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pLV-TTBL

Plasmid

#115233

Purpose

Lentiviral transfer plasmid for expression of SAD B19 L and mTagBFP2

Depositor

Ian Wickersham

Article

Jin et al Nat Neurosci. 2024 Jan 11. doi: 10.1038/

Insert

mTagBFP2 and rabies virus SAD B19 strain polymerase gene (B19L)

Expression

Mammalian

Available Since

Oct. 19, 2021

Availability

Academic Institutions and Nonprofits only

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pLEX307_PDHA2S291A

Plasmid

#115196

Purpose

Lentiviral transduction and expression of PDHA2S291A into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PDHA2S291A (PDHA2 Human)

Use

Lentiviral

Mutation

p.S291A

Promoter

EF1alpha

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pETM33_Nsp3c_SUD-C

Plasmid

#156471

Purpose

Bacterial expression of Sars-CoV2 Nsp3c_SUD-C protein with His-tag and GST-tag

Depositor

Ylva Ivarsson

Article

Mihalic et al Nat Commun. 2023 Sep 13;14(1):5636. doi:

Insert

Nsp3c_SUD-C (ORF1ab Synthetic)

Tags

His-GST

Expression

Bacterial

Mutation

Gene insert is codon optimized for Ecoli.

Promoter

T7/LacO

Available Since

Aug. 4, 2020

Availability

Academic Institutions and Nonprofits only

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pETM33_Nsp3e_NAB

Plasmid

#156473

Purpose

Bacterial expression of Sars-CoV2 Nsp3e_NAB protein with His-tag and GST-tag

Depositor

Ylva Ivarsson

Article

Mihalic et al Nat Commun. 2023 Sep 13;14(1):5636. doi:

Insert

Nsp3e_NAB (ORF1ab Synthetic, Severe acute respiratory syndrome coronavirus 2)

Tags

His-GST

Expression

Bacterial

Mutation

Gene insert is codon optimized for Ecoli.

Promoter

T7/LacO

Available Since

Aug. 4, 2020

Availability

Academic Institutions and Nonprofits only

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AAV C-terminus ABE8e-V106W targeting Pex1-G844D

Plasmid

#247655

Purpose

AAV genome encoding the C-terminus of ABE8e-V106W editor and Sp sgRNA cassette

Depositor

David Liu

Article

Gao et al Nat Biomed Eng. 2026 Apr 14. doi: 10.103

Insert

C-terminus ABE8e-V106W editor and Pex1-G844D-targeting sgRNA

Use

AAV and CRISPR

Promoter

CBh

Available Since

April 14, 2026

Availability

Academic Institutions and Nonprofits only

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AAV N-terminus ABE8e-V106W targeting Pex1-G844D

Plasmid

#247654

Purpose

AAV genome encoding the N-terminus of ABE8e-V106W editor and Sp sgRNA cassette

Depositor

David Liu

Article

Gao et al Nat Biomed Eng. 2026 Apr 14. doi: 10.103

Insert

N-terminus ABE8e-V106W editor and Pex1-G844D-targeting sgRNA

Use

AAV and CRISPR

Promoter

CBh

Available Since

April 14, 2026

Availability

Academic Institutions and Nonprofits only

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pLEX_307-SOD1E133insTT

Plasmid

#83446

Purpose

Mammalian expression of SOD1E133insTT.

Depositor

Mohan Babu

Article

Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

Insert

SOD1 (SOD1 Human)

Use

Lentiviral

Expression

Mammalian

Mutation

E133insTT (after GA)

Promoter

EF-1α

Available Since

Nov. 9, 2016

Availability

Academic Institutions and Nonprofits only

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pLEX_307-SOD1E133Δ

Plasmid

#83445

Purpose

Mammalian expression of SOD1E133Δ.

Depositor

Mohan Babu

Article

Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

Insert

SOD1 (SOD1 Human)

Use

Lentiviral

Expression

Mammalian

Mutation

E133Δ

Promoter

EF-1α

Available Since

Nov. 9, 2016

Availability

Academic Institutions and Nonprofits only

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pSOD1E133K-AcGFP1

Plasmid

#83442

Purpose

Expresses SOD1E133K in mammalian cells.

Depositor

Mohan Babu

Article

Malty et al Cell Syst. 2017 Nov 7. pii: S2405-4712(1

Insert

SOD1 (SOD1 Human)

Tags

AcGFP1

Expression

Mammalian

Mutation

E133K

Promoter

CMV

Available Since

Nov. 9, 2016

Availability

Academic Institutions and Nonprofits only

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Lentivirus ABE8e-V106W with non-targeting sgRNA

Plasmid

#247668

Purpose

Lentivirus genome encoding ABE8eV106W editor and Sp sgRNA cassette non-targeting control

Depositor

David Liu

Article

Gao et al Nat Biomed Eng. 2026 Apr 14. doi: 10.103

Insert

ABE8e-V106W and non-targeting sgRNA

Use

Lentiviral

Expression

Mammalian

Promoter

EFS

Available Since

April 14, 2026

Availability

Academic Institutions and Nonprofits only

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Lentivirus ABE8e-V106W targeting PEX1-G843D

Plasmid

#247667

Purpose

Lentivirus genome encoding ABE8eV106W editor and Sp sgRNA cassette targeting PEX1-G843D mutation

Depositor

David Liu

Article

Gao et al Nat Biomed Eng. 2026 Apr 14. doi: 10.103

Insert

ABE8e-V106W editor and PEX1-G843D-targeting sgRNA

Use

Lentiviral

Expression

Mammalian

Promoter

EFS

Available Since

April 14, 2026

Availability

Academic Institutions and Nonprofits only

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pENTR223-PARK7H126A

Plasmid

#115180

Purpose

Gateway cloning of PARK7H126A into any destination vector

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7H126A (PARK7 Human)

Use

Gateway cloning into appropriate destination vect…

Mutation

p.H126A

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pENTR223-PARK7E163K

Plasmid

#115181

Purpose

Gateway cloning of PARK7E163K into any destination vector

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7E163K (PARK7 Human)

Use

Gateway cloning into appropriate destination vect…

Mutation

p.E163K

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pLD-puro-Cc-PARK7V51G-VA

Plasmid

#115183

Purpose

Lentiviral transduction and expression of PARK7V51G into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7V51G (PARK7 Human)

Use

Lentiviral

Tags

Versatile affinity tag (2XStreptactin II-6XHis-3X…

Mutation

p.V51G

Promoter

CMV

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pLD-puro-Cc-PARK7C53A-VA

Plasmid

#115184

Purpose

Lentiviral transduction and expression of PARK7C53A into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7C53A (PARK7 Human)

Use

Lentiviral

Tags

Versatile affinity tag (2XStreptactin II-6XHis-3X…

Mutation

p.C53A

Promoter

CMV

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pLD-puro-Cc-PARK7H126A-VA

Plasmid

#115185

Purpose

Lentiviral transduction and expression of PARK7H126A into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7H126A (PARK7 Human)

Use

Lentiviral

Tags

Versatile affinity tag (2XStreptactin II-6XHis-3X…

Mutation

p.H126A

Promoter

CMV

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pLD-puro-Cc-PARK7E163K-VA

Plasmid

#115186

Purpose

Lentiviral transduction and expression of PARK7E163K into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7E163K (PARK7 Human)

Use

Lentiviral

Tags

Versatile affinity tag (2XStreptactin II-6XHis-3X…

Mutation

p.E163K

Promoter

CMV

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pLEX307_PDHA2S291A/S293A

Plasmid

#115198

Purpose

Lentiviral transduction and expression of PDHA2S291A/S293A into any mammalian cell

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PDHA2S291A/S293A (PDHA2 Human)

Use

Lentiviral

Mutation

p.S291A/S293A

Promoter

EF1alpha

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pENTR223-PARK7V51G

Plasmid

#115178

Purpose

Gateway cloning of PARK7V51G into any destination vector

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7V51G (PARK7 Human)

Use

Gateway cloning into appropriate destination vect…

Mutation

p.V51G

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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pENTR223-PARK7C53A

Plasmid

#115179

Purpose

Gateway cloning of PARK7C53G into any destination vector

Depositor

Mohan Babu

Article

Moutaoufik et al iScience. 2019 Sep 4;19:1114-1132. doi:

Insert

PARK7C53A (PARK7 Human)

Use

Gateway cloning into appropriate destination vect…

Mutation

p.C53A

Available Since

March 26, 2021

Availability

Academic Institutions and Nonprofits only

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