We narrowed to 51,045 results for: ANG

1. pSCBE3-Hypa

   Plasmid

   #218157

   Purpose

   This plasmid harbors the base editor SCBE3-Hypa along with an sgRNA cloning cassette, facilitating high-fidelity cytosine base editing in Streptomyces.

   Depositor

   Yuhui Sun

   Article

   Wang et al Nat Commun. 2024 Jul 7;15(1):5687. doi:

   Inserts

   scbe3-Hypa
   a programmable sgRNA cloning cassette
   

   Use

   CRISPR; Sgrna transcription

   Expression

   Bacterial

   Mutation

   Mutations in the portion of SpCas9 : D10A / N692A…

   Promoter

   rpsL promoter

   Available Since

   May 10, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. Lenti-sgRNA-Cre-GpNLuc-sgmZBP1#3

   Plasmid

   #208389

   Purpose

   Lentiviral vector expressing Cas9, GpNLuc, and sgRNA targeting murine ZBP1#3 gene.

   Depositor

   Gaorav Gupta

   Article

   Cho et al Nature. 2024 Jan 10. doi: 10.1038/s41586

   Insert

   sgZBP1 (Zbp1 Mouse)
   

   Use

   Lentiviral and Luciferase

   Expression

   Mammalian

   Mutation

   WT

   Available Since

   Jan. 11, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. B52_puro_gRNA_3418711_KCNB2

   Plasmid

   #197558

   Purpose

   gRNA targeting upstream region of KCNB2 (site 3418711, control for epigenetic targeting)

   Depositor

   Darius Bägli

   Insert

   upstream KCNB2 promoter gRNA (Kcnb2 Rat)
   

   Use

   Grna with puromycin selection

   Tags

   puromycin resistance cassette under CMV promotion

   Expression

   Mammalian

   Promoter

   U6

   Available Since

   March 27, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pMIR218-2_nt5G>U

   Plasmid

   #174009

   Purpose

   miR218 nt5 point mutation in SLIT3

   Depositor

   Andrew M. Siedlecki

   Article

   Liu et al J Am Soc Nephrol. 2022 Mar;33(3):565-582

   Insert

   SLIT3 (SLIT3, MIR218-2 Human)
   

   Expression

   Mammalian

   Mutation

   NT5 G>U point mutation in SLIT3

   Available Since

   Sept. 6, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. S+Q111R+N122D

   Plasmid

   #167175

   Purpose

   Expresses the full Leptodactylus latrans Na+K+ATPase with ATP1A1-S variant with Q111R and N122D mutations in Sf9 cells

   Depositor

   Susanne Dobler

   Article

   Mohammadi et al Curr Biol. 2021 Jun 21;31(12):2530-2538.

   Inserts

   ATP1A1-S+Q111R+N122D
   ATP1B1
   

   Expression

   Bacterial and Insect

   Mutation

   Changed Q at 111 to R and changed N at 122 to D

   Promoter

   P10 and PH

   Available Since

   Feb. 7, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pHAGE-PTH2-L22V

   Plasmid

   #116639

   Purpose

   Lentiviral expression of PTH2 L22V

   Depositor

   Kenneth Scott, Gordon Mills

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PTH2 (PTH2 Human)
   

   Use

   Lentiviral

   Mutation

   L22V

   Available Since

   April 9, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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7. pHAGE-PTH2

   Plasmid

   #116781

   Purpose

   Lentiviral expression of PTH2

   Depositor

   Kenneth Scott, Gordon Mills

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PTH2 (PTH2 Human)
   

   Use

   Lentiviral

   Mutation

   WT

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. pHAGE-NOTCH2NL

   Plasmid

   #116766

   Purpose

   Lentiviral expression of NOTCH2NL

   Depositor

   Kenneth Scott, Gordon Mills

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   NOTCH2NL (NOTCH2NLA Human)
   

   Use

   Lentiviral

   Mutation

   WT

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pHAGE-TBC1D3B-R162Q

   Plasmid

   #116694

   Purpose

   Lentiviral expression of TBC1D3B R162Q

   Depositor

   Kenneth Scott, Gordon Mills

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   TBC1D3B (TBC1D3B Human)
   

   Use

   Lentiviral

   Mutation

   R162Q

   Available Since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. pHAGE-WDR12-Q93K

    Plasmid

    #116706

    Purpose

    Lentiviral expression of WDR12 Q93K

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    WDR12 (WDR12 Human)
    

    Use

    Lentiviral

    Mutation

    Q93K

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. pHAGE-TBC1D3B-G164E

    Plasmid

    #116692

    Purpose

    Lentiviral expression of TBC1D3B G164E

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    TBC1D3B (TBC1D3B Human)
    

    Use

    Lentiviral

    Mutation

    G164E

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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12. pHAGE-NOTCH2NL-G137L

    Plasmid

    #116439

    Purpose

    Lentiviral expression of NOTCH2NL G137L

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    NOTCH2NL (NOTCH2NLA Human)
    

    Use

    Lentiviral

    Mutation

    G137L

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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13. pHAGE-NOTCH2NL-Q172_G173delinsHC

    Plasmid

    #116440

    Purpose

    Lentiviral expression of NOTCH2NL Q172_G173delinsHC

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    NOTCH2NL (NOTCH2NLA Human)
    

    Use

    Lentiviral

    Mutation

    Q172_G173delinsHC

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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14. pHAGE-NOTCH2NL-R87M

    Plasmid

    #116441

    Purpose

    Lentiviral expression of NOTCH2NL R87M

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    NOTCH2NL (NOTCH2NLA Human)
    

    Use

    Lentiviral

    Mutation

    R87M

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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15. pHAGE-NOTCH2NL-S165F

    Plasmid

    #116442

    Purpose

    Lentiviral expression of NOTCH2NL S165F

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    NOTCH2NL (NOTCH2NLA Human)
    

    Use

    Lentiviral

    Mutation

    S165F

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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16. pHAGE-OXA1L-L57F

    Plasmid

    #116445

    Purpose

    Lentiviral expression of OXA1L L57F

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    OXA1L (OXA1L Human)
    

    Use

    Lentiviral

    Mutation

    L57F

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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17. pHAGE-OXA1L-P58S

    Plasmid

    #116446

    Purpose

    Lentiviral expression of OXA1L P58S

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    OXA1L (OXA1L Human)
    

    Use

    Lentiviral

    Mutation

    P58S

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pXJ219-pAAV-PB3'IR-U6-gRNA-EF1a-mtagBFP2-KASH-PB5'IR

    Plasmid

    #210525

    Purpose

    AAV piggybac transposon vector, with mtagBFP-KASH reporter and gRNA cloning site. Compatible with 10X 5' gRNA capture technology.

    Depositor

    Xin Jin

    Article

    Zheng et al Cell. 2024 Jun 20;187(13):3236-3248.e21.

    Inserts

    mtagBFP-KASH
    U6-gRNA
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Feb. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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19. pXJ385-pAAV-PB3’IR-U6-gRNA-EF1a-mScarlet-KASH-PB5’IR

    Plasmid

    #224435

    Purpose

    AAV piggybac transposon vector, with mScarlet-KASH reporter and gRNA cloning site. Compatible with 10X 5' gRNA capture technology.

    Depositor

    Xin Jin

    Article

    Zheng et al Cell. 2024 Jun 20;187(13):3236-3248.e21.

    Inserts

    mScarlet-KASH
    U6-gRNA
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Available Since

    Aug. 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. PBAN-tetOn-NKX3.1

    Plasmid

    #238472

    Purpose

    Doxycycline inducible expression of the NKX3.1 transcription factor for mural cell differentiation.

    Depositor

    Juan Melero-Martin

    Article

    Lee et al Nat Commun. 2024 Sep 30;15(1):8392. doi:

    Insert

    NKX3.1 (NKX3-1 Human)
    

    Expression

    Mammalian

    Available Since

    Oct. 15, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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21. pHAGE-RET

    Plasmid

    #116787

    Purpose

    Lentiviral expression of RET

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    RET (RET Human)
    

    Use

    Lentiviral

    Mutation

    WT

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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22. pSLIK MEK5-DD-mRFP1 neo

    Plasmid

    #47548

    Purpose

    Lentiviral expression vector for an inducible mRFP1-tagged constitutively active MEK5 mutant

    Depositor

    Kevin Janes

    Article

    Jensen et al Cell Host Microbe. 2013 Jan 16;13(1):67-

    Insert

    MEK5-DD-mRFP1 (MAP2K5 Human)
    

    Use

    Lentiviral

    Tags

    mRFP

    Expression

    Mammalian

    Mutation

    S311D, T315D

    Available Since

    Aug. 28, 2013

    Availability

    Academic Institutions and Nonprofits only

23. pTubb3-MC

    Plasmid

    #87112

    Purpose

    minicircle parental backbone plasmid including GFP knock-in donor targeting Tubb3 gene and one cutting site for HITI

    Depositor

    Juan Belmonte

    Article

    Suzuki et al Nature. 2016 Dec 1;540(7631):144-149. do

    Insert

    GFP
    

    Use

    CRISPR

    Available Since

    March 31, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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24. PCDH-WT-ALKBH5-3xFLAG

    Plasmid

    #203736

    Purpose

    Overexpression of ALKBH5-WT

    Depositor

    Jianjun Chen

    Article

    Shen et al Cell Stem Cell. 2020 Jul 2;27(1):64-80.e

    Insert

    ALKBH5 (ALKBH5 Human)
    

    Use

    Lentiviral

    Tags

    3xFLAG

    Expression

    Mammalian

    Available Since

    July 28, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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25. pHAGE-B2M

    Plasmid

    #116715

    Purpose

    Lentiviral expression of B2M

    Depositor

    Kenneth Scott, Gordon Mills

    Article

    Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

    Insert

    B2M (B2M Human)
    

    Use

    Lentiviral

    Mutation

    WT

    Available Since

    March 14, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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26. 3` CC: Hygro – H2B-GFP-N – loxP – mScarlet

    Plasmid

    #219565

    Purpose

    3` circularization cassette to induce Cre-mediated circularization of a genomic region flanked by loxP sites with H2B-GFP reconstitution and mScarlet expression from the chromosome

    Depositor

    Andrea Ventura

    Article

    Pradella et al Nature. 2024 Dec 18. doi: 10.1038/s41586

    Insert

    HygroR_2A_H2B-GFP-N_loxP_mScarlet
    

    Use

    Unspecified

    Promoter

    EF-1a

    Available Since

    Nov. 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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27. pXJ220-pAAV-PB3'IR-U6-gRNA-EF1a-GFP-KASH-PB5'IR

    Plasmid

    #213481

    Purpose

    AAV piggybac transposon vector, with GFP-KASH reporter and gRNA cloning site. Compatible with 10X 5' gRNA capture technology.

    Depositor

    Xin Jin

    Article

    Zheng et al Cell. 2024 Jun 20;187(13):3236-3248.e21.

    Inserts

    GFP-KASH
    U6-gRNA
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Feb. 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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28. pWZL-Blast FAP S624A

    Plasmid

    #207402

    Purpose

    Expresses the S624A mutant of FAP (Fibroblast Activation Protein), which shows no protease activity.

    Depositor

    Jing Yang

    Article

    Bukhari et al Cell Rep. 2023 Oct 31;42(10):113302. doi

    Insert

    Fibroblast Activation Protein Alpha (FAP Human)
    

    Use

    Retroviral

    Mutation

    changed Serine 624 to Alanine. It's a protea…

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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29. pWZL-Blast FAP A657S

    Plasmid

    #207403

    Purpose

    Expresses the A657S mutant of FAP (Fibroblast Activation Protein), which shows partial protease activity.

    Depositor

    Jing Yang

    Article

    Bukhari et al Cell Rep. 2023 Oct 31;42(10):113302. doi

    Insert

    Fibroblast Activation Protein Alpha (FAP Human)
    

    Use

    Retroviral

    Mutation

    changed Alanine 657 to Serine. It's an endop…

    Available Since

    Dec. 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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30. gTBEv4

    Plasmid

    #220620

    Purpose

    vector for encoding an engineered glycosylase-based thymine (T) base editor (gTBEv4) driven by EF1a promoter, guide RNAs compatible with SpCas9 driven by hU6, mCherry driven by CBh promoter

    Depositor

    Huawei Tong

    Article

    Tong et al Nat Commun. 2024 Jun 8;15(1):4897. doi:

    Insert

    nSpCas9(Nterm)-XTEN-hUNG2-XTEN-Cas9(Cterm)
    

    Expression

    Mammalian

    Mutation

    hUNG2(del1-88;Y156A,A214T,Q259A,Y284D), SpCas9(D1…

    Promoter

    hU6, EF1a

    Available Since

    June 21, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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