We narrowed to 30,903 results for: LIS;

1. pBOBI TP53 S46D

   Plasmid

   #213002

   Purpose

   expresses human P53

   Depositor

   Sheng-cai Lin

   Article

   Wu et al Cell Res. 2023 Nov;33(11):835-850. doi:

   Insert

   P53 (TP53 Human)
   

   Expression

   Mammalian

   Mutation

   S46D

   Promoter

   cmv

   Available Since

   April 29, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pACYC-T7-SpCas9(BspMI/SapI/BsaI_cassettes)-T7-gRNA1 (BPK1807)

   Plasmid

   #223065

   Purpose

   Dual pT7 entry plasmid for SpCas9(6AA) library; bacterial expression plasmid with type IIS RE cassettes around D1135/S1136, G1218/E1219, R1335/T1337 (precursor to MMW94). Expresses a gRNA.

   Depositor

   Benjamin Kleinstiver

   Article

   Silverstein et al Nature. 2025 Apr 22. doi: 10.1038/s41586

   Insert

   entry vector for human codon opt. bacterial expr. plasmid for SpCas9(6AA_NNS) library, with gRNA targeting EGFP site 1
   

   Use

   CRISPR

   Tags

   NLS(SV40)-3xFLAG

   Expression

   Bacterial

   Mutation

   Three regions of SpCas9 encode type IIS restricti…

   Promoter

   Dual T7

   Available Since

   April 23, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pRSITEP-puro-shWRN1

   Plasmid

   #125783

   Purpose

   DOX-inducible expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN1 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pBOBI N-HA AXIN1

   Plasmid

   #213000

   Purpose

   expresses mouse AXIN1

   Depositor

   Sheng-cai Lin

   Article

   Wu et al Cell Res. 2023 Nov;33(11):835-850. doi:

   Insert

   AXIN1 (Axin1 Mouse)
   

   Tags

   HA

   Expression

   Mammalian

   Promoter

   cmv

   Available Since

   Feb. 28, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pRSITEP-puro-shWRN1-C911

   Plasmid

   #125784

   Purpose

   a seed-matched control for pRSITEP-puro-shWRN1

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN1-C911 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pRSITEP-puro-shWRN2

   Plasmid

   #125785

   Purpose

   DOX-inducible expression of a short-hairpin RNA targeting human WRN

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   Aug. 21, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pGL3-basic-FTO promoter_WT

   Plasmid

   #108922

   Purpose

   The core promoter region of FTO was inserted into pGL3 basic vector

   Depositor

   Jianjun Chen

   Article

   Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

   Insert

   FTO (FTO Human)
   

   Tags

   NA

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pGL3-basic-FTO promoter_Mut

   Plasmid

   #108923

   Purpose

   The core promoter region of FTO with mutant CEBPA binding sites was inserted into pGL3 basic vector

   Depositor

   Jianjun Chen

   Article

   Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

   Insert

   FTO (FTO Human)
   

   Tags

   NA

   Expression

   Mammalian

   Mutation

   NA

   Available Since

   May 30, 2018

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

9. pRSITEP-puro-shWRN2-C911

   Plasmid

   #125786

   Purpose

   a seed-matched control for pRSITEP-puro-shWRN2

   Depositor

   Francisca Vazquez

   Article

   Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

   Insert

   shWRN2 (WRN Human)
   

   Use

   RNAi

   Available Since

   June 27, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLKO.1-puro-shWRN1

    Plasmid

    #125781

    Purpose

    constitutive expression of a short-hairpin RNA targeting human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shWRN1 (WRN Human)
    

    Use

    RNAi

    Available Since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pLKO.1-puro-shWRN2

    Plasmid

    #125782

    Purpose

    constitutive expression of a short-hairpin RNA targeting human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shWRN2 (WRN Human)
    

    Use

    RNAi

    Available Since

    June 27, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pXPR_BRD003 PSMB5 guide 1

    Plasmid

    #117073

    Purpose

    single guide RNA targeting PSMB5; guide 1

    Depositor

    William Hahn

    Article

    Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

    Insert

    LMPX (PSMB5 Human)
    

    Use

    CRISPR

    Promoter

    hU6

    Available Since

    March 13, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pXPR_BRD003-sgWRN1

    Plasmid

    #125771

    Purpose

    constitutive expression of a guide RNA targeting human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgWRN1 (WRN Human)
    

    Use

    CRISPR

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pXPR_BRD003-sgWRN-EIJ

    Plasmid

    #125774

    Purpose

    constitutive expression of a guide RNA targeting an exon-intron junction of human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgWRN-EIJ (WRN Human)
    

    Use

    CRISPR

    Available Since

    June 11, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLKO.1-puro-shPSMD2

    Plasmid

    #125779

    Purpose

    constitutive expression of a short-hairpin RNA targeting human PSMD2 (RNAi positive control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    shPSMD2 (PSMD2 Human)
    

    Use

    RNAi

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pXPR_BRD003-sgWRN2

    Plasmid

    #125772

    Purpose

    constitutive expression of a guide RNA targeting human WRN

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgWRN2 (WRN Human)
    

    Use

    CRISPR

    Available Since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pXPR_BRD051-sgCh2-2

    Plasmid

    #125775

    Purpose

    constitutive expression of a guide RNA targeting an intergenic region of human chromosome 2 (CRISPR cutting control) and S. pyogenes Cas9

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgCh2-2
    

    Use

    CRISPR

    Available Since

    June 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pMIR-REPORT-MYC CDS_WT

    Plasmid

    #108924

    Purpose

    MYC mRNA CDS region with wild type m6A motifs was inserted into pMIR-REPORT vector

    Depositor

    Jianjun Chen

    Article

    Su et al Cell. 2018 Jan 11;172(1-2):90-105.e23. d

    Insert

    MYC (MYC Human)
    

    Expression

    Mammalian

    Promoter

    CMV

    Available Since

    May 30, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pXPR_BRD003-sgPOLR2D

    Plasmid

    #125769

    Purpose

    constitutive expression of a guide RNA targeting human POLR2D (CRISPR positive control)

    Depositor

    Francisca Vazquez

    Article

    Chan et al Nature. 2019 Apr 10. pii: 10.1038/s41586

    Insert

    sgPOLR2D (POLR2D Human)
    

    Use

    CRISPR

    Available Since

    May 29, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pXPR_BRD003 PSMB5 guide 2

    Plasmid

    #117074

    Purpose

    single guide RNA targeting PSMB5; guide 2

    Depositor

    William Hahn

    Article

    Hong et al Elife. 2019 Mar 12;8. pii: 44161. doi: 1

    Insert

    LMPX (PSMB5 Human)
    

    Use

    CRISPR

    Promoter

    hU6

    Available Since

    March 13, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge