We narrowed to 250 results for: SYN1

1. pAAV-Syn1-tTA

   Plasmid

   #104109

   Purpose

   AAV-mediated expression of tTA under the Syn1 promoter.

   Depositor

   Takeshi Imai

   Article

   Sakaguchi et al eLife. 2018 Nov 20;7. pii: 40350. doi: 1

   Insert

   tTA2
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn1

   Available Since

   June 22, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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2. pAAV-ihSyn1-tTA

   Plasmid

   #99120

   Purpose

   An AAV genome that expresses tTA from the hSyn1 promoter that contains a positive feedback loop for amplifed expression of the tTA

   Depositor

   Viviana Gradinaru

   Article

   Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

   Has Service

   AAV1

   Insert

   tTA
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   *(see below)

   Promoter

   ihSyn1

   Available Since

   Aug. 15, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pAAV-hSyn1-tTA

   Plasmid

   #99119

   Purpose

   An AAV genome that expresses tTA from the hSyn1 promoter

   Depositor

   Viviana Gradinaru

   Article

   Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

   Insert

   tTA
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   *(see below)

   Promoter

   hSyn1

   Available Since

   Sept. 15, 2017

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pAAV-hSyn1-mRuby2

   Plasmid

   #99126

   Purpose

   An AAV genome that expresses the fluorescent protein mRuby2 from the hSyn1 promoter

   Depositor

   Viviana Gradinaru

   Article

   Chan et al Nat Neurosci. 2017 Aug;20(8):1172-1179.

   Insert

   mRuby2
   

   Use

   AAV

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hSyn1

   Available Since

   Aug. 16, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. pAAV-hSyn1-tdTomatof

   Plasmid

   #104060

   Purpose

   Also known as hSyn1-tdTomato-f. AAV expression of Farnylsated tdtomato for tracing

   Depositor

   Viviana Gradinaru

   Article

   Challis et al Nat Protoc. 2019 Feb;14(2):379-414. doi:

   Insert

   tdTomato
   

   Use

   AAV

   Tags

   Expression

   Mutation

   Promoter

   hSyn

   Available Since

   April 18, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMH4-Syn1-Ratio1XsypHy

   Plasmid

   #44268

   Depositor

   Tobias Rose, Thomas Oertner

   Article

   Rose et al Neuron. 2013 Mar 20;77(6):1109-21. doi:

   Insert

   SypHy1x-tdimer2(12)
   

   Use

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Aug. 2, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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7. pMH4-Syn1-Ratio2XsypHy

   Plasmid

   #44269

   Depositor

   Tobias Rose, Thomas Oertner

   Article

   Rose et al Neuron. 2013 Mar 20;77(6):1109-21. doi:

   Insert

   SypHy2x-tdimer2(12)
   

   Use

   Tags

   Expression

   Mutation

   Promoter

   Available Since

   Aug. 2, 2013

   Availability

   Academic Institutions and Nonprofits only

   

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8. pX330_rSyn1 sgRNA / hSpCas9

   Plasmid

   #172840

   Purpose

   Mammalian expression of a sgRNA targeting the intron 21 (last intron) of rSyn1 (Zhong et al, eLife 2021) under the U6 promotor and hSpCas9 under the CAG promotor. This construct is based on pX330.

   Depositor

   Haining Zhong

   Article

   Zhong et al Elife. 2021 Jun 8;10. pii: 64911. doi: 1

   Insert

   sgRNA targeting intron 21 of rSyn1 under the U6 promotor and hSpCas9 under the CAG promotor
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   Aug. 24, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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9. [#GS16-LV] Syn1-MitoTRACER - Donor

   Plasmid

   #233565

   Purpose

   Lentiviral construct of the MitoTRACER genetic reporter to be expressed in the donor cells under the Synapsin1 promotor

   Depositor

   Simon Grelet

   Article

   Hoover et al Nature. 2025 Jun 25. doi: 10.1038/s41586

   Insert

   MitoTRACER-Donor
   

   Use

   Lentiviral and Synthetic Biology

   Tags

   GFP11 and HA Tag

   Expression

   Mammalian

   Mutation

   Promoter

   Available Since

   June 5, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pAM-AAV-hSyn1-EGFP

    Plasmid

    #153205

    Purpose

    Human synapsin-1 (hSyn1) promoter-mediates gene expression in retinal neurons with fluorescent reporter

    Depositor

    Yang Hu

    Article

    Wang et al J Neurosci. 2020 Apr 9. pii: JNEUROSCI.0

    Type

    Empty backbone

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    July 10, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. [#GS24 -LV] Syn1-GFP-OMP25

    Plasmid

    #233566

    Purpose

    Lentiviral construct of mitochondrial localized GFP to be expressed in the donor cells under the Synapsin1 promotor

    Depositor

    Simon Grelet

    Article

    Hoover et al Nature. 2025 Jun 25. doi: 10.1038/s41586

    Insert

    eGFP (eGFP Synthetic, Aequorea victoria)
    

    Use

    Lentiviral and Synthetic Biology

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available Since

    June 5, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. AAV phSyn1(S)-tdTomato-WPRE

    Plasmid

    #51506

    Purpose

    Can be used to generate AAV virus that will express tdTomato in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Oh et al Nature. 2014 Apr 10;508(7495):207-14. do

    Has Service

    AAV5

    Insert

    tdTomato
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    phSyn1

    Available Since

    Sept. 3, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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13. AAV pmSyn1-EBFP-Cre

    Plasmid

    #51507

    Purpose

    Can be used to generate AAV virus that will express Cre in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Has Service

    AAV5

    Insert

    EBFP-Cre
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    pmSyn1

    Available Since

    July 14, 2014

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. AAVS1 SA-2A-puro-pA_hSYN1_dTomato-SV40pA

    Plasmid

    #196192

    Purpose

    human synapsin promoter driven dTomato expression at human AAVS1 safe harbour locus

    Depositor

    Jürgen Knoblich

    Article

    Sidhaye et al Elife. 2023 Mar 29;12:e85135. doi: 10.75

    Insert

    2xCHS4_hSYN1_INTRON_dTomato-WPRE-SV40-2xCHS4
    

    Use

    Znf donor

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    March 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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15. pAAV-hSYN1-fDIO-rtTA

    Plasmid

    #166598

    Purpose

    Encodes Flp-dependent rtTA

    Depositor

    Martin Myers

    Article

    Sabatini et al eLife. 2021 Mar 11;10. pii: 66835. doi:

    Insert

    rtTA
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    human synapsin 1

    Available Since

    April 5, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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16. pAAV_hSyn1-SIO-stGtACR2-FusionRed

    Plasmid

    #105677

    Purpose

    Expresses a soma-targeted GtACR2 in Cre-expressing neurons

    Depositor

    Ofer Yizhar

    Article

    Mahn et al Nat Commun. 2018 Oct 8;9(1):4125. doi: 1

    Has Service

    AAV Retrograde, AAV1, and AAV5

    Insert

    stGtACR2
    

    Use

    AAV

    Tags

    FusionRed and Kv2.1

    Expression

    Mammalian

    Mutation

    Promoter

    hSyn1

    Available Since

    Feb. 23, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. AAV phSyn1(S)-DreO-bGHpA

    Plasmid

    #50363

    Purpose

    Can be used to generate AAV virus that will express DreO recombinase in neurons from the synapsin promoter

    Depositor

    Hongkui Zeng

    Article

    Madisen et al Neuron. 2015 Mar 4;85(5):942-58. doi: 10

    Has Service

    AAV Retrograde and AAV5

    Insert

    DreO recombinase
    

    Use

    AAV

    Tags

    none

    Expression

    Mutation

    Sequence optimized for expression in mammalian ce…

    Promoter

    hSyn1

    Available Since

    Jan. 16, 2014

    Availability

    Academic Institutions and Nonprofits only

    

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18. pAAV-hSyn1-TVAmCherry-2A-G(N2c)

    Plasmid

    #194354

    Purpose

    AAV expressing TVA-mCherry fusion and Rabies Glycoprotein (G) of CVS-N2c strain under neuronal-specific promoter

    Depositor

    Marco Tripodi

    Article

    Lee et al Nat Methods. 2023 Apr;20(4):580-589. doi

    Inserts

    TVA-mCherry fusion protein
    Rabies CVS-N2c Glycoprotein
    

    Use

    AAV

    Tags

    Expression

    Mutation

    Promoter

    Available Since

    Aug. 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. pOTTC1484 - pAAV SYN1 HA-hM4D(Gi)

    Plasmid

    #121538

    Purpose

    An adeno-associated viral vector expressing HA-tagged inhibitory DREADD (hM4D(Gi)) from a synapsin promoter

    Depositor

    Christopher Richie

    Article

    Galvan et al Eur J Neurosci. 2019 May 7. doi: 10.1111

    Has Service

    AAV2 and AAV5

    Insert

    HA-tagged hM4D(Gi) (CHRM4 Human)
    

    Use

    AAV

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    SYN1

    Available Since

    Feb. 21, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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20. pLenti-hSyn1-eNpHR3.0-iRFP713

    Plasmid

    #197594

    Purpose

    Lentiviral transfer vector for the neuronal expression of eNpHR3.0-iRFP713 (halorhodopsin for the inhibition of neuronal activity)

    Depositor

    Patrik Verstreken

    Insert

    eNpHR3.0-iRFP713
    

    Use

    Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    hSynI

    Available Since

    March 30, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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