We narrowed to 5,111 results for: codon optimized

1. hA3A*-IscBn

   Plasmid

   #227146

   Purpose

   Vector encoding human codon-optimized nOgeuIscB fusion with two copies of UGI and hA3A* variant driven by CMV promoter

   Depositor

   Dali Li

   Article

   Xue et al Mol Cell. 2024 Aug 22;84(16):3128-3140.e

   Insert

   bpNLS-hA3A*-linker-nOgeuIscB-nucleoplasmin NLS-2XUGI-bpNLS
   

   Mutation

   D96R/E84R/V159R/H339A

   Promoter

   CMV

   Available Since

   Nov. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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2. TadA-8e-eIscBn-N-HMG-D

   Plasmid

   #227143

   Purpose

   Vector encoding human codon-optimized enhanced-activity nOgeuIscB fusion with TadA8e and HMG-D domain in N terminus driven by CMV promoter

   Depositor

   Dali Li

   Article

   Xue et al Mol Cell. 2024 Aug 22;84(16):3128-3140.e

   Insert

   bpNLS-HMG-D-linker-TadA-8e-linker-nOgeuIscB-v3-bpNLS
   

   Mutation

   D96R/E84R/V159R/H339A

   Promoter

   CMV

   Available Since

   Nov. 21, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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3. PD2529 human beta1 ecto

   Plasmid

   #221398

   Purpose

   Mammalian expression of human integrin beta1 ectodomain

   Depositor

   Timothy Springer

   Article

   Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

   Insert

   integrin beta1 ectodomain (ITGB1 Human)
   

   Tags

   AVI tag, HRV3C cleavage site, basic coil, HA tag,…

   Expression

   Mammalian

   Mutation

   codon optimized for human mature _1 residues Q1 t…

   Available Since

   Sept. 9, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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4. PD2529 human alpha5 ecto

   Plasmid

   #221394

   Purpose

   Mammalian expression of human integrin alpha5 ectodomain

   Depositor

   Timothy Springer

   Article

   Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

   Insert

   integrin alpha5 ectodomain (ITGA5 Human)
   

   Tags

   CD33 secretion peptide (MPLLLLLPLLWAGALA) and HR…

   Expression

   Mammalian

   Mutation

   codon optimized for human mature residues _5 F1 t…

   Available Since

   July 24, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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5. pDONR221-eGFP_myr

   Plasmid

   #221412

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   eGFP_myr
   

   Expression

   Mammalian

   Available Since

   July 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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6. pDONR221-eGFP

   Plasmid

   #221413

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   eGFP
   

   Expression

   Mammalian

   Available Since

   July 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pENTR-TMEM144

   Plasmid

   #221426

   Purpose

   Gateway entry clone with codon-optimized ORF sequence for subcloning into custom expression vectors

   Depositor

   RESOLUTE Consortium, Giulio Superti-Furga

   Article

   Superti-Furga et al Nat Rev Drug Discov. 2020 Jul;19(7):429-

   Insert

   TMEM144 (TMEM144 Human)
   

   Expression

   Mammalian

   Available Since

   July 18, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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8. Beta1 Q280* full-length

   Plasmid

   #221402

   Purpose

   Mammalian expression of human integrin beta1 Q280* full-length

   Depositor

   Timothy Springer

   Article

   Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

   Insert

   integrin beta1 Q280* full-length (ITGB1 Human)
   

   Tags

   CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

   Expression

   Mammalian

   Mutation

   codon-optimized mature sequence

   Available Since

   July 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. Beta1 K418* full-length

   Plasmid

   #221403

   Purpose

   Mammalian expression of human integrin beta1 K418* full-length

   Depositor

   Timothy Springer

   Article

   Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

   Insert

   integrin beta1 K418* full-length (ITGB1 Human)
   

   Tags

   CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

   Expression

   Mammalian

   Mutation

   codon-optimized mature sequence

   Available Since

   July 17, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. Beta1 N391* full-length

    Plasmid

    #221404

    Purpose

    Mammalian expression of human integrin beta1 N391* full-length

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 N391* full-length (ITGB1 Human)
    

    Tags

    CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

    Expression

    Mammalian

    Mutation

    codon-optimized mature sequence

    Available Since

    July 17, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. Beta1 Q280* K418* full-length

    Plasmid

    #221406

    Purpose

    Mammalian expression of human integrin beta1 Q280* K418* full-length

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 Q280* K418* full-length (ITGB1 Human)
    

    Tags

    CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

    Expression

    Mammalian

    Mutation

    codon-optimized mature sequence

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. Beta1 Q280* K418* ectodomain

    Plasmid

    #221399

    Purpose

    Mammalian expression of human integrin beta1 Q280* K418* ectodomain

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 Q280* K418* ectodomain (ITGB1 Human)
    

