We narrowed to 461 results for: LEP

1. hKCNB1 F416L

   Plasmid

   #124491

   Purpose

   missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

   Depositor

   Federico Sesti

   Article

   Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

   Insert

   human KCNB1 (KCNB1 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   changed phenyalanine 416 to leucine

   Available Since

   Sept. 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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2. pC013 - Twinstrep-SUMO-huLwCas13a

   Plasmid

   #90097

   Purpose

   Twinstrep-SUMO-huLwCas13a for recombinant protein bacterial expression. Insert is human codon optimized but expresses well in bacteria.

   Depositor

   Feng Zhang

   Article

   Gootenberg et al Science. 2017 Apr 13. pii: eaam9321. doi

   Insert

   LwCas13a
   

   Use

   CRISPR

   Tags

   6xHis-Twin Strep-SUMO

   Expression

   Bacterial

   Available Since

   June 13, 2017

   Availability

   Industry, Academic Institutions, and Nonprofits

   

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3. pcDNA5FRT_KCNQ3

   Plasmid

   #173163

   Purpose

   To generate Flp-In CHO-KCNQ3 stable cells

   Depositor

   Al George

   Article

   Vanoye et al JCI Insight. 2022 Mar 8;7(5):e156314. do

   Insert

   KCNQ3 (KCNQ3 Human)
   

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   Sept. 16, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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4. Cx32R220stop

   Plasmid

   #78151

   Purpose

   Mammalian Expression of the first 219 amino acids of Connexin 32 and EGFP from a bicistronic mRNA

   Depositor

   Mario Bortolozzi

   Article

   Carrer et al Hum Mol Genet. 2017 Oct 25. pii: 4565496

   Insert

   Connexin 32 (GJB1 Human)
   

   Tags

   EGFP

   Expression

   Mammalian

   Mutation

   Only contains first 219 residues

   Promoter

   CMV

   Available Since

   Dec. 4, 2017

   Availability

   Academic Institutions and Nonprofits only

5. pAAV.E2.ChETA

   Plasmid

   #220310

   Purpose

   Directs ChETA optogenetic actuator to fast spiking interneurons in cortex. Allows for single APs to be evoked.

   Depositor

   Matt Rowan

   Article

   Kumar et al Nat Commun. 2024 Apr 1;15(1):2823. doi:

   Insert

   ChETA
   

   Use

   AAV

   Expression

   Mammalian

   Promoter

   S5E2

   Available Since

   June 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. MSCV-TAP(FLAG-HA) CYLD

   Plasmid

   #60031

   Purpose

   CYLD with N-terminal TAP-tag (HA,FLAG) and IRES-Puro to allow tagged protein to be maintained

   Depositor

   Stephen Elledge

   Article

   Stegmeier et al Proc Natl Acad Sci U S A. 2007 May 22. 1

   Insert

   Cylindromatosis (CYLD Human)
   

   Use

   Retroviral

   Tags

   FLAG, HA, and IRES Puro

   Expression

   Mammalian

   Promoter

   LTR-driven expression

   Available Since

   Feb. 24, 2016

   Availability

   Academic Institutions and Nonprofits only

7. pRC/RSV-rat Agt

   Plasmid

   #122104

   Purpose

   Expression of angiotensinogen

   Depositor

   John Chan

   Article

   Zhang et al J Am Soc Nephrol. 2002 Feb;13(2):302-12.

   Insert

   angiotensinogen (Agt Rat)
   

   Expression

   Mammalian

   Promoter

   RSV promoter

   Available Since

   July 15, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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8. PC1575

   Plasmid

   #232088

   Purpose

   Mammalian expression plasmid for ubiquibody (uAb) cloning backbone. Includes an Esp3I restriction site directly upstream of GSGSG linker and CHIPΔTPR CDS and a C-terminal IRES-mCherry cassette.

   Depositor

   Pranam Chatterjee

   Article

   Bhat et al Sci Adv. 2025 Jan 24;11(4):eadr8638. doi

   Insert

   uAb with cloning Esp3I restriction site
   

   Tags

   IRES-mCherry

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   April 24, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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9. hKCNB1 R312H

   Plasmid

   #124488

   Purpose

   missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

   Depositor

   Federico Sesti

   Article

   Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

   Insert

   human KCNB1 (KCNB1 Human)
   

   Tags

   HA

   Expression

   Mammalian

   Mutation

   changed arginine 312 to histidine

   Available Since

   Sept. 3, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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10. hKCNB1 G379R

    Plasmid

    #124489

    Purpose

    missense mutation in children with EOEE. HA tagged in C-terminus, pCIneo vector

    Depositor

    Federico Sesti

    Article

    Yu et al FASEB J. 2019 Dec;33(12):14680-14689. do

    Insert

    human KCNB1 (KCNB1 Human)
    

