We narrowed to 80 results for: SHP2

1. SHP2(WT)@pLKO-Trex-SBP

   Plasmid

   #85457

   Purpose

   Gene expression

   Depositor

   Darrin Stuart

   Article

   Chen et al Nature. 2016 Jul 7;535(7610):148-52.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Lentiviral

   Tags

   SBP Tag

   Expression

   Mammalian

   Mutation

   Promoter

   RSV

   Available since

   Feb. 6, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pFastBac (GST-SNAP-Shp2)

   Plasmid

   #177897

   Purpose

   Baculo expression of GST tag fused to SNAP tag and human Shp2

   Depositor

   Ron Vale

   Article

   Hui et al Science. 2017 Mar 31;355(6332):1428-1433

   Insert

   Shp2 (PTPN11 Human)
   

   Use

   Tags

   TEV-GST-PreScission cut site-SNAP tag

   Expression

   Insect

   Mutation

   Promoter

   Polyhedrin

   Available since

   Dec. 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. SHP2(C459S)@pLKO-Trex-HA

   Plasmid

   #85459

   Purpose

   Expresses SHP2 mutant in mammalian cells

   Depositor

   Darrin Stuart

   Article

   Chen et al Nature. 2016 Jul 7;535(7610):148-52.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Lentiviral

   Tags

   HA

   Expression

   Mammalian

   Mutation

   C459S

   Promoter

   RSV

   Available since

   Feb. 6, 2017

   Availability

   Academic Institutions and Nonprofits only

4. RapR-Shp2-mVenus-flag

   Plasmid

   #188655

   Purpose

   Rapamycin regulated Shp2 phosphatase with mVenus and flag tag

   Depositor

   Andrei Karginov

   Article

   Fauser et al J Cell Biol. 2022 Aug 1;221(8). pii: 213

   Insert

   Shp2
   

   Use

   Tags

   Flag and mVenus

   Expression

   Mammalian

   Mutation

   iFKBP insertion at V406 with deletion of residues…

   Promoter

   CMV

   Available since

   Aug. 19, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pBABE-puro SHP2 D61A

   Plasmid

   #8330

   Depositor

   Ben Neel

   Article

   Zhang et al Mol Cell Biol 2002 Jun;22(12):4062-72.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Retroviral

   Tags

   Expression

   Mammalian

   Mutation

   D61A (activated mutant)

   Promoter

   Available since

   June 23, 2005

   Availability

   Academic Institutions and Nonprofits only

6. pGEX-4T2 SHP2 E76A

   Plasmid

   #8324

   Depositor

   Ben Neel

   Article

   O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   E76A (activated mutant)

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

7. pGEX-4T2 SHP2 D61A

   Plasmid

   #8323

   Depositor

   Ben Neel

   Article

   O'Reilly et al Mol Cell Biol 2000 Jan;20(1):299-311.

   Insert

   SHP2 (PTPN11 Human)
   

   Use

   Tags

   GST

   Expression

   Bacterial

   Mutation

   D61A (activated mutant)

   Promoter

   Available since

   June 17, 2005

   Availability

   Academic Institutions and Nonprofits only

8. pGEX6P2(GST-SNAP-Shp2tSH2)

   Plasmid

   #177907

   Purpose

   Baculo expression of GST tag fused to SNAPtag and human Shp2 tandem SH2 domains

   Depositor

   Ron Vale

   Article

   Hui et al Science. 2017 Mar 31;355(6332):1428-1433

   Insert

   Shp2 tandem SH2 domains (aa 6-218 only) (PTPN11 Human)
   

   Use

   Tags

   GST-PreScission cut site-SNAP tag

   Expression

   Bacterial

   Mutation

   Promoter

   tac

   Available since

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pMIG II SIN-SV40-mCherry-SHP2

   Plasmid

   #180800

   Purpose

   Expression of mouse SHP2 fused to N-terminal mCherry

   Depositor

   Enfu Hui

   Article

   Xu et al J Cell Biol. 2020 Jun 1;219(6). pii: 151

   Insert

   SHP2 (Ptpn11 Mouse)
   

   Use

   Retroviral

   Tags

   Expression

   Mutation

   Promoter

   SV40

   Available since

   March 15, 2022

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pGEX-4T-1-Shp2 T7DA/S189D SH2s

    Plasmid

    #67577

    Purpose

    Expresses GST-tagged Shp2 T73D/S189D SH2 domains in bacteria

    Depositor

    Graeme Carnegie

    Article

    Burmeister et al J Biol Chem. 2015 May 8;290(19):12058-67

    Insert

    Src homology 2 domain-containing phosphatase 2
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Deleted amino acid residues 219-597, changed T73 …

    Promoter

    Available since

    Sept. 14, 2015

    Availability

    Academic Institutions and Nonprofits only

11. SHP2(T253M/Q257L)@pLKO-Trex-SBP

    Plasmid

    #85458

    Purpose

    SHP2 mutant gene expression

    Depositor

    Darrin Stuart

    Article

    Chen et al Nature. 2016 Jul 7;535(7610):148-52.

    Insert

    SHP2 (PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    SBP Tag

    Expression

    Mammalian

    Mutation

    T253M/Q257L

    Promoter

    RSV

    Available since

    Feb. 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pHR-SV40-mCherry-SHP1 (SHP2-cSH2)

    Plasmid

    #180822

    Purpose

    Expression of N-terminal mCherry tagged human SHP1 with its cSH2 replaced by SHP2-cSH2

    Depositor

    Enfu Hui

    Article

    Xu et al Elife. 2021 Nov 4;10. pii: 74276. doi: 1

    Insert

    SHP1 (SHP2-cSH2) (PTPN6, PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    SV40

    Available since

    March 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pHR-SV40-mCherry-SHP1 (SHP2-nSH2, cSH2)

    Plasmid

    #180823

    Purpose

    Expression of N-terminal mCherry tagged human SHP1 with its nSH2 and cSH2 replaced by nSH2 and cSH2 of SHP2

    Depositor

    Enfu Hui

    Article

    Xu et al Elife. 2021 Nov 4;10. pii: 74276. doi: 1

    Insert

    SHP1 (SHP2-nSH2, cSH2) (PTPN6, PTPN11 Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    SV40

    Available since

    March 14, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pGEX SHP-2(N)-SH2

    Plasmid

    #46498

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(N) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 1-104

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pGEX SHP-2(NC)-SH2

    Plasmid

    #46499

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(NC) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 1-222

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pGEX SHP-2(C)-SH2

    Plasmid

    #46497

    Depositor

    Bruce Mayer

    Article

    Machida et al Mol Cell. 2007 Jun 22;26(6):899-915.

    Insert

    SHP-2(C) (PTPN11 Human)
    

    Use

    Tags

    GST and PreScission

    Expression

    Bacterial

    Mutation

    contains amino acids 101-222

    Promoter

    Tac

    Available since

    July 10, 2013

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pENTR2b-PTPN11

    Plasmid

    #215476

    Purpose

    Gateway entry vector with Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Gateway entry vector

    Tags

    Expression

    Mutation

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

18. pENTR2b-PTPN11-Clover

    Plasmid

    #215519

    Purpose

    Gateway entry vector with clover-tagged Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Gateway entry vector

    Tags

    Clover

    Expression

    Mutation

    Promoter

    none

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

19. pEF.DEST51-PTPN11

    Plasmid

    #215523

    Purpose

    Expression vector with Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge

20. pEF.DEST51-PTPN11-Clover

    Plasmid

    #215525

    Purpose

    Expression vector with clover-tagged Shp2

    Depositor

    Johanna Ivaska

    Article

    Conway et al Nat Cell Biol. 2025 May 26. doi: 10.1038

    Insert

    PTPN11 (PTPN11 Human)
    

    Use

    Tags

    Clover

    Expression

    Mammalian

    Mutation

    Promoter

    EF1a

    Available since

    May 29, 2025

    Availability

    Industry, Academic Institutions, and Nonprofits

    

    Enlarge