We narrowed to 9,317 results for: CAG

1. PIP5KL1 gRNA (BRDN0001145139)

   Plasmid

   #75822

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human PIP5KL1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   PIP5KL1 (PIP5KL1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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2. VRK3 gRNA (BRDN0001148188)

   Plasmid

   #75552

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human VRK3

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   VRK3 (VRK3 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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3. MKNK1 gRNA (BRDN0001146808)

   Plasmid

   #75512

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MKNK1

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MKNK1 (MKNK1 Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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4. NLK gRNA (BRDN0001147584)

   Plasmid

   #75482

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human NLK

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   NLK (NLK Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   July 6, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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5. MYO3B gRNA (BRDN0001145445)

   Plasmid

   #75569

   Purpose

   3rd generation lentiviral gRNA plasmid targeting human MYO3B

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Insert

   MYO3B (MYO3B Human)
   

   Use

   CRISPR and Lentiviral

   Expression

   Mammalian

   Promoter

   hU6

   Available Since

   June 24, 2016

   Availability

   Academic Institutions and Nonprofits only

   

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6. pMKO.1-puro/hFOXH1 shRNA6

   Plasmid

   #59310

   Purpose

   Knockdown of human FOXH1

   Depositor

   Shinya Yamanaka

   Article

   Takahashi et al Nat Commun. 2014 Apr 24;5:3678. doi: 10.

   Insert

   hFOXH1 shRNA (FOXH1 Human)
   

   Use

   RNAi and Retroviral

   Promoter

   hU6

   Available Since

   April 24, 2015

   Availability

   Academic Institutions and Nonprofits only

7. AAV2 for Split-PE, gRNAs + MMLV-RT(dRH)-P2A-eGFP (PKC1002)

   Plasmid

   #190112

   Purpose

   AAV2 for expression of pegRNA and ngRNA (HEKs3, CTT insertion) + MMLV-RT(dRH)-P2A-eGFP

   Depositor

   Keith Joung

   Article

   Grunewald et al Nat Biotechnol. 2023 Mar;41(3):337-343.

   Inserts

   MMLV-RT(dRH)
   U6-pegRNA(HEKs3, CTT ins)-H1-ngRNA(HEK s3)
   

   Use

   AAV

   Tags

   bpNLS and bpNLS-P2A-eGFP

   Mutation

   mutations from RT in PE2 and truncation of RNAse …

   Promoter

   EFS and U6, H1

   Available Since

   Sept. 26, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. LRG/Foxa1 e2.4

   Plasmid

   #105511

   Purpose

   Lentiviral expression of Foxa1 DNA-binding domain (exon 2) targeting sgRNA

   Depositor

   Christopher Vakoc

   Article

   Roe et al Cell. 2017 Aug 24;170(5):875-888.e20. do

   Insert

   Foxa1 (sgRNA, e2.4)
   

   Use

   Lentiviral

   Available Since

   Feb. 12, 2018

   Availability

   Academic Institutions and Nonprofits only

   

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9. pAAV-HDR-mEGFP-camk2a

   Plasmid

   #104589

   Purpose

   AAV vector including gRNA expression cassette and mEGFP knock-in donor targeting mouse camk2a

   Depositor

   Ryohei Yasuda

   Article

   Nishiyama et al Neuron. 2017 Oct 18. pii: S0896-6273(17)

   Insert

   calcium/calmodulin-dependent protein kinase II alpha (Camk2a Mouse)
   

   Use

   AAV, CRISPR, and Mouse Targeting

   Promoter

   None

   Available Since

   Dec. 20, 2017

   Availability

   Academic Institutions and Nonprofits only

   

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10. AAVS1-PDL1

    Plasmid

    #159280

    Purpose

    Human AAVS1 targeting vector for knockin of a CAGGS promoter-driven human PDL1/CD274 (cloned between AgeI and PacI). Targeted cells will be puromycin resistant.

    Depositor

    Rudolf Jaenisch

    Article

    Ma et al Cell Rep Med. 2020 Sep 22;1(6):100097. d

    Insert

    Human PDL1/CD274 (CD274 Human)
    

    Use

    AAV; S1 knockin donor vector

    Expression

    Mammalian

    Promoter

    CAGGS

    Available Since

    Sept. 25, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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11. MtPT4-p3

    Plasmid

    #160003

    Purpose

    Multigene construct containing the betalain pigment biosynthetic genes under the control of the MtPT4 promoter for visualisation of arbuscular mycorrhizal colonisation in Medicago truncatula roots.

    Depositor

    Sam Brockington

    Article

    Timoneda et al PLoS Biol. 2021 Jul 14;19(7):e3001326. d

    Inserts

    DsRed (reverse orientation)
    DODAα1
    CYP76AD1
    cDOPA5GT
    

    Expression

    Plant

    Promoter

    Arabidopsis thaliana Ubiquitin 10 Promoter (AtUb1…

    Available Since

    July 13, 2021

    Availability

    Academic Institutions and Nonprofits only

    

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12. TRIM28 gRNA (BRDN0001146162)

    Plasmid

    #76142

    Purpose

    3rd generation lentiviral gRNA plasmid targeting human TRIM28

    Depositor

    John Doench, David Root

    Article

    Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

    Insert

    TRIM28 (TRIM28 Human)
    

    Use

    CRISPR and Lentiviral

    Expression

    Mammalian

    Promoter

    hU6

    Available Since

    July 6, 2016

    Availability

    Academic Institutions and Nonprofits only

    

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13. pSuper-Retro-Puro-Drp1-shRNA

    Plasmid

    #99385

    Purpose

    Expresses shRNA against human Drp1 from puromycin resistance retroviral vector

    Depositor

    David Kashatus

    Article

    Sweatt et al Mol Syst Biol. 2024 Sep 27. doi: 10.1038

    Insert

    Dynamin-1-like protein (DNM1L Human)
    

    Use

    RNAi and Retroviral

    Promoter

    H1

    Available Since

    Sept. 5, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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14. pLKO-Tet-On shYap1-4

    Plasmid

    #193670

    Purpose

    Tet inducible knockdown of Yap1

    Depositor

    William Hahn

    Article

    Kim et al Dev Cell. 2022 Jan 24;57(2):212-227.e8.

    Insert

    Yap1 (Yap1 Mouse)
    

    Use

    Lentiviral

    Available Since

    Dec. 20, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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15. VE-cad KI gRNA1

    Plasmid

    #92310

    Purpose

    CRISPR-GFP-gRNA for cutting VEcad

    Depositor

    Sean Palecek

    Article

    Bao et al Bioeng Transl Med. 2017 Jun;2(2):191-201

    Insert

    VEcad KI gRNA1 (CDH5 Human)
    

    Use

    CRISPR

    Expression

    Mammalian

    Promoter

    U6

    Available Since

    July 7, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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16. tet_pLKO.1_puro_shNRF2 #2

    Plasmid

    #136585

    Purpose

    Expresses an inducible short hairpin targeting human NRF2 sequence

    Depositor

    Kevin Janes

    Article

    Pereira et al Sci Signal. 2020 Apr 14;13(627). pii: 13

    Insert

    shNRF2v2 (NFE2L2 Human)
    

    Use

    Lentiviral

    Expression

    Mammalian

    Available Since

    June 13, 2020

    Availability

    Academic Institutions and Nonprofits only

    

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17. LV-indLS2

    Plasmid

    #123068

    Purpose

    Lentiviral construct that delivers a tamoxifen inducible Cre. Upon recombination, luc2 and mStrawberry express. Used to image spontaneous tumorigenesis or subclonal cell populations in vivo.

    Depositor

    Kevin Brindle

    Article

    Rodriguez et al J Pathol. 2014 Mar;232(4):449-57. doi: 1

    Inserts

    CreERT2 with intron
    Firefly luciferase
    mStrawberry
    

    Use

    Lentiviral and Luciferase; Fluorescence

    Expression

    Mammalian

    Mutation

    synthetic intron added as indicated

    Promoter

    CAGGS (after Cre mediated inversion) and CAGGS (f…

    Available Since

    April 3, 2019

    Availability

    Academic Institutions and Nonprofits only

    

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18. pFRT/TO/FLAG/HA-DEST TNRC6A

    Plasmid

    #19883

    Depositor

    Thomas Tuschl

    Article

    Landthaler et al RNA. 2008 Dec;14(12):2580-96. doi: 10.12

    Insert

    Trinucleotide repeat containing 6A (TNRC6A Human)
    

    Tags

    FLAG/HA

    Expression

    Mammalian

    Available Since

    Dec. 31, 2008

    Availability

    Academic Institutions and Nonprofits only

    

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19. pColdI-DDX3_helicase_core

    Plasmid

    #233618

    Purpose

    Expression of His-tagged helicase core region of DDX3X in E.coli

    Depositor

    Shintaro Iwasaki

    Article

    Chen et al Cell Chem Biol. 2021 Apr 15;28(4):475-48

    Insert

    DDX3X helicase core WT (DDX3X Human)
    

    Tags

    His6

    Expression

    Bacterial

    Available Since

    March 11, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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20. pRN3P-HA-Suv4-20h1mut

    Plasmid

    #86690

    Purpose

    For transcription of of Suv4-20h1mut mRNA preceded by an HA-tag in 5'

    Depositor

    Maria-Elena Torres-Padilla

    Article

    Eid et al Genes Dev. 2016 Nov 15;30(22):2513-2526.

    Insert

    histone-lysine N-methyltransferase KMT5B mutant (Kmt5b Mouse)
    

    Tags

    HA

    Mutation

    mutated region NHDC (asparagine 273 to cysteine 2…

    Promoter

    T3

    Available Since

    April 26, 2017

    Availability

    Academic Institutions and Nonprofits only

    

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