (H226A)

Available Since

July 31, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-IDH1

Plasmid

#116751

Purpose

Lentiviral expression of IDH1

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

IDH1 (IDH1 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-Tnnt2-GFP-LA

Plasmid

#206198

Purpose

Expresses GFP-tagged Lamin-A specifically in cardiomyocytes by the Tnnt2 promoter

Depositor

Yuxuan Guo

Article

Sun et al JACC Basic Transl Sci. 2024 Aug 21;9(11)

Insert

Lmna (LMNA Human)

Use

AAV

Tags

GFP

Promoter

Tnnt2

Available Since

Aug. 23, 2024

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-PIK3CA-R88Q

Plasmid

#116538

Purpose

Lentiviral expression of PIK3CA R88Q

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3CA (PIK3CA Human)

Use

Lentiviral

Mutation

R88Q

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-PIK3CA-C420R

Plasmid

#116457

Purpose

Lentiviral expression of PIK3CA C420R

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

PIK3CA (PIK3CA Human)

Use

Lentiviral

Mutation

C420R

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-EGFR-G719C

Plasmid

#116254

Purpose

Lentiviral expression of EGFR G719C

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

G719C

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
CS2 Flag-Smad2 (3A)

Plasmid

#101763

Purpose

Expresses SMAD2 (3A) in mammalian cells

Depositor

Yuh-Shan Jou

Article

Yeh et al Nat Cell Biol. 2018 Apr;20(4):479-491. d

Insert

SMAD2 (SMAD2 Human)

Tags

Flag

Expression

Mammalian

Mutation

Three Ser to Ala mutations in the phosphorylation…

Promoter

CMV

Available Since

Oct. 20, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-CAG-iSeroSnFR-Nlgn

Plasmid

#128485

Purpose

Fluorescent reporter for serotonin (dendrite localization tag)

Depositor

Lin Tian

Article

Unger et al Cell. 2020 Dec 12. pii: S0092-8674(20)31

Has Service

AAV9

Insert

iSeroSnFR

Use

AAV

Tags

Full-length neuroligin, Ig-kappa leader, and cpsf…

Expression

Mammalian

Promoter

CAG

Available Since

Dec. 23, 2020

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ARAF

Plasmid

#116713

Purpose

Lentiviral expression of ARAF

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ARAF (ARAF Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-CDH1

Plasmid

#116722

Purpose

Lentiviral expression of CDH1

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

CDH1 (CDH1 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ERBB3-V104M

Plasmid

#116363

Purpose

Lentiviral expression of ERBB3 V104M

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ERBB3 (ERBB3 Human)

Use

Lentiviral

Mutation

V104M

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-POU4F2

Plasmid

#116776

Purpose

Lentiviral expression of POU4F2

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

POU4F2 (POU4F2 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-EGFR-M766_A767insAI

Plasmid

#116279

Purpose

Lentiviral expression of EGFR M766_A767insAI

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

EGFR (EGFR Human)

Use

Lentiviral

Mutation

M766_A767insAI

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-ERBB4

Plasmid

#116736

Purpose

Lentiviral expression of ERBB4

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

ERBB4 (ERBB4 Human)

Use

Lentiviral

Mutation

WT

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge
pAAV-mTubb3

Plasmid

#87116

Purpose

AAV backbone plasmid including GFP knock-in donor and Tubb3gRNA for HITI

Depositor

Juan Belmonte

Article

Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

Insert

U6-mTubb3sgRNA-GFP-EF1a-mCherryKASH-hGHpA

Use

AAV and CRISPR

Available Since

March 22, 2017

Availability

Academic Institutions and Nonprofits only

Enlarge
6xHis-MBP-BrCas12b-FNLDTA

Plasmid

#195340

Purpose

Expresses Engineered BrCas12b in Bacteria

Depositor

Piyush Jain

Article

Nguyen et al Cell Rep Med. 2023 May 16;4(5):101037. d

Insert

BrCas12b

Use

CRISPR and Synthetic Biology

Tags

6xHis Tag and MBP, TEV cleavage site, 6x His Tag

Expression

Bacterial

Mutation

F208W, N524V, L795I, D868V, T874S, A1015E

Promoter

T7 Promoter

Available Since

May 5, 2023

Availability

Academic Institutions and Nonprofits only

Enlarge
pHAGE-RAC1-P29S

Plasmid

#116650

Purpose

Lentiviral expression of RAC1 P29S

Depositor

Gordon Mills, Kenneth Scott

Article

Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

Insert

RAC1 (RAC1 Human)

Use

Lentiviral

Mutation

P29S

Available Since

March 14, 2019

Availability

Academic Institutions and Nonprofits only

Enlarge

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