    Tags

    AVI tag, HRV3C cleavage site, basic coil, HA tag,…

    Expression

    Mammalian

    Mutation

    codon optimized for human mature _1 residues Q1 t…

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. Beta1 N562* full-length

    Plasmid

    #221405

    Purpose

    Mammalian expression of human integrin beta1 N562* full-length

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 N562* full-length (ITGB1 Human)
    

    Tags

    CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

    Expression

    Mammalian

    Mutation

    codon-optimized mature sequence

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. Beta1 N391* N562* full-length

    Plasmid

    #221407

    Purpose

    Mammalian expression of human integrin beta1 N391* N562* full-length

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 N391* N562* full-length (ITGB1 Human)
    

    Tags

    CD33 secretion peptide (MPLLLLLPLLWAGALA) and HA …

    Expression

    Mammalian

    Mutation

    codon-optimized mature sequence

    Available Since

    July 15, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pMXs-IRES-blast 3xFlag-SPNS1(R76A)

    Plasmid

    #198570

    Purpose

    SPNS1(R76A) codon-optimized orf with n-terminal 3xFlag in pMXs-IRES-Blast vector

    Depositor

    Monther Abu-Remaileh

    Article

    Scharenberg et al Sci Adv. 2023 Apr 21;9(16):eadf8966. doi

    Insert

    SPNS1(R76A) with n-terminal 3xFlag (SPNS1 Human)
    

    Use

    Retroviral

    Tags

    3xFlag

    Expression

    Mammalian

    Mutation

    changed arginine R76 to alanine (R76A)

    Available Since

    July 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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16. pMXs-IRES-blast GFP-SPNS1(E164K)

    Plasmid

    #198572

    Purpose

    SPNS1(E164K) codon-optimized orf with n-terminal 3xFlag GFP in pMXs-IRES-Blast vector

    Depositor

    Monther Abu-Remaileh

    Article

    Scharenberg et al Sci Adv. 2023 Apr 21;9(16):eadf8966. doi

    Insert

    SPNS1(E164K) with n-terminal 3xFlag-GFP fusion (SPNS1 Human)
    

    Use

    Retroviral

    Tags

    3xFlag-GFP

    Expression

    Mammalian

    Mutation

    changed glutamic acid E164 to lysine (E164K)

    Available Since

    July 12, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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17. Beta1 N391* N562* ectodomain

    Plasmid

    #221400

    Purpose

    Mammalian expression of human integrin beta1 N391* N562* ectodomain

    Depositor

    Timothy Springer

    Article

    Li et al Cell. 2024 May 14:S0092-8674(24)00475-6.

    Insert

    integrin beta1 N391* N562* ectodomain (ITGB1 Human)
    

    Tags

    AVI tag, HRV3C cleavage site, basic coil, HA tag,…

    Expression

    Mammalian

    Mutation

    codon optimized for human mature _1 residues Q1 t…

    Available Since

    June 28, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pLenti-LbCas12a-8xNLS

    Plasmid

    #209020

    Purpose

    Lentiviral vector expressing human codon-optimized LbCas12a with 8xNLS

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Insert

    LbCas12a-8xNLS-Myc-NeoR
    

    Use

    CRISPR and Lentiviral

    Tags

    MYC

    Expression

    Mammalian

    Promoter

    EF-1a

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. NSP4-mCherry

    Plasmid

    #210319

    Purpose

    Expresses SARS-CoV-2 NSP4 fused with mCherry in mammalian cells

    Depositor

    Michele Pagano

    Article

    Li et al J Virol. 2023 Sep 28:e0050723. doi: 10.1

    Insert

    SARS-CoV-2 NSP4 (ORF1ab SARS-CoV-2 isolate Wuhan-Hu-1, Human)
    

    Tags

    mCherry

    Expression

    Mammalian

    Mutation

    Many synonymous changes due to codon optimization

    Available Since

    Jan. 3, 2024

    Availability

    Academic Institutions and Nonprofits only

    

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20. FUW-crRNA-1-U6_TRE-dLbCpf1-NLS-hCTCF_K365A_R368A-HA-P2A-tagBFP

    Plasmid

    #194890

    Purpose

    Dox-inducible all-in-one lentiviral construct to express dCpf1-CTCF-K365A_R368A mutant and crRNA-1 targeting the human MECP2 locus.

    Depositor

    Shawn Liu

    Article

    Qian et al Sci Transl Med. 2023 Jan 18;15(679):eadd

    Inserts

    dLbCpf1-NLS-hCTCF_K365A_R368A
    U6-crRNA1
    

    Use

    Lentiviral

    Tags

    HA

    Mutation

    Human codon optimized catalytically inactive LbCp…

    Promoter

    TRE and U6

    Available Since

    May 9, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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