We narrowed to 2,556 results for: neurod

1. pBacMam2-DiEx-LIC-N-flag_huntingtin_full-length_Q73

   Plasmid

   #111724

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q73 (polyQ repeat)

   Promoter

   CMV and P10

   Available Since

   Nov. 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-syn-AICD-IRES-hrGFP

   Plasmid

   #107548

   Purpose

   high transduction efficiency AAV-mediated synapsin promoter-dependent expression of AICD (last 50 amino acids of APP) and IRES-mediated co-expression of hrGFP

   Depositor

   Hélène Marie

   Article

   Pousinha et al Elife. 2017 Jul 6;6. doi: 10.7554/eLife.

   Insert

   AICD (APP Human)
   

   Use

   AAV

   Mutation

   None

   Promoter

   human synapsin

   Available Since

   May 1, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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3. AP-APP

   Plasmid

   #196706

   Purpose

   Expresses APP695 with a biotin Acceptor Peptide tag at N-terminal for single molecule tracking and other measusers in mammalian cells

   Depositor

   Martino Calamai

   Article

   Capitini et al iScience. 2023 Apr 11;26(5):106611. doi:

   Insert

   Amyloid Precursor Protein 695 isoform (APP Human)
   

   Tags

   AP, Avitag and HA

   Expression

   Mammalian

   Available Since

   April 26, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pBacMam2-DiEx-LIC-C-flag_huntingtin_full-length_Q73

   Plasmid

   #111728

   Purpose

   Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

   Depositor

   Cheryl Arrowsmith

   Article

   Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

   Insert

   HTT (HTT Human)
   

   Use

   Baculovirus expression

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   Q73 (polyQ repeat)

   Promoter

   CMV and P10

   Available Since

   Oct. 31, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-CMVenh synapsin-intron-aSYNUCLEIN A53T

   Plasmid

   #227004

   Purpose

   AAV transfer plasmid encoding the human A53T mutant α-SYN under the control of the CMVie enhanced synapsin1 promoter

   Depositor

   Veerle Baekelandt

   Article

   Van der Perren et al J Vis Exp. 2016 Feb 28;(108):53670. doi:

   Insert

   alpha synuclein A53T mutant (SNCA Human, Synthetic)
   

   Use

   AAV

   Mutation

   A53T

   Promoter

   CMVenh synapsin

   Available Since

   Oct. 31, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. ATM gRNA (BRDN0001149033)

   Plasmid

   #77531

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ATM

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ATM (ATM Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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7. pD649-HAsp-CSF1R-COMP5AP-AviTag-9xHis

   Plasmid

   #157447

   Purpose

   Mammalian expression of cell-surface protein extracellular domain fused to COMP5AP-AviTag-9xHis. Protein is secreted from cells.

   Depositor

   Chris Garcia

   Article

   Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

   Insert

   CSF1R (CSF1R Human)
   

   Tags

   COMP5AP-AviTag-9xHis

   Expression

   Mammalian

   Promoter

   CMV/SP6

   Available Since

   March 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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8. ATM gRNA (BRDN0001146099)

   Plasmid

   #77530

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human ATM

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   ATM (ATM Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. pBABE-Tau-cYFP

   Plasmid

   #92205

   Purpose

   Retroviral overexpression vector for α-Syn/Tau bimolecular fluorescence complementation (BiFC)

   Depositor

   Huda Zoghbi

   Article

   Rousseaux et al Elife. 2016 Oct 25;5. pii: e19809. doi:

   Insert

   MAPT (MAPT Human)
   

   Use

   Retroviral

   Tags

   YFP(156-239)

   Expression

   Mammalian

   Available Since

   Aug. 7, 2017

   Availability

   Academic Institutions and Nonprofits only

10. pDEST-Tol2-PA2-CMV-AB-mCh

    Plasmid

    #160435

    Purpose

    Expresses human Amyloid Beta-mCherry in Zebrafish

    Depositor

    Nicholas Tolwinski

    Article

    Kaur et al Bio Protoc. 2020 Dec 5;10(23):e3856. doi

    Insert

    Human Amyloid Beta peptide (1-42) (APP Zebrafish, Human)
    

    Use

    Zebrafish expression

    Tags

    mCherry

    Promoter

    CMV

    Available Since

    Oct. 6, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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11. IP3 receptor, type 1 scFv [L24/1]

    Plasmid

    #206755

    Purpose

    Mammalian Expression of IP3 receptor, type 1 scFV. Derived from hybridoma L24/1 scFv.