    Tags

    HA

    Expression

    Mammalian

    Mutation

    changed glycine at 379 to arginine

    Available Since

    April 16, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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11. p3E ubb polyA

    Plasmid

    #195977

    Purpose

    Gateway p3E vector

    Depositor

    Alexa Burger, Christian Mosimann

    Article

    Kemmler et al Development. 2023 Mar 28:dev.201531. doi

    Insert

    ubb:polyA (ubb Zebrafish)
    

    Use

    Other

    Available Since

    Feb. 24, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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12. pKLV-EF1aGFP2AKAT7-W

    Plasmid

    #159292

    Purpose

    Lentiviral vector expressing GFP and KAT7 (gRNA-resistant) driven by human EF1a promoter

    Depositor

    Kosuke Yusa

    Article

    Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

    Insert

    KAT7 (KAT7 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Mutation

    CRISPR sites mutated (gRNA ID. 5 and A10)

    Promoter

    human EF1a promoter

    Available Since

    Dec. 3, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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13. pAGT9569

    Plasmid

    #219431

    Purpose

    Transcriptional unit (MoClo-position 2): pAtRPS5a_PapE-4LF2-N-SpCas9i-N_tNOS

    Depositor

    Tom Schreiber

    Article

    Schreiber et al Mol Plant. 2024 Mar 22:S1674-2052(24)000

    Insert

    LB_AtRPS5a:PapE-4xLF2-NLS-SpCas9i-NLS:tNOS_RB (Position 2)
    

    Use

    CRISPR and Synthetic Biology; Moclo compatible le…

    Tags

    PapE-4LF2

    Expression

    Plant

    Available Since

    July 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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14. pKLV2-U6gRNA5(gKAT7-5)-PGKpuro2ABFP-W

    Plasmid

    #159287

    Purpose

    Lentiviral vector expressing gRNA targeting KAT7 (gRNA ID. 5)

    Depositor

    Kosuke Yusa

    Article

    Au et al Leukemia. 2021 Apr;35(4):1012-1022. doi:

    Insert

    guide RNA targeting KAT7 (ID. 5) (KAT7 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    human U6 promoter

    Available Since

    Sept. 23, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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15. hKCNQ5(WT).ires.GFP-pcDNA3

    Plasmid

    #204360

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ5 (KCNQ5 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. hKCNQ3(WT).ires.mCherry-pcDNA3

    Plasmid

    #204362

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ3 (KCNQ3 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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17. pAGT9054

    Plasmid

    #219430

    Purpose

    Transcriptional unit (MoClo-position 2): 2x35Ss_Omega enhancer_PapE-4LF2-N-SpCas9i-N_tOCS

    Depositor

    Tom Schreiber

    Article

    Schreiber et al Mol Plant. 2024 Mar 22:S1674-2052(24)000

    Insert

    LB_2x35Ss-omega enhancer:PapE-4xLF2-NLS-SpCas9i-NLS:tOCS_RB (Position 2)
    

    Use

    CRISPR; Moclo compatible level 1 module (position…

    Tags

    PapE-4LF2

    Expression

    Plant

    Available Since

    July 31, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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18. hBACE1(D289N).ires.mCherry-pcDNA3

    Plasmid

    #204363

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    BACE1 (BACE1 Human)
    

    Expression

    Mammalian

    Mutation

    D289N

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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19. hKCNQ5(WT).ires.mScarlet-pcDNA3

    Plasmid

    #204361

    Purpose

    Heterologous expression in mammalian cell lines or Xenopus oocyte (T7 RNA pol)

    Depositor

    Aguan Wei

    Article

    Wei et al J Neurophysiol. 2022 Jul 1;128(1):40-61.

    Insert

    KCNQ5 (KCNQ5 Human)
    

    Expression

    Mammalian

    Promoter

    CMV/T7 RNApol

    Available Since

    Aug. 21, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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20. Cherry-HA-KCC2

    Plasmid

    #104077

    Purpose

    To visualize the expression and localization of potassium-chloride cotransporter type 2 (KCC2)

    Depositor

    Igor Medyna

    Article

    Kahle et al EMBO Rep. 2014 Jul;15(7):766-74. doi: 10

    Insert

    KCC2 (b isoform) (Slc12a5 Rat)
    

    Tags

    mCherry-HA tag

    Expression

    Mammalian

    Mutation

    EcoR1 site in rat KCC2 was removed by silent muta…

    Promoter

    UbC

    Available Since

    Feb. 20, 2018

    Availability

    Academic Institutions and Nonprofits only

    

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