We narrowed to 88,319 results for: Mal

1. pACEMam2-TRPML1

   Plasmid

   #238303

   Purpose

   Expression of human TRPML1 in mammalian cells

   Depositor

   Pravin Mahajan

   Article

   Judith et al Structure, 2025

   Insert

   TRPML1 (MCOLN1 Human)
   

   Tags

   8xHis-3xFLAG-TEV

   Expression

   Mammalian

   Promoter

   hybrid CAG promoter

   Available Since

   June 17, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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2. pCXLE-Sox2-17-T2A-Klf4-E2A-Myc

   Plasmid

   #210016

   Purpose

   episomal S*KM (expressing mouse super-Sox + Klf4 + Myc) for integration-free naïve reset

   Depositor

   Hans Schöler

   Article

   MacCarthy et al Cell Stem Cell. 2024 Jan 4;31(1):127-147

   Insert

   Sox2-17-t2a-Klf4-e2a-cMyc (Klf4, Sox2 Mouse)
   

   Expression

   Mammalian

   Mutation

   Sox2-17 is engineered highly cooperative chimeric…

   Promoter

   CAG

   Available Since

   Dec. 14, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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3. pAAV_hSyn-SIO-stChrimsonR-EGFP-P2A-PdCO-miniWPRE

   Plasmid

   #202199

   Purpose

   Expresses bicistronically soma-targeted ChrimsonR in frame with EGFP and the optimized PdCO under control of human synapsin1 promotor after Cre-dependent recombination

   Depositor

   Ofer Yizhar

   Article

   Wietek et al Nat Methods. 2024 May 29. doi: 10.1038/s

   Has Service

   AAV1 and AAV5

   Insert

   stChrimsonR, PdCO
   

   Use

   AAV and Cre/Lox

   Tags

   EGFP and Rho1D4

   Expression

   Mammalian

   Promoter

   hSyn1

   Available Since

   July 5, 2023

   Availability

   Academic Institutions and Nonprofits only

   

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4. pLenti-CD74-ROS1 nonmutant

   Plasmid

   #183813

   Purpose

   Express CD74-ROS1 fusion (C6;R34) in mammalian cells

   Depositor

   Aaron Hata

   Article

   Lin et al Clin Cancer Res. 2021 May 15;27(10):2899

   Inserts

   ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
   CD74 molecule (CD74 Human)
   

   Use

   Lentiviral

   Tags

   The fusion protein of CD74 exon 1-6 and ROS1 exon…

   Expression

   Mammalian

   Promoter

   CMV

   Available Since

   April 29, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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5. pLenti-CD74-ROS1 G2032R

   Plasmid

   #183814

   Purpose

   Express CD74-ROS1 fusion (C6;R34) harboring ROS1 G2032R mutation in mammalian cells

   Depositor

   Aaron Hata

   Article

   Lin et al Clin Cancer Res. 2021 May 15;27(10):2899

   Inserts

   ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
   CD74 molecule (CD74 Human)
   

   Use

   Retroviral

   Tags

   The fusion protein of CD74 exon 1-6 and ROS1 exon…

   Expression

   Mammalian

   Mutation

   G2032R

   Promoter

   CMV

   Available Since

   April 27, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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6. pINDUCER-21-LCOR-P2A-HOXA9-T2A-HOXA5-IMPROVED

   Plasmid

   #154088

   Purpose

   Improved version to express LCOR, P2A, HOXA9, T2A and HOXA5 in mammalian cells.

   Depositor

   George Daley

   Article

   Sugimura et al Nature. 2017 May 17. doi: 10.1038/nature

   Insert

   Ligand Dependent Nuclear Receptor Corepressor, HOXA9, HOXA5 (LCOR, HOXA9, HOXA5 Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   Tet on

   Available Since

   May 28, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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7. pINDUCER-21-RUNX1-P2A-ERG-IMPROVED

   Plasmid

   #154089

   Purpose

   Improved version to express RUNX1, P2A, ERG in mammalian cells.

   Depositor

   George Daley

   Article

   Sugimura et al Nature. 2017 May 17. doi: 10.1038/nature

   Insert

   Runt Related Transcription Factor 1, ETS-Related Gene (RUNX1, ERG Human)
   

   Use

   Lentiviral

   Expression

   Mammalian

   Promoter

   Tet on

   Available Since

   May 28, 2021

   Availability

   Academic Institutions and Nonprofits only

   

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8. pLenti-CD74-ROS1 L2086F

   Plasmid

   #183816

   Purpose

   Express CD74-ROS1 fusion (C6;R34) harboring ROS1 L2086F mutation in mammalian cells

   Depositor

   Aaron Hata

   Article

   Lin et al Clin Cancer Res. 2021 May 15;27(10):2899

   Inserts

   ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
   CD74 molecule (CD74 Human)
   

   Use

   Lentiviral

   Tags

   The fusion protein of CD74 exon 1-6 and ROS1 exon…

   Expression

   Mammalian

   Mutation

   L2086F

   Promoter

   CMV

   Available Since

   April 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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9. pLenti-CD74-ROS1 L2000V

   Plasmid

   #183815

   Purpose

   Express CD74-ROS1 fusion (C6;R34) harboring ROS1 L2000V mutation in mammalian cells

   Depositor

   Aaron Hata

   Article

   Lin et al Clin Cancer Res. 2021 May 15;27(10):2899

   Inserts

   ROS Proto-Oncogene 1, Receptor Tyrosine Kinase (ROS1 Human)
   CD74 molecule (CD74 Human)
   

   Use

   Lentiviral

   Tags

   The fusion protein of CD74 exon 1-6 and ROS1 exon…

   Expression

   Mammalian

   Mutation

   L2000V

   Promoter

   CMV

   Available Since

   April 27, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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10. pAAV-hSyn-spCas9

    Plasmid

    #231404

    Purpose

    Expresses spCas9 from hSyn promoter

    Depositor

    Larry Young, Arjen Boender

    Article

    Schimmer et al bioRxiv 2024.07.15.603543; doi: https://

    Insert

    hSYN promoter (RIC8B Human)
    

    Use

    AAV and CRISPR

    Expression

    Mammalian

    Mutation

    Changed RSV promoter to hSYN promoter

    Promoter

    hSYN

    Available Since

    Oct. 14, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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11. pLD-puro-Cc-IFIT5_K206R-VA

    Plasmid

    #191224

    Purpose

    Lentiviral expression of human IFIT5_K206R in mammalian cells

    Depositor

    Mohan Babu

    Article

    Broderick et al Nat Commun. 2025 Jul 1;16(1):5784. doi:

    Insert

    interferon-induced protein with tetratricopeptide repeats 5 (IFIT5 Human)
    

    Use

    Lentiviral

    Tags

    3xFlag-TEVx2-6xHis-Strep x2 tag and VA tag

    Expression

    Mammalian

    Mutation

    changed Lysine 206 to Arginine (K206R)

    Promoter

    CMV

    Available Since

    April 30, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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12. AiP15571: pAAV-AiE1426m-minBG-iCre(R297T)-BGHpA (Alias: CN5571)

    Plasmid

    #230877

    Purpose

    AiE1426m is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Sst-Chodl interneurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre(R297T)
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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13. AiP15481: pAAV-AiE0140h_3xC2-minBG-iCre(R297T)-4X2C-BGHpA (Alias: CN5481)

    Plasmid

    #230876

    Purpose

    AiE0140h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal Pvalb interneurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    iCre(R297T)
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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14. AiP15646: pAAV-AiE1426m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5646)

    Plasmid

    #230884

    Purpose

    AiE1426m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in cortical and striatal Sst-Chodl neurons

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. AiP12214 - pAAV-ProB12-SYFP2-WPRE3-BGHpA (Alias: CN2214)

    Plasmid

    #208161

    Purpose

    AAV vector for SYFP2 expression in brain astrocytes

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Ben-Simon et al Cell. 2025 May 16:S0092-8674(25)00513-6.

    Insert

    SYFP2
    

    Use

    AAV

    Mutation

    NA

    Promoter

    Beta Globin minimal promoter

    Available Since

    Oct. 23, 2023

    Availability

    Academic Institutions and Nonprofits only

    

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16. AiP14573: pAAV-AiE0452h-minBG-FlpO-WPRE3-BGHpA (Alias: CN4573)

    Plasmid

    #230871

    Purpose

    AiE0452h is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    FlpO
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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17. AiP15745: pAAV-AiE0452h-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5745)

    Plasmid

    #230880

    Purpose

    AiE0452h is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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18. AiP15747: pAAV-AiE0779m_3xC2-minBG-mScarlet-WPRE3-BGHpA (Alias: CN5747)

    Plasmid

    #230882

    Purpose

    AiE0779m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal direct pathway MSNs (D1-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    mScarlet
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 27, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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19. AiP15649: pAAV-AiE0780m_3xC2-minBG-SYFP2-WPRE3-BGHpA (Alias: CN5649)

    Plasmid

    #230879

    Purpose

    AiE0780m_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal direct pathway MSNs (D1-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    SYFP2
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. AiP13985: pAAV-AiE0445h_3xC2-minBG-jRGECO1a-WPRE3-BGHpA (Alias: CN3985)

    Plasmid

    #230865

    Purpose

    AiE0445h_3xC2 is an enhancer sequence, designed to drive AAV-mediated transgene expression in striatal indirect pathway MSNs (D2-MSNs)

    Depositor

    Jonathan Ting, Allen Institute for Brain Science

    Article

    Hunker et al Neuron. 2025 May 21;113(10):1507-1524.e1

    Insert

    jRGECO1a
    

    Use

    AAV

    Expression

    Mammalian

    Available Since

    Jan. 29, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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