    Depositor

    James Trimmer

    Article

    Mitchell et al Sci Rep. 2023 Sep 27;13(1):16200. doi: 1

    Insert

    IP3 receptor, type 1 (Rattus norvegicus) recombinant scFV (Itpr1 Mouse)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Jan. 23, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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12. pCS2plus-mCerulean 156-239-GGGS-TDP-43 M337V

    Plasmid

    #162618

    Purpose

    Allows for transcription of mCerulean fluorophore half fused to mutant TDP-43-M337V for injection into zebrafish embryos for BiFC assays

    Depositor

    Marco Morsch

    Article

    Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

    Insert

    TARDBP (TARDBP Human)
    

    Expression

    Mammalian

    Mutation

    M337V

    Available Since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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13. TH0901-pOCC177-FUS-wt_opt(Nhe)

    Plasmid

    #221885

    Purpose

    Shuttle vector for baculovirus production, using FlashBac bacmid

    Depositor

    Anthony Hyman

    Article

    Wang et al Cell. 2018 Jul 26;174(3):688-699.e16. do

    Insert

    FUS (FUS Human)
    

    Tags

    6xHis-MBP-PreScission and TEV-SNAP-tag

    Expression

    Insect

    Mutation

    wt

    Promoter

    PH promoter

    Available Since

    July 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pBABE-Tau-nYFP

    Plasmid

    #92204

    Purpose

    Retroviral overexpression vector for Tau bimolecular fluorescence complementation (BiFC)

    Depositor

    Huda Zoghbi

    Article

    Rousseaux et al Elife. 2016 Oct 25;5. pii: e19809. doi:

    Insert

    MAPT (MAPT Human)
    

    Use

    Retroviral

    Tags

    YFP(1-155)

    Expression

    Mammalian

    Available Since

    Aug. 7, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pBacMam2-DiEx-LIC-N-flag_huntingtin_full-length_Q79

    Plasmid

    #111725

    Purpose

    Baculovirus transfer vector for expression of huntingtin protein in insect and mammalian cellscells as well as in mammalian cells

    Depositor

    Cheryl Arrowsmith

    Article

    Harding et al J Biol Chem. 2019 Apr 26;294(17):6986-70

    Insert

    HTT (HTT Human)
    

    Use

    Baculovirus expression

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    Q79 (polyQ repeat)

    Promoter

    CMV and P10

    Available Since

    Oct. 31, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pCS2plus-mCerulean 156-239-GGGS-TDP-43

    Plasmid

    #162617

    Purpose

    Allows for transcription of mCerulean fluorophore half fused to TDP-43 for injection into zebrafish embryos for BiFC assays

    Depositor

    Marco Morsch

    Article

    Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

    Insert

    TARDBP (TARDBP Human)
    

    Expression

    Mammalian

    Available Since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pSicoR Dnmt1

    Plasmid

    #12166

    Purpose

    Cre-regulated lentiviral shRNA vector. Cre addition causes both EGFP and shRNA to be recombined out of the construct, turning OFF Dnmt1 shRNA expression.

    Depositor

    Tyler Jacks

    Article

    Ventura et al Proc Natl Acad Sci U S A. 2004 Jul 13. 1

    Insert

    Dnmt1 shRNA (Dnmt1 Mouse)
    

    Use

    Cre/Lox, Lentiviral, and RNAi

    Expression

    Mammalian

    Mutation

    EGFP is expressed from this plasmid as a marker, …

    Available Since

    June 30, 2006

    Availability

    Academic Institutions and Nonprofits only

18. pCS2plus-mVenus1-155-GGGS-TDP43 M337V

    Plasmid

    #162612

    Purpose

    Allows for transcription of mVenus fluorophore half fused to mutant TDP-43-M337V for injection into zebrafish embryos for BiFC assays

    Depositor

    Marco Morsch

    Article

    Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

    Insert

    TARDBP (TARDBP Human)
    

    Expression

    Mammalian

    Mutation

    M337V

    Available Since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCS2plus-mVenus1-155-I152L-GGGS-TDP-43

    Plasmid

    #162614

    Purpose

    Allows for transcription of improved mVenus I152L fluorophore half fused to TDP-43 for injection into zebrafish embryos for BiFC assays

    Depositor

    Marco Morsch

    Article

    Don et al Mol Neurobiol. 2021 May;58(5):2061-2074.

    Insert

    TARDBP (TARDBP Human)
    

    Expression

    Mammalian

    Available Since

    June 10, 2021

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pD649-HAsp-ERBB4-Fc(DAPA)-AviTag-6xHis

    Plasmid

    #156931

    Purpose

    Mammalian expression of cell-surface protein extracellular domain fused to Fc(DAPA)-Avi-6xHis. Protein is secreted from cells.

    Depositor

    Chris Garcia

    Article

    Wojtowicz et al Cell. 2020 Aug 20;182(4):1027-1043.e17.

    Insert

    ERBB4 (ERBB4 Human)
    

    Tags

    Fc(DAPA)-AviTag-6xHis

    Expression

    Mammalian

    Mutation

    Fc region of human IgG contains D265A and P329A m…

    Promoter

    CMV/SP6

    Available Since

    Jan. 20, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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