We narrowed to 4,335 results for: U6 gRNA

1. LCV2_mCherry_Luciferase_sgRNA

   Plasmid

   #155109

   Purpose

   lentiviral plasmid expressing mCherry, Cas9 and a gRNA targeting Luciferase

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   Luciferase_sgRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6 promoter

   Available since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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2. LCV2_Luciferase_sgRNA

   Plasmid

   #155094

   Purpose

   lentiviral plasmid expressing Cas9 and gRNA targeting Luciferase

   Depositor

   Jason Moffat

   Article

   Aregger et al Nat Metab. 2020 Jun;2(6):499-513. doi: 1

   Insert

   Luciferase_sgRNA
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6 promoter

   Available since

   Aug. 7, 2020

   Availability

   Academic Institutions and Nonprofits only

   

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3. AAV-U6-sgNT-2-EF1a-LibVec

   Plasmid

   #239593

   Purpose

   expresses non-targeting (NT) guide#2

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   NT (non-targeting guide)
   

   Use

   AAV; To deliver a non-targeting guide (serving as…

   Tags

   Expression

   Mutation

   Promoter

   hU6

   Available since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

4. AAV-U6-sgNT-1-EF1a-LibVec

   Plasmid

   #239592

   Purpose

   expresses non-targeting (NT) guide#1

   Depositor

   Andreas Moor

   Article

   Borrelli et al Nature. 2024 Aug;632(8024):411-418. doi:

   Insert

   NT (non-targeting guide)
   

   Use

   AAV; To deliver a non-targeting guide (serving as…

   Tags

   Expression

   Mutation

   Promoter

   hU6

   Available since

   July 11, 2025

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

5. mU6-sgRNA-CLTA-mCherry

   Plasmid

   #240637

   Purpose

   Vector for expressing an sgRNA targeting CLTA promoter from the mouse U6 promoter and a puromycin resistance cassette and BFP from the EF1Alpha promoter.

   Depositor

   James Nuñez

   Article

   Xu et al Nat Commun. 2025 Aug 26;16(1):7948. doi:

   Insert

   puro-T2A-mCherry
   

   Use

   CRISPR

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   Available since

   Aug. 19, 2025

   Availability

   Academic Institutions and Nonprofits only

   

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6. AAVi U6_gRNA CMV_SadCas9-KRAB

   Plasmid

   #214609

   Purpose

   All-in-one AAVi plasmid expressing S. aureus dCas9-KRAB with sgRNA cassette

   Depositor

   Ralf Gilsbach

   Article

   Laurette et al Circ Res. 2023 Dec 22. doi: 10.1161/CIRC

   Inserts

   gRNA
   SadCas9
   

   Use

   AAV

   Tags

   NP NLS and SV40 NLS

   Expression

   Mammalian

   Mutation

   D10A, N580A

   Promoter

   CMV and U6

   Available since

   March 12, 2024

   Availability

   Academic Institutions and Nonprofits only

   

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7. pegRNA-GFP>BFP_Y66H-NGG

   Plasmid

   #185480

   Purpose

   pegRNA plasmid in order to make a Y66H (TAC>CAT) conversion in the GFP gene, creating a BFP gene.

   Depositor

   Sabine Fuchs

   Article

   Schene et al Nat Commun. 2022 Mar 1;13(1):1028. doi:

   Insert

   GFP>BFP_Y66H-pegRNA
   

   Use

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   July 28, 2022

   Availability

   Academic Institutions and Nonprofits only

   

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8. pX330 Human 3' HP1a gRNA

   Plasmid

   #127907

   Purpose

   WT Cas9 Vector targeting the 3' end of the human HP1a gene

   Depositor

   Mark Groudine

   Article

   Strom et al Elife. 2021 Jun 9;10. pii: 63972. doi: 1

   Insert

   gRNA for Human 3' HP1a
   

   Use

   CRISPR

   Tags

   Expression

   Mutation

   Promoter

   Available since

   Sept. 12, 2019

   Availability

   Academic Institutions and Nonprofits only

   

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9. pKLV2-U6gRNA5(Pou5f1-g2)-PGKpuroBFP-W

   Plasmid

   #105036

   Purpose

   Lentiviral gRNA plasmid targeting mouse Pou5f1 , co-expression of TagBFP

   Depositor

   Kosuke Yusa

   Article

   Li et al Cell Rep. 2018 Jul 10;24(2):489-502. doi

   Insert

   Pou5f1 (Pou5f1 Mouse)
   

   Use

   CRISPR and Lentiviral

   Tags

   Expression

   Mammalian

   Mutation

   Promoter

   U6

   Available since

   Sept. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

   

   Enlarge

10. pX459-HypaCas9-mR2-ACTB_sgRNA

    Plasmid

    #183884

    Purpose

    pX459V2.0-HypaCas9 plasmid with mRuby2 reporter and ACTB sgRNA for N-terminal tagging of beta-actin in human cells.

    Depositor

    Alisa Piekny

    Article

    Husser et al Open Biol. 2022 Nov;12(11):220247. doi:

    Insert

    ACTB sgRNA spacer (ACTB Human)
    

    Use

    CRISPR

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    May 23, 2022

    Availability

    Academic Institutions and Nonprofits only

    

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11. pKLV2-U6gRNA5(Stat3)-PGKpuroBFP-W

    Plasmid

    #105027

    Purpose

    Lentiviral gRNA plasmid targeting mouse Stat3 , co-expression of TagBFP

    Depositor

    Kosuke Yusa

    Article

    Li et al Cell Rep. 2018 Jul 10;24(2):489-502. doi

    Insert

    Stat3 (Stat3 Mouse)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    U6

    Available since

    Sept. 4, 2019

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

12. AAV_3xgRNA;PTENA, p53B,SMAD4A_CAG_FlPO_synthPA

    Plasmid

    #68346

    Purpose

    Used to produce AAV expressing the FlpO recombinase and pig gRNA towards 3 tumor suppressors: PTEN, p53 and SMAD4

    Depositor

    Jannik Elverløv-Jakobsen

    Article

    Berthelsen et al Cancers (Basel). 2021 Jun 16;13(12). pii

    Inserts

    3xgRNA;PTENA, p53B,SMAD4A
    FlPO
    

    Use

    AAV; Flp/frt

    Tags

    Expression

    Mammalian

    Mutation

    Promoter

    CAG and U6

    Available since

    Dec. 2, 2015

    Availability

    Academic Institutions and Nonprofits only

    

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13. pdU6-2_sgRNA1-5-HT2AR-isoformD

    Plasmid

    #221823

    Purpose

    Plasmid to express gRNA1 (tccttctggcgcaaacacgg) for editing at the end of Drosophila 5-HT2AR isoform D coding frame

    Depositor

    Quentin Gaudry

    Article

    Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

    Insert

    d5-HT2AR isoform D gRNA1 (5-HT2 Fly)
    

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Drosophila U6 promoter

    Available since

    Aug. 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

14. pdU6-2_sgRNA2-5-HT2AR-isoformD

    Plasmid

    #221824

    Purpose

    Plasmid to express gRNA2 (ctgaagacataattacgtgg) for editing at the end of Drosophila 5-HT2AR isoform D coding frame

    Depositor

    Quentin Gaudry

    Article

    Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

    Insert

    d5-HT2AR isoform D gRNA2 (5-HT2 Fly)
    

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    zebrafish U6 promoter (U6b)

    Available since

    Aug. 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

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15. pdU6-2_sgRNA1-5-HT2AR-isoformBFH

    Plasmid

    #221825

    Purpose

    Plasmid to express gRNA1 (cgctatcggtctgtgacaga) for editing at the end of Drosophila 5-HT2AR isoforms B, F and H coding frame

    Depositor

    Quentin Gaudry

    Article

    Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

    Insert

    d5-HT2AR isoforms BFH gRNA1 (5-HT2 Fly)
    

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    zebrafish U6 promoter (U6b)

    Available since

    Aug. 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

16. pdU6-2_sgRNA2-5-HT2AR-isoformBFH

    Plasmid

    #221826

    Purpose

    Plasmid to express gRNA2 (ggaaaagccgctaattacag) for editing at the end of Drosophila 5-HT2AR isoforms B, F and H coding frame

    Depositor

    Quentin Gaudry

    Article

    Mallick et al bioRxiv [Preprint]. 2024 Apr 14:2024.04.

    Insert

    d5-HT2AR isoforms BFH gRNA2 (5-HT2 Fly)
    

    Use

    CRISPR

    Tags

    Expression

    Insect

    Mutation

    Promoter

    Drosophila U6 promoter

    Available since

    Aug. 18, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

17. pKLV2-U6gRNA5(hEGFR_2b)-PGKpuro2ABFP-W

    Plasmid

    #208432

    Purpose

    Lentiviral gRNA plasmid targeting human EGFR gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Heliyon. 2024 Oct 22;10(21):e39677. doi:

    Insert

    EGFR (EGFR Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

18. pKLV2-U6gRNA5(hRNF31_2b)-PGKpuro2ABFP-W

    Plasmid

    #208415

    Purpose

    Lentiviral gRNA plasmid targeting human RNF31 gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

    Insert

    RNF31 (RNF31 Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

19. pKLV2-U6gRNA5(hXIAP_1k)-PGKpuro2ABFP-W

    Plasmid

    #208420

    Purpose

    Lentiviral gRNA plasmid targeting human XIAP gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

    Insert

    XIAP (XIAP Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge

20. pKLV2-U6gRNA5(hXIAP_2b)-PGKpuro2ABFP-W

    Plasmid

    #208421

    Purpose

    Lentiviral gRNA plasmid targeting human XIAP gene, co-expression of BFP tag

    Depositor

    Sok Ching Cheong

    Article

    Chai et al Cancer Res Commun. 2024 Nov 1;4(11):2919

    Insert

    XIAP (XIAP Human)
    

    Use

    CRISPR and Lentiviral

    Tags

    Expression

    Mammalian

    Mutation

    N/A

    Promoter

    human U6

    Available since

    July 1, 2025

    Availability

    Academic Institutions and Nonprofits only

    

    Enlarge