We narrowed to 5,690 results for: org

1. pcDNA3.1-GSDMD_D275A

   Plasmid

   #224704

   Purpose

   Expression of mutated Gasdermin D_D275A (GSDMD_D275A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_D275A (GSDMD Human)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   D275A

   Promoter

   CVM

   Available Since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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2. pcDNA3.1-GSDMD_H270A_D275A

   Plasmid

   #224705

   Purpose

   Expression of mutated Gasdermin D_H270A_D275A (GSDMD_D275A) in transfected mammalian cell lines

   Depositor

   Christopher Overall

   Article

   Grin et al Cell Rep. 2024 Dec 24;43(12):115080. doi

   Insert

   GSDMD_Q29A_H270A (GSDMD Human)
   

   Tags

   FLAG

   Expression

   Mammalian

   Mutation

   H270A and D275A

   Promoter

   CMV

   Available Since

   July 2, 2025

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. pMRX-IP-EGFP-PA-BAX(ER, G108V)

   Plasmid

   #233344

   Purpose

   Stable expression of EGFP-LOV2(N538E)-BAX(G108V)-Cyb5a in mammalian cells. The G108V mutation suppresses pore-forming activity of BAX.

   Depositor

   Noboru Mizushima

   Article

   Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

   Inserts

   LOV2 domain of phototropin1
   BAX (BAX Human)
   Cyb5a (Cyb5a Rat)
   

   Use

   Retroviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   BAX(3-171), N-terminus and C-terminus are deleted…

   Available Since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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4. pCAG-MCP-Lbr-V5-mCherry

   Plasmid

   #235093

   Purpose

   Lbr mCherry fusion protein with MCP domain

   Depositor

   Mitchell Guttman

   Article

   Bhat et al Nature. 2024 May;629(8014):1165-1173. do

   Insert

   pCAG-MCP-Lbr-V5-mCherry (LBR Human)
   

   Expression

   Mammalian

   Promoter

   CAG

   Available Since

   May 7, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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5. pMRX-IP-EGFP-PA-BAX(mito, G108V)

   Plasmid

   #233343

   Purpose

   Stable expression of EGFP-LOV2(N538E)-BAX(G108V)-OMP25 in mammalian cells. The G108V mutation suppresses pore-forming activity of BAX.

   Depositor

   Noboru Mizushima

   Article

   Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

   Inserts

   LOV2 domain of phototropin1
   BAX (BAX Human)
   Omp25 (Synj2bp Rat)
   

   Use

   Retroviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   N-terminus and C-terminus are deleted. BAX(3-171)…

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMRX-IP-EGFP-PA-BAX(lyso, G108V)

   Plasmid

   #233345

   Purpose

   Stable expression of EGFP-LOV2(G528A, N538E)-BAX-TMEM106B in mammalian cells. The G108V mutation suppresses pore-forming activity of BAX.

   Depositor

   Noboru Mizushima

   Article

   Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

   Inserts

   LOV2 domain of phototropin1
   BAX (BAX Human)
   TMEM106B (TMEM106B Human)
   

   Use

   Retroviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   BAX(3-171), N-terminus and C-terminus are deleted…

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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7. pMRX-IP-EGFP-PA-BAX(lyso)

   Plasmid

   #228939

   Purpose

   Stable expression of EGFP-LOV2(G528A, N538E)-BAX-TMEM106B in mammalian cells. Photoactivatable BAX localizes on lysosomal membrane and induces lysosomal rupture upon blue light stimulation.

   Depositor

   Noboru Mizushima

   Article

   Nagashima et al J Biol Chem. 2025 Mar 18;301(4):108421.

   Inserts

   LOV2 domain of phototropin1
   BAX (BAX Human)
   TMEM106B (TMEM106B Human)
   

   Use

   Retroviral

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   N-terminus and C-terminus are deleted. BAX(3-171)…

   Available Since

   April 28, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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8. pBIG1a_StrepII-Hook2_FTS_FHIP2A

   Plasmid

   #222302

   Purpose

   Co-expresses full-length human FHF (FTS, StrepII-HOOK2 and FHIP2A) in a pBIG1a vector

   Depositor

   Andrew Carter

   Article

   Abid Ali et al Nat Struct Mol Biol. 2025 Apr;32(4):756-

   Inserts

   HOOK2 (HOOK2 Human)
   FTS (AKTIP Human)
   FHIP2A (FHIP2A Human)
   

   Tags

   StrepII-Psc

   Expression

   Insect

   Available Since

   Oct. 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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9. Lenti-N1303K-ngRNA+14_EF1a-puroR

   Plasmid

   #207359

   Purpose

   Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of N1303K-CFTR via prime editing and EF1a-driven puromycin resistance gene.

   Depositor

   Marianne Carlon

   Article

   Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

   Insert

   N1303K-CFTR +14 ngRNA
   

   Use

   Lentiviral

   Available Since

   April 19, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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10. Lenti-L227R-ngRNA+15_EF1a-puroR

    Plasmid

    #207360

    Purpose

    Lentiviral transfer plasmid encoding hU6-driven expression of a ngRNA for correction of L227R-CFTR via prime editing and EF1a-driven puromycin resistance gene.

    Depositor

    Marianne Carlon

    Article

    Bulcaen et al Cell Rep Med. 2024 May 21;5(5):101544. d

    Insert

    L227R-CFTR +15 ngRNA
    

    Use

    Lentiviral

    Available Since

    April 19, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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11. pcDNA3_ATP10B-G671R-N865K

    Plasmid

    #203699

    Purpose

    expresses ATP10B with the pathogenic mutations G671R and N865K

    Depositor

    Peter Vangheluwe

    Article

    Martin et al Acta Neuropathol. 2020 Jun;139(6):1001-1

    Insert

    ATP10B (ATP10B Human)
    

    Expression

    Mammalian

    Mutation

    G671R, N865K

    Available Since

    Nov. 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pInducer 21-3xFlag-hMEFV-F479L

    Plasmid

    #195477

    Purpose

    pInducer21 plasmid containing the human MEFV gene with the F479L mutation (associated with Familial Mediterranean Fever) with a 3xFlag tag at the N-terminus

    Depositor

    Thomas Henry

    Article

    Chirita et al Cell Death Dis. 2023 Mar 25;14(3):213. d

    Insert

    MEFV (MEFV Human)
    

    Use

    Lentiviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    changed phenylalanine 479 to leucine

    Available Since

    March 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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13. pInducer 21-3xFlag-hMEFV-ΔPYD

    Plasmid

    #195478

    Purpose

    pInducer21 plasmid containing the human MEFV gene with a deletion of residues 1 - 92 (the resulting pyrin protein lacks the PYD domain) with a 3xFlag tag at the N-terminus

    Depositor

    Thomas Henry

    Article

    Chirita et al Cell Death Dis. 2023 Mar 25;14(3):213. d

    Insert

    MEFV (MEFV Human)
    

    Use

    Lentiviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    deletion of residues 1-92 of pyrin (the PYD domai…

    Available Since

    March 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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14. pInducer21-3xFlag-hMEFV-Q426R

    Plasmid

    #195475

    Purpose

    pInducer21 plasmid containing the human MEFV gene with the Q426R mutation (associated with Familial Mediterranean Fever) with a 3xFlag tag at the N-terminus

    Depositor

    Thomas Henry

    Article

    Chirita et al Cell Death Dis. 2023 Mar 25;14(3):213. d

    Insert

    MEFV (MEFV Human)
    

    Use

    Lentiviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    changed glutamine 426 to arginine

    Available Since

    March 7, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pInducer 21-3xFlag-hMEFV-S580X

    Plasmid

    #195474

    Purpose

    pInducer21 plasmid containing the human MEFV gene with the S580X mutation (stop codon leading to the truncation of the B30.2 domain of the pyrin protein) with a 3xFlag tag at the N-terminus

    Depositor

    Thomas Henry

    Article

    Chirita et al Cell Death Dis. 2023 Mar 25;14(3):213. d

    Insert

    MEFV (MEFV Human)
    

    Use

    Lentiviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    changed S580 to a stop codon

    Available Since

    March 6, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. pCS2-CIB1-mRuby-Rab35

    Plasmid

    #194334

    Purpose

    For use in light-induced Rab35 protein inactivation through the interaction with CRY2

    Depositor

    Heidi Hehnly

    Article

    Aljiboury et al PLoS Genet. 2023 May 15;19(5):e1010765.

    Inserts

    CIB1 (CIB1 Mustard Weed)
    Rab35 (RAB35 Human)
    

    Tags

    mRuby

    Expression

    Mammalian

    Promoter

    CMV IE94

    Available Since

    Jan. 17, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pCMV_SEPT9_i3 Gmut-msfGFP

    Plasmid

    #180326

    Purpose

    mammalian expression of human SEPT9_i3 Gmut fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN9_v3 (SEPTIN9 Human)
    

    Tags

    msfGFP

    Expression

    Mammalian

    Mutation

    SEPT9_i3 W502A, H512D

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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18. pnEA-vH_His-TEV-SEPT2 NCmut-msfGFP

    Plasmid

    #180311

    Purpose

    bacterial expression of human SEPT2 NCmut fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN2 (SEPTIN2 Human)
    

    Tags

    His6-TEV and msfGFP

    Expression

    Bacterial

    Mutation

    SEPT2 F20D, V27D

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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19. pCMV_msfGFP-SEPT7 Gmut1

    Plasmid

    #180316

    Purpose

    mammalian expression of human SEPT7 Gmut1 fused to monomeric superfolder GFP

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN7 (SEPTIN7 Human)
    

    Tags

    msfGFP

    Expression

    Mammalian

    Mutation

    SEPT7 W269A, H279D

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pCMV_SEPT9_i3-mApple-CAAX

    Plasmid

    #180324

    Purpose

    mammalian expression of human SEPT9_i3 fused to monomeric Apple and CAAX (HRas)

    Depositor

    Manos Mavrakis

    Article

    Martins et al J Cell Biol. 2023 Mar 6;222(3):e20220301

    Insert

    SEPTIN9_v3 (SEPTIN9 Human)
    

    Tags

    mApple

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    Dec. 1, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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