We narrowed to 7,500 results for: PAC

1. pcDNA3.1(-).TagRFP.T-2A-V5-T181D.Tau2N4R-WPRE

   Plasmid

   #226394

   Purpose

   Expresses tau propagation ORF with V5 tag on T181D mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   T181D, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

2. pcDNA3.1(-).TagRFP.T-2A-V5-T231D.Tau2N4R-WPRE

   Plasmid

   #226395

   Purpose

   Expresses tau propagation ORF with V5 tag on T231D mutant 2N4R tau

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   TagRFP.T.2A.V5

   Expression

   Mammalian

   Mutation

   T231D, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

3. pET28.His.3C.20D3Q.Tau2N4R

   Plasmid

   #226397

   Purpose

   Expresses his-tagged, 3C-cleavable 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   His.3C

   Expression

   Bacterial

   Mutation

   20D3Q, Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. pET28.His.3C.8D2Q.Tau2N4R

   Plasmid

   #226398

   Purpose

   Expresses his-tagged, 3C-cleavable 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   His.3C

   Expression

   Bacterial

   Mutation

   8D2Q.Tau2N4R

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. pET28.His.3C.86b.Tau2N4R

   Plasmid

   #226399

   Purpose

   Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged WT 2N4R tau for recombinant protein production in bacteria

   Depositor

   Bradley Hyman

   Article

   Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

   Insert

   Tau2N4R (MAPT Human, synthetic)
   

   Use

   Tags

   His.3C.86b

   Expression

   Bacterial

   Mutation

   Promoter

   Available since

   Nov. 14, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

6. pSDC803_IKZF1_mutant

   Plasmid

   #224113

   Purpose

   Insect cell expression vector for IKZF1 mutant for CRBN cryoEM pre-blotting

   Depositor

   Eric Fischer

   Article

   Mercer et al Science. 2024 Mar 15;383(6688):eadk4422.

   Insert

   IKZF1 (IKZF1 Human)
   

   Use

   Tags

   Flag-TEV

   Expression

   Insect

   Mutation

   Residues 140-196, Q146A and G151N

   Promoter

   polyhedrin

   Available since

   Aug. 23, 2024

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

7. pLJM5-WT PHGDH

   Plasmid

   #83901

   Purpose

   stable overexpression

   Depositor

   David Sabatini

   Article

   Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

   Insert

   Phosphoglycerate dehydrogenase (PHGDH Human)
   

   Use

   Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   CMV

   Available since

   Oct. 20, 2016

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

8. pET30-2-PHGDH

   Plasmid

   #83907

   Purpose

   stable overexpression

   Depositor

   David Sabatini

   Article

   Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

   Insert

   Phosphoglycerate dehydrogenase (PHGDH Human)
   

   Use

   Tags

   6x His tags

   Expression

   Bacterial

   Mutation

   Promoter

   T7

   Available since

   Oct. 21, 2016

   Availability

   Academic Institutions and Nonprofits only

9. N-Terminal Split Cas9 D10A Nickase with GyrA intein

   Plasmid

   #58695

   Purpose

   Expresses N-terminus of D10A SpCas9 nickase domain fused to a GyrA intein, flanked by ITRs for AAV packaging. Combine with C-Terminal Split Cas9 Gyra Intein for full length SpCas9 nickase production

   Depositor

   Gang Bao

   Article

   Fine et al Sci Rep. 2015 Jul 1;5:10777. doi: 10.103

   Insert

   D10A Nickase humanized S. pyogenes Cas9 with Gyra Nsplit Intein
   

   Use

   AAV and CRISPR

   Tags

   GyrA Nsplit Intein, HA Tag, and NLS

   Expression

   Mammalian

   Mutation

   D10A nickase converting mutation to SpCas9

   Promoter

   CBh

   Available since

   Sept. 25, 2014

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pLentiCRISPRv1-sgPHGDH-G5

    Plasmid

    #83913

    Purpose

    stable knockout

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    Phosphoglycerate dehydrogenase (PHGDH Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    Oct. 24, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

11. pcDNA3.1(+)-FluoSTEP-ICUE

    Plasmid

    #181845

    Purpose

    Genetically encoded FRET-based sensor for monitoring cAMP dynamics near a protein of interest. Must pair with GFP11-tagged POI to reconstitute donor fluorescence.

    Depositor

    Jin Zhang

    Article

    Zhang et al Cell. 2020 Sep 17;182(6):1531-1544.e15.

    Insert

    FluoSTEP-ICUE (RAPGEF3 Human)
    

    Use

    Tags

    mRuby2 and sfGFP(1-10)

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    July 6, 2022

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. pET30-2-GPD1

    Plasmid

    #83911

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    glycerol-3-phosphate dehydrogenase 1 (GPD1 Human)
    

    Use

    Tags

    6x His tags

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Oct. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

13. pLentiCRISPRv1-sgAAVS1

    Plasmid

    #83906

    Purpose

    stable knockout

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    adeno-associated virus integration site 1 (AAVS1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    Oct. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pET30-2-PHGDH-C234S

    Plasmid

    #107724

    Purpose

    Expression of PHGDH C234S in bacteria

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    PHGDH (PHGDH Human)
    

    Use

    Tags

    Expression

    Bacterial

    Mutation

    C234S

    Promoter

    Available since

    April 18, 2018

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

15. pLJM5-C234S PHGDH

    Plasmid

    #83902

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    Phosphoglycerate dehydrogenase (PHGDH Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    quikchanged cysteine 234 to serine

    Promoter

    CMV

    Available since

    Oct. 20, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pLJM5-mSHMT1

    Plasmid

    #83904

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    Serine hydroxymethyltransferase 1 (Shmt1 Mouse)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CMV

    Available since

    Oct. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pDONR223-SCYL3

    Plasmid

    #23680

    Depositor

    David Root, William Hahn

    Article

    Johannessen et al Nature. 2010 Dec 16;468(7326):968-72. do

    Insert

    SCYL3 (SCYL3 Human)
    

    Use

    Gateway donor vector

    Tags

    Expression

    Mutation

    Promoter

    Available since

    July 30, 2010

    Availability

    Academic Institutions and Nonprofits only

18. pET30-2-GPD1L

    Plasmid

    #83912

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    glycerol-3-phosphate dehydrogenase 1-like (GPD1L Human)
    

    Use

    Tags

    6x His tags

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Oct. 24, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pLentiCRISPRv1-sgSHMT1-G3

    Plasmid

    #83903

    Purpose

    stable knockout

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    Serine hydroxymethyltransferase 1 (SHMT1 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    hU6

    Available since

    Oct. 31, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pET28.His.3C.86b.8D2Q.Tau2N4R

    Plasmid

    #226400

    Purpose

    Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged 8D2Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau (MAPT Human, synthetic)
    

    Use

    Tags

    His.3C.86b

    Expression

    Bacterial

    Mutation

    8D2Q.Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

21. pET28.His.3C.86b.20D3Q.Tau2N4R

    Plasmid

    #226401

    Purpose

    Expresses his-tagged, 3C-cleavable, 86b (split luciferase fragment)-tagged 20D3Q mutant 2N4R tau for recombinant protein production in bacteria

    Depositor

    Bradley Hyman

    Article

    Dickson et al J Neuropathol Exp Neurol. 2025 Jun 1;84(

    Insert

    Tau2N4R (MAPT Human, synthetic)
    

    Use

    Tags

    His.3C.86b

    Expression

    Bacterial

    Mutation

    20D3Q, Tau2N4R

    Promoter

    Available since

    Nov. 14, 2024

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

22. pET30-2-GAPDH

    Plasmid

    #83910

    Purpose

    stable overexpression

    Depositor

    David Sabatini

    Article

    Pacold et al Nat Chem Biol. 2016 Jun;12(6):452-8. doi

    Insert

    glyceraldehyde-3-phosphate dehydrogenase (GAPDH Human)
    

    Use

    Tags

    6x His tags

    Expression

    Bacterial

    Mutation

    Promoter

    T7

    Available since

    Oct. 21, 2016

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

23. pCW-codon optimized catalytically inactive PHGDH

    Plasmid

    #154903

    Purpose

    Expresses codon optimized catalytically inactive PHGDH in mammalian cells

    Depositor

    Michael Pacold

    Article

    Ngo et al Cancer Discov. 2020 Sep;10(9):1352-1373.

    Insert

    Phosphoglycerate dehydrogenase (PHGDH Human)
    

    Use

    Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Three mutations: D175N, R236K, H283A

    Promoter

    TRE

    Available since

    July 30, 2020

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

24. pLV-dCas9-p300-P2A-PuroR

    Plasmid

    #83889

    Purpose

    Lentiviral Sp dCas9-p300-P2A-PuroR

    Depositor

    Charles Gersbach

    Article

    Klann et al Nat Biotechnol. 2017 Apr 3. doi: 10.1038

    Inserts

    S.pyogenes dCas9 with c-terminal human p300 Core effector fusion (aa 1048-1664 of human p300) (EP300 Human, Synthetic, S. pyogenes)
    pac from Streptomyces alboniger
    

    Use

    CRISPR and Lentiviral

    Tags

    Flag and nucleoplasmin NLS

    Expression

    Mammalian

    Mutation

    D10A; H840A in S.pyogenes Cas9

    Promoter

    EFS

    Available since

    April 6, 2017

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

25. pMD2.G

    Plasmid

    #12259

    Purpose

    VSV-G envelope expressing plasmid

    Depositor

    Didier Trono

    Insert

    VSV G
    

    Use

    Lentiviral; Envelope

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    Available since

    Aug. 4, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

26. pRS314-URA3

    Plasmid

    #11004

    Depositor

    Francisco Malagon

    Insert

    URA3 (URA3 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    April 28, 2006

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

27. YEplac181-BUD32

    Plasmid

    #10997

    Depositor

    Francisco Malagon

    Insert

    BUD32 (BUD32 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 16, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

28. pRS415-RSC2

    Plasmid

    #11001

    Depositor

    Francisco Malagon

    Insert

    RSC2 (RSC2 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

29. YEplac181-NAR1

    Plasmid

    #10999

    Depositor

    Francisco Malagon

    Insert

    NAR1 (NAR1 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 16, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

30. YEplac181-RSC2

    Plasmid

    #11000

    Depositor

    Francisco Malagon

    Insert

    RSC2 (RSC2 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 16, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

31. pRS415-BUD32

    Plasmid

    #10991

    Depositor

    Francisco Malagon

    Insert

    BUD32 (BUD32 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

32. pRS415-NAR1

    Plasmid

    #10995

    Depositor

    Francisco Malagon

    Insert

    NAR1 (NAR1 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

33. pRS415-SSM1

    Plasmid

    #11003

    Depositor

    Francisco Malagon

    Insert

    SSM1 (SDT1 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

34. YEplac181-SSM1

    Plasmid

    #11002

    Depositor

    Francisco Malagon

    Insert

    SSM1 (SDT1 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 16, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

35. pGL1_108

    Plasmid

    #210692

    Purpose

    Level 1 plasmid, barcoded ORI

    Depositor

    Charlie Gilbert, Cultivarium Tools, Nili Ostrov

    Insert

    pIM13 with barcode 28
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

36. pGEX6P1-Syndapin1fl

    Plasmid

    #36859

    Depositor

    Yvonne Groemping

    Insert

    Syndapin1 (Pacsin1 Mouse)
    

    Use

    Tags

    GST

    Expression

    Bacterial

    Mutation

    Promoter

    Available since

    July 17, 2012

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

37. pRS415-SPT6

    Plasmid

    #10993

    Depositor

    Francisco Malagon

    Insert

    SPT6 (SPT6 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

38. pRS415-KEX2

    Plasmid

    #10996

    Depositor

    Francisco Malagon

    Insert

    KEX2 (KEX2 Budding Yeast)
    

    Use

    Tags

    Expression

    Bacterial and Yeast

    Mutation

    Wild type

    Promoter

    Available since

    Dec. 29, 2005

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

39. pGL1_110

    Plasmid

    #210694

    Purpose

    Level 1 plasmid, barcoded ORI

    Depositor

    Charlie Gilbert, Cultivarium Tools, Nili Ostrov

    Insert

    pTHT15 with barcode 30
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

40. pGL1_109

    Plasmid

    #210693

    Purpose

    Level 1 plasmid, barcoded ORI

    Depositor

    Charlie Gilbert, Cultivarium Tools, Nili Ostrov

    Insert

    pMB1 with barcode 29
    

    Use

    Synthetic Biology

    Tags

    Expression

    Mutation

    Promoter

    Available since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge