We narrowed to 7,223 results for: ALP

1. W118-1_hRSK3(RPS6KA2)_K91A_K444A

   Plasmid

   #180385

   Purpose

   lentiviral transduction of human RSK3 (RPS6KA2) gene with point mutations (K91A and K444A) that inactivate kinase activity

   Depositor

   Huda Zoghbi

   Article

   Lee et al EMBO J. 2021 Apr 1;40(7):e106106. doi: 1

   Insert

   RPS6KA2_K91A/K444A (RPS6KA2 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   K91A/K444A

   Promoter

   CMV

   Available since

   Feb. 9, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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2. pSN33

   Plasmid

   #100118

   Purpose

   expresses a chimeric KLF4-repressor fusion

   Depositor

   Mark Ptashne

   Article

   Narayan et al Cell Rep. 2017 Aug 15;20(7):1585-1596. d

   Insert

   mCherry-P2A-KLF4 fused to full length HP1 alpha (KLF4, CBX5 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Sept. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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3. TET1CD-CRY2-EGFP

   Plasmid

   #82555

   Purpose

   Encodes TET1 under LITE2.0 system

   Depositor

   Joseph Irudayaraj

   Article

   Lo et al Sci Rep. 2017 Feb 9;7:42047. doi: 10.103

   Inserts

   TET1 (TET1 Human)
   CRY2 (CRY2 Mustard Weed)
   EGFP
   

   Use

   AAV

   Tags

   2A, NLS(alpha-imp), and NLS-VP64

   Expression

   Mammalian

   Mutation

   CRY2PHR (N-terminal photolyase homology region do…

   Promoter

   EF-1alpha

   Available since

   Sept. 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. pDONR223_PRKCA_WT

   Plasmid

   #82225

   Purpose

   Gateway Donor vector containing PRKCA , part of the Target Accelerator Plasmid Collection.

   Depositor

   David Root, William Hahn, Jesse Boehm

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   PRKCA (PRKCA Human)
   

   Use

   Gateway entry vector

   Tags

   Expression

   Mutation

   WT

   Promoter

   None

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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5. CAMK2A gRNA (BRDN0001162256)

   Plasmid

   #76929

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human CAMK2A

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   CAMK2A (CAMK2A Human)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   hU6

   Available since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. pDONR223_PIK3R1_WT

   Plasmid

   #81748

   Purpose

   Gateway Donor vector containing PIK3R1 , part of the Target Accelerator Plasmid Collection.

   Depositor

   David Root, William Hahn, Jesse Boehm

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   PIK3R1 (PIK3R1 Human)
   

   Use

   Gateway entry vector

   Tags

   Expression

   Mutation

   E181K

   Promoter

   None

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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7. pDONR223_PPP2R1A_p.R258H

   Plasmid

   #81581

   Purpose

   Gateway Donor vector containing PPP2R1A , part of the Target Accelerator Plasmid Collection.

   Depositor

   David Root, William Hahn, Jesse Boehm

   Article

   Kim et al Cancer Discov. 2016 Jul;6(7):714-26. doi

   Insert

   PPP2R1A (PPP2R1A Human)
   

   Use

   Gateway entry vector

   Tags

   Expression

   Mutation

   R258H; p.588_589delLA-insRL

   Promoter

   None

   Available since

   April 24, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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8. pHAGE-PIK3R1-E160*

   Plasmid

   #116586

   Purpose

   Lentiviral expression of PIK3R1 E160*

   Depositor

   Gordon Mills, Kenneth Scott

   Article

   Ng et al Cancer Cell. 2018 Mar 12;33(3):450-462.e

   Insert

   PIK3R1 (PIK3R1 Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mutation

   E160*

   Promoter

   Available since

   March 14, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. GP1BB

   Plasmid

   #51908

   Purpose

   Expresses full-length Platelet glycoprotein Ib beta chain precursor ectodomain in mammalian cells. Stop codon before C-terminal rat Cd4d3+4 tag, biotinylation sequence and His tag.

   Depositor

   Gavin Wright

   Article

   Sun et al Mol Cell Proteomics. 2015 Feb 23. pii: m

   Insert

   GP1BB (GP1BB Human)
   

   Use

   Tags

   His tag, enzymatic biotinylation sequence, and ra…

   Expression

   Mammalian

   Mutation

   Stop Codon at amino acid 149, before CD4, bio and…

   Promoter

   CMV

   Available since

   Feb. 27, 2015

   Availability

   Academic Institutions and Nonprofits only

   

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10. PAK1 gRNA (BRDN0001145958)

    Plasmid

    #76464

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human PAK1

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    PAK1 (PAK1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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11. CAMK2A gRNA (BRDN0001149531)

    Plasmid

    #76928

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human CAMK2A

    Depositor

    David Root, John Doench

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    CAMK2A (CAMK2A Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pOET3-6xHis-hSMSr-ΔSAMD

    Plasmid

    #236225

    Purpose

    Express N-terminal His-tagged human SMSr (SAMD8)-sterile alpha motif domain deletion mutant protein in insect cells

    Depositor

    Chiaki Murakami

    Article

    Murakami et al J Biol Chem. 2021 Jan-Jun;296:100454. do

    Insert

    SAMD8 (SAMD8 Human)
    

    Use

    Tags

    Hexa histidine tag (6xHis-tag) and enterokinase s…

    Expression

    Insect

    Mutation

    sterile alpha motif domain at N-terminal (1-231 b…

    Promoter

    Available since

    May 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. pCMV-HA_N-human Bcl6

    Plasmid

    #137851

    Purpose

    Express Bcl6 in mammalian cells

    Depositor

    Bruce Beutler

    Article

    Misawa et al Sci Immunol. 2020 Jan 24;5(43):eaaz0085.

    Insert

    B cell lymphoma 6 (BCL6 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    April 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. pCMV-HA_N-human Prkd2 without kinase domain

    Plasmid

    #138411

    Purpose

    Express Prkd2 without kinase domain in mammalian cells

    Depositor

    Bruce Beutler

    Article

    Misawa et al Sci Immunol. 2020 Jan 24;5(43):eaaz0085.

    Insert

    Prkd2 without kinase domain (PRKD2 Human)
    

    Use

    Tags

    HA

    Expression

    Mammalian

    Mutation

    kinase domain deleted from human Prkd2

    Promoter

    CMV

    Available since

    April 3, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. AAV-U6/TO-shEsr1-CMV-TetR-eGFP

    Plasmid

    #233298

    Purpose

    DOX-inducible U6 driven shRNA against mouse Esr1

    Depositor

    Dayu Lin

    Article

    Golden et al bioRxiv [Preprint]. 2024 Sep 25:2023.12.

    Insert

    Esr1 shRNA (Esr1 Mouse)
    

    Use

    AAV

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    March 24, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLenti-multi-CRISPR-sgRipk3_#2-puro

    Plasmid

    #231982

    Purpose

    Knockout mouse Ripk3

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pLenti-multi-CRISPR-sgRipk3_#1-puro

    Plasmid

    #231981

    Purpose

    Knockout mouse Ripk3

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Ripk3 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLenti-multi-CRISPR-sgMlkl_#2-puro

    Plasmid

    #231980

    Purpose

    Knockout mouse Mlkl

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLenti-multi-CRISPR-sgMlkl_#1-puro

    Plasmid

    #231979

    Purpose

    Knockout mouse Mlkl

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Mlkl Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pLenti-multi-CRISPR-sgCasp8_#2-puro

    Plasmid

    #231978

    Purpose

    Knockout mouse Casp8

    Depositor

    Brian Ruffell

    Article

    Hanggi et al Cancer Cell. 2024 Nov 13:S1535-6108(24)0

    Insert

    sgRNA with Cas9 with puromycin resistance (Casp8 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Feb. 7, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge