We narrowed to 18,349 results for: MUT

1. pmcherry α-catenin M319G/R326E

   Plasmid

   #178648

   Purpose

   express α-catenin with M319G/R326E mutation

   Depositor

   Daniel Conway

   Article

   Bejar-Padilla et al Mol Biol Cell. 2022 Aug 3:mbcE22020071.

   Insert

   α-catenin (CTNNA1 Human)
   

   Tags

   mcherry

   Expression

   Mammalian

   Mutation

   M319G/R326E

   Available Since

   Aug. 8, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-FLEXfrt-SaCas9-U6-sgGria2

   Plasmid

   #124868

   Purpose

   Mutagenesis of Gria2

   Depositor

   Larry Zweifel

   Article

   Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

   Insert

   Gria2 (Gria2 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Available Since

   May 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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3. cytosolic moPrP (3F4)

   Plasmid

   #1321

   Depositor

   Susan Lindquist

   Article

   Ma et al Proc Natl Acad Sci U S A 2001 Dec 18;98(

   Insert

   PrP (Prnp Mouse)
   

   Expression

   Mammalian

   Mutation

   N-term truncation (to make gene cytosolic), vario…

   Available Since

   Jan. 21, 2005

   Availability

   Academic Institutions and Nonprofits only

4. pRCPam

   Plasmid

   #195861

   Purpose

   Encodes chromogenic protein (CP) with nonsense mutation resulting in amber stop codon at amino acid 62. CP inducible with rhamnose in amber suppressor strains.

   Depositor

   Gregory Phillips

   Article

   DeWolf et al J Microbiol Biol Educ. 2023 Oct 25;24(3)

   Insert

   Amber Chromogenic Protein on pRCPam plasmid
   

   Expression

   Bacterial

   Mutation

   Gln62X

   Available Since

   Feb. 8, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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5. pCDNA3-V5-PTPN14-PPxY

   Plasmid

   #61006

   Purpose

   Expresses human PTPN14 (PPxY domain mutant) in mammalian cells, N-terminus V5 tag

   Depositor

   Jianmin Zhang

   Article

   Wilson et al J Biol Chem. 2014 Aug 22;289(34):23693-7

   Insert

   PTPN14 PPxY mutation (PTPN14 Human)
   

   Tags

   V5 tag

   Expression

   Mammalian

   Mutation

   PPxY mutation

   Promoter

   CMV

   Available Since

   Dec. 4, 2014

   Availability

   Academic Institutions and Nonprofits only

6. pAAV-FLEXfrt-SaCas9-U6-sgGrin1

   Plasmid

   #124865

   Purpose

   Mutagenesis of Grin1

   Depositor

   Larry Zweifel

   Article

   Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

   Insert

   Grin1 (Grin1 Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Available Since

   May 6, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. Lox-stop-Lox p53 R270H

   Plasmid

   #14853

   Depositor

   Tyler Jacks

   Article

   Olive et al Cell. 2004 Dec 17. 119(6):847-60.

   Insert

   p53 R270H (Trp53 Mouse)
   

   Use

   Cre/Lox

   Tags

   Lox-STOP-lox

   Expression

   Mammalian

   Mutation

   Contact mutant R270H. (Murine p53 codon 270 corre…

   Available Since

   April 27, 2007

   Availability

   Academic Institutions and Nonprofits only

8. pCDH-EF1-FHC-POLQ-S1977P

   Plasmid

   #64876

   Purpose

   lentiviral expression of human POLQ S1977P mutant (mimicks the chaos1 mutation)

   Depositor

   Richard Wood

   Article

   Yousefzadeh et al PLoS Genet. 2014 Oct 2;10(10):e1004654.

   Insert

   POLQ (POLQ Human)
   

   Use

   Lentiviral

   Tags

   FLAG and HA

   Expression

   Mammalian

   Mutation

   S1977P, mimicking the chaos1 mutation

   Promoter

   EF1alpha

   Available Since

   July 11, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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9. LentiV_Neo_SIK3_CR_T221A

   Plasmid

   #108107

   Purpose

   Lentiviral expression plasmid of human SIK3 cDNA (CRISPR-resistant silent mutation & TA mutation at LKB1 phosphorylation site) with neomycin resistance gene

   Depositor

   Christopher Vakoc

   Article

   Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

   Insert

   SIK3 (SIK3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Mutation

   change guanine 501 to cytosine (silent mutation),…

   Promoter

   EFS promoter

   Available Since

   May 8, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-FLEXfrt-SaCas9-U6-sgGabrg1

    Plasmid

    #124870

    Purpose

    Mutagenesis of Gabrg1

    Depositor

    Larry Zweifel

    Article

    Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

    Insert

    Gabrg1 (Gabrg1 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Available Since

    May 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3-FLAG-MTOR-D2512H

    Plasmid

    #69017

    Purpose

    activating MTOR mutation

    Depositor

    David Sabatini

    Article

    Grabiner et al Cancer Discov. 2014 May;4(5):554-63. doi

    Insert

    MTOR-D2512H (MTOR Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    change Aspartate 2512 to Histidine

    Available Since

    Dec. 16, 2015

    Availability

    Academic Institutions and Nonprofits only

12. pCI-Neo-PTPRT (R632X)

    Plasmid

    #16629

    Depositor

    Bert Vogelstein

    Article

    Wang et al Science. 2004 May 21. 304(5674):1164-6.

    Insert

    PTPRT R632X (PTPRT Human)
    

    Expression

    Mammalian

    Mutation

    truncated R632X mutant

    Available Since

    March 10, 2008

    Availability

    Academic Institutions and Nonprofits only

13. pAAV-FLEX-SaCas9-U6-sgGabrg1

    Plasmid

    #124856

    Purpose

    Mutagenesis of Gabrg1

    Depositor

    Larry Zweifel

    Article

    Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

    Insert

    Gabrg1 (Gabrg1 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Available Since

    May 6, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pcDNA3-ULK2-K39I

    Plasmid

    #97076

    Purpose

    Expresses mutant ULK2 in mammalian cells

    Depositor

    Pasquale Vito

    Article

    Scudiero et al Cell Death Dis. 2017 Feb 23;8(2):e2627.

    Insert

    ULK2 (ULK2 Human)
    

    Tags

    FLAG

    Expression

    Mammalian

    Mutation

    changed Lysine 39 to Isoleucine

    Promoter

    CMV

    Available Since

    Aug. 16, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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15. pEGFP_E1770Q-talin1 (1-2541)

    Plasmid

    #166121

    Purpose

    For expression of full-length mouse talin-1 carrying mutation E1770Q in mammalian cells. Contains C-terminal EGFP tag.

    Depositor

    Vesa Hytönen

    Article

    Azizi et al Sci Rep. 2021 Jan 11;11(1):347. doi: 10.

    Insert

    E1770Q-Talin-1 (Tln1 Mouse)
    

    Use

    Cmv promoter

    Tags

    EGFP

    Expression

    Mammalian

    Mutation

    E1770Q

    Available Since

    April 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCOCK CM-R03

    Plasmid

    #46567

    Purpose

    Mammalian expression plasmid with EGFP expressed from synthetic promoter (random mutagenesis of CMVwt 3' end).

    Depositor

    Clifford Wang

    Article

    Ferreira et al Syst Synth Biol. 2011 Dec;5(3-4):131-8.

    Insert

    CMV mutant promoter
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Mutation

    Mutant version of CMV promoter (refer to Table 1 …

    Available Since

    Sept. 23, 2013

    Availability

    Academic Institutions and Nonprofits only

17. LentiV_Neo_SIK3_CR_T142Q

    Plasmid

    #108109

    Purpose

    Lentiviral expression plasmid of human SIK3 cDNA (CRISPR-resistant silent mutation & gatekeeper mutation) with neomycin resistance gene

    Depositor

    Christopher Vakoc

    Article

    Tarumoto et al Mol Cell. 2018 Feb 28. pii: S1097-2765(1

    Insert

    SIK3 (SIK3 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Mutation

    change guanine 501 to cytosine (silent mutation),…

    Promoter

    EFS promoter

    Available Since

    April 5, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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18. pDual-eGFP(Stop66)

    Plasmid

    #63218

    Purpose

    Expression of a non-sense mutant version of eGFP (dark) in bacteria and in mammalian cells. Could be used as a reporter for gene targeting and recombineering in mammalian cells.

    Depositor

    Richard S Myers

    Article

    Valledor et al IUBMB Life. 2012 Aug;64(8):684-9. doi: 1

    Insert

    His-T7-eGFP(Stop66)
    

    Use

    Lentiviral

    Tags

    T7 and his6

    Expression

    Bacterial and Mammalian

    Mutation

    Changed tyrosine at position 66 with respect to t…

    Promoter

    CMV-EF1α hybrid (CEF)

    Available Since

    April 27, 2015

    Availability

    Academic Institutions and Nonprofits only

19. pCOCK CM-R05

    Plasmid

    #46568

    Purpose

    Mammalian expression plasmid with EGFP expressed from synthetic promoter (random mutagenesis of CMVwt 3' end).

    Depositor

    Clifford Wang

    Article

    Ferreira et al Syst Synth Biol. 2011 Dec;5(3-4):131-8.

    Insert

    CMV mutant promoter
    

    Use

    Synthetic Biology

    Expression

    Mammalian

    Mutation

    Mutant version of CMV promoter (refer to Table 1 …

    Available Since

    Sept. 23, 2013

    Availability

    Academic Institutions and Nonprofits only

20. pAAV-FLEX-SaCas9-U6-sgGabrg3

    Plasmid

    #124858

    Purpose

    Mutagenesis of Gabrg3

    Depositor

    Larry Zweifel

    Article

    Hunker et al Cell Rep. 2020 Mar 24;30(12):4303-4316.e

    Insert

    Gabrg3 (Gabrg3 Mouse)
    

    Use

    AAV, CRISPR, and Mouse Targeting

    Available Since

    May 6, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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