We narrowed to 11,455 results for: ARIA

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MAC-C Sars-CoV-2 S_D1118H

Plasmid

#194830

Purpose

Sars-CoV-2 S_D1118H in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

S_D1118H (S Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

D1118H

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 S_D138Y

Plasmid

#194831

Purpose

Sars-CoV-2 S_D138Y in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

S_D138Y (S Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

D138Y

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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HA-C Sars-CoV-2 S_D215G

Plasmid

#194832

Purpose

Sars-CoV-2 S_D215G in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

S_D215G (S Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

D215G

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 S_D614G

Plasmid

#194833

Purpose

Sars-CoV-2 S_D614G in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

S_D614G (S Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

D614G

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 S_D80A

Plasmid

#194834

Purpose

Sars-CoV-2 S_D80A in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

S_D80A (S Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

D80A

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 N_R203K+G204R

Plasmid

#194809

Purpose

Sars-CoV-2 N_R203K+G204R in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

N_R203K+G204R (N Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

R203K+G204R

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 NSP13_E341D

Plasmid

#194814

Purpose

Sars-CoV-2 NSP13_E341D in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

NSP13_E341D (ORF1ab Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

E341D

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 NSP13_P77L

Plasmid

#194815

Purpose

Sars-CoV-2 NSP13_P77L in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

NSP13_P77L (ORF1ab Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

P77L

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 NSP2_T85I

Plasmid

#194816

Purpose

Sars-CoV-2 NSP2_T85I in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

NSP2_T85I (ORF1ab Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

T85I

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 NSP3_A890D

Plasmid

#194817

Purpose

Sars-CoV-2 NSP3_A890D in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

NSP3_A890D (ORF1ab Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

A890D

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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MAC-C Sars-CoV-2 NSP3_K977Q

Plasmid

#194818

Purpose

Sars-CoV-2 NSP3_K977Q in MAC-C destination vector

Depositor

Markku Varjosalo

Article

Varjosalo et al 10 May 2024, Research Square

Insert

NSP3_K977Q (ORF1ab Sars-CoV-2)

Tags

MAC-C

Expression

Mammalian

Mutation

K977Q

Available Since

May 16, 2024

Availability

Industry, Academic Institutions, and Nonprofits

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pCDNA3-SREBP-1-GFP (A317-318; A341; A1171)

Plasmid

#204199

Purpose

Mammalian expression of SREBP-1 (isoform 1)

Depositor

Allan Weissman

Article

Yang et al J Biol Chem. 2023 Oct 12;299(12):105346.

Insert

SREBP-1 (SREBF1 Human)

Tags

3xHA, eGFP and T7x2

Expression

Mammalian

Mutation

Gly to Ala 317,318,341,1171

Available Since

April 8, 2024

Availability

Academic Institutions and Nonprofits only

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Flag-SKP1-K142R

Plasmid

#213423

Purpose

Expresses human SKP1 K142R mutant in mammalian cells

Depositor

Michele Pagano

Article

Li et al Sci Adv. 2023 Oct 13;9(41):eadh1134. doi

Insert

human Flag tagged SKP1-K142R (SKP1 Human)

Tags

Flag

Expression

Mammalian

Available Since

Feb. 28, 2024

Availability

Academic Institutions and Nonprofits only

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Flag-SKP1-97-101-5A

Plasmid

#213642

Purpose

Expresses human SKP1-97-101-5A mutant in mammalian cells

Depositor

Michele Pagano

Article

Li et al Sci Adv. 2023 Oct 13;9(41):eadh1134. doi

Insert

human Flag tagged SKP1--97-101-5A (SKP1 Human)

Tags

Flag

Expression

Mammalian

Available Since

Feb. 27, 2024

Availability

Academic Institutions and Nonprofits only

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Flag-SKP1-K163R

Plasmid

#213424

Purpose

Expresses human SKP1 K163R mutant in mammalian cells

Depositor

Michele Pagano

Article

Li et al Sci Adv. 2023 Oct 13;9(41):eadh1134. doi

Insert

human Flag tagged SKP1-K163R (SKP1 Human)

Tags

Flag

Expression

Mammalian

Available Since

Feb. 27, 2024

Availability

Academic Institutions and Nonprofits only

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pCMV-enCas12a-A3A-N57G

Plasmid

#193651

Purpose

Expression of base editor enCas12a-A3A-N57G in mammalian cells for base editing, along with non-fused EGFP fluorescence

Depositor

Liangxue Lai

Article

Chen et al Commun Biol. 2022 Nov 2;5(1):1163. doi:

Insert

dLb-enCas12a-hA3A-N57G, EGFP

Expression

Mammalian

Mutation

dLbCas12a-D156R/G532R/K538R, hAPOBEC3A-N57G

Promoter

CMV

Available Since

Feb. 20, 2024

Availability

Academic Institutions and Nonprofits only

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pCMV6-AN-DDK_S172A_M173A_V195A RAD23A

Plasmid

#201576

Purpose

Expresses a variant of human RAD23A containing mutations S172A, M173A and V195A within UBA1. Variant of plasmid pCMV6-AN-DDK_WT RAD23A

Depositor

Roger Woodgate

Article

Ashton et al J Mol Biol. 2023 Nov 5:168353. doi: 10.1

Insert

UV excision repair protein RAD23 homolog A (RAD23A Human)

Tags

FLAG

Expression

Mammalian

Mutation

Contains mutations S172A, M173A and V195A

Available Since

Nov. 8, 2023

Availability

Academic Institutions and Nonprofits only

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Stx5L(m55V)-GFP

Plasmid

#209845

Purpose

Expresses Stx5 M55V mutant fused to GFP in mammalian cells

Depositor

Geert van den Bogaart

Article

Linders et al Nat Commun. 2021 Oct 28;12(1):6227. doi:

Insert

STX5 (STX5 Human)

Tags

eGFP

Expression

Mammalian

Mutation

Changed Methionine 55 to Valine, causes loss of S…

Promoter

CMV

Available Since

Nov. 8, 2023

Availability

Academic Institutions and Nonprofits only

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pGEX-6P-1-gp78 RING

Plasmid

#185353

Purpose

RING domain-containing GST fusion protein for ubiquitination assays.

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

gp78 cytoplasmic domain (AMFR Human)

Tags

GST

Expression

Bacterial

Mutation

Stop codon after aa 393

Available Since

Oct. 16, 2023

Availability

Academic Institutions and Nonprofits only

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B-HypaR-SpCas9

Plasmid

#126764

Purpose

Expression plasmid for human codon-opt. increased fidelity Blackjack-Hypa2SpCas9 (w/o U6-sgRNA). Cleaves both 20nt and 5'-extended 21nt spacer containing sgRNAs with higher fidelity than Hypa2SpCas9.

Depositor

Ervin Welker

Article

Kulcsar et al Nat Commun. 2023 Sep 16;14(1):5746. doi:

Insert

B-Hypa2SpCas9

Use

CRISPR

Tags

3xFLAG and NLS

Expression

Mammalian

Mutation

R661A; N692A; M694A; Q695A; H698A; amino acids 10…

Promoter

CBh

Available Since

Sept. 19, 2023

Availability

Academic Institutions and Nonprofits only

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ERAP1-rs27895(C)

Plasmid

#206142

Purpose

Expresses the rs27895-C allele of ERAP1, myc-tagged.

Depositor

Dennis Ko

Article

Schott et al Cell Genom. 2022 Nov 9;2(11):100207. doi

Insert

ERAP1 (ERAP1 Human)

Available Since

Sept. 13, 2023

Availability

Academic Institutions and Nonprofits only

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pGEX-6P-1-gp78 429-611

Plasmid

#185354

Purpose

GST fusion protein for quantification of gp78 levels

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

gp78 (AMFR Human)

Tags

GST

Expression

Bacterial

Mutation

aa 429-611 only

Available Since

July 10, 2023

Availability

Academic Institutions and Nonprofits only

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pGEX-6P-1 AUP1 292-410 5E

Plasmid

#185332

Purpose

Bacterial expression of AUP1 with GST fusion protein for binding assays

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

AUP1 (AUP1 Human)

Tags

GST

Expression

Bacterial

Mutation

aa 292-410 only, with mutations R382E/Q383E/K390E…

Available Since

July 10, 2023

Availability

Academic Institutions and Nonprofits only

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pGEX-6P-1 AUP1 292-410 A397D

Plasmid

#185333

Purpose

Bacterial expression of AUP1 with GST fusion protein for binding assays

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

AUP1 (AUP1 Human)

Tags

GST

Expression

Bacterial

Mutation

aa 292-410 only, with mutation A379D

Available Since

July 10, 2023

Availability

Academic Institutions and Nonprofits only

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pEGFP-C1-G2BRgp78

Plasmid

#185344

Purpose

Expression of soluble G2BR, amino acids 575-600 of human gp78

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

gp78 aa 574-600 (G2BR) (AMFR Human)

Tags

EGFP

Expression

Mammalian

Mutation

aa 575-600 only

Available Since

Feb. 14, 2023

Availability

Academic Institutions and Nonprofits only

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pETDUET-GST-AUP1 379-410:Ube2G2

Plasmid

#185335

Purpose

Used for co-expression of the AUP1 G2BR with UBE2G2 for crystallography

Depositor

Allan Weissman

Article

Smith et al PLoS Biol. 2021 Dec 8;19(12):e3001474. d

Insert

AUP1 aa 379-410, Ube2G2 (AUP1 Mouse, Human)

Tags

GST

Expression

Bacterial

Available Since

Feb. 14, 2023

Availability

Academic Institutions and Nonprofits only

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pT7-EGFP-C1-HseIF4G1-L640AV646A_AD

Plasmid

#148520

Purpose

Mammalian Expression of HseIF4G1-L640AV646A

Depositor

Elisa Izaurralde

Article

Gruner et al Mol Cell. 2016 Nov 3;64(3):467-479. doi:

Insert

HseIF4G1-L640AV646A (EIF4G1 Human)

Expression

Mammalian

Mutation

one non silent mutation M432V (natural variant is…

Available Since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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pT7-EGFP-C1-HseIF4G1-LIVVtoAAAA_AD

Plasmid

#148521

Purpose

Mammalian Expression of HseIF4G1-LIVVtoAAAA

Depositor

Elisa Izaurralde

Article

Gruner et al Mol Cell. 2016 Nov 3;64(3):467-479. doi:

Insert

HseIF4G1-LIVVtoAAAA (EIF4G1 Human)

Expression

Mammalian

Mutation

one non silent mutation M432V (natural variant is…

Available Since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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pT7-EGFP-C1-HseIF4G1-Y619AL624AL625A_AD

Plasmid

#148522

Purpose

Mammalian Expression of HseIF4G1-Y619AL624AL625A

Depositor

Elisa Izaurralde

Article

Gruner et al Mol Cell. 2016 Nov 3;64(3):467-479. doi:

Insert

HseIF4G1-Y619AL624AL625A (EIF4G1 Human)

Expression

Mammalian

Mutation

one non silent mutation M432V (natural variant is…

Available Since

Nov. 1, 2022

Availability

Academic Institutions and Nonprofits only

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Cas9_ANKRD1_sgRNA2

Plasmid

#186669

Purpose

Plasmid containing Cas9 and ANKRD1 sgRNA2 , sgRNA sequence: cggtcagcttatatagct.

Depositor

Astrid Haase

Article

Meng et al Nucleic Acids Res. 2022 May 27. pii: 659

Insert

ANKRD1 KO sgRNA Plasmid (ANKRD1 Human)

Expression

Mammalian

Available Since

July 26, 2022

Availability

Academic Institutions and Nonprofits only

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