We narrowed to 75,796 results for: Rest
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Plasmid#82770PurposeGateway Donor vector containing ATF2, part of the Target Accelerator Plasmid Collection.DepositorInsertATF2 (ATF2 Human)
UseGateway entry vectorTagsExpressionMutationT339APromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_IDH2_p.R188W
Plasmid#82775PurposeGateway Donor vector containing IDH2, part of the Target Accelerator Plasmid Collection.DepositorInsertIDH2 (IDH2 Human)
UseGateway entry vectorTagsExpressionMutationR188WPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_FBXW7_p.P620R
Plasmid#82780PurposeGateway Donor vector containing FBXW7 , part of the Target Accelerator Plasmid Collection.DepositorInsertFBXW7 (FBXW7 Human)
UseGateway entry vectorTagsExpressionMutationP620RPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_IDH2_p.K130del
Plasmid#82761PurposeGateway Donor vector containing IDH2, part of the Target Accelerator Plasmid Collection.DepositorInsertIDH2 (IDH2 Human)
UseGateway entry vectorTagsExpressionMutationK130delPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_DARC_p.W253R
Plasmid#82749PurposeGateway Donor vector containing DARC, part of the Target Accelerator Plasmid Collection.DepositorInsertACKR1 (ACKR1 Human)
UseGateway entry vectorTagsExpressionMutationW253R; S326FPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_DARC_p.T211S
Plasmid#82750PurposeGateway Donor vector containing DARC, part of the Target Accelerator Plasmid Collection.DepositorInsertACKR1 (ACKR1 Human)
UseGateway entry vectorTagsExpressionMutationT211S; S326FPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_AKT1_p.V201I
Plasmid#81453PurposeGateway Donor vector containing AKT1 , part of the Target Accelerator Plasmid Collection.DepositorInsertAKT1 (AKT1 Human)
UseGateway entry vectorTagsExpressionMutationV201I; p.117delEPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_AKT1_p.R370C
Plasmid#81416PurposeGateway Donor vector containing AKT1 , part of the Target Accelerator Plasmid Collection.DepositorInsertAKT1 (AKT1 Human)
UseGateway entry vectorTagsExpressionMutationR370C; p.114delEPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_CGREF1_WT_V5
Plasmid#82879PurposeGateway Donor vector containing CGREF1, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.DepositorInsertCGREF1 (CGREF1 Human)
UseGateway entry vectorTagsExpressionMutationPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_HRAS_p.A11D
Plasmid#81305PurposeGateway Donor vector containing HRAS , part of the Target Accelerator Plasmid Collection.DepositorInsertHRAS (HRAS Human)
UseGateway entry vectorTagsExpressionMutationA11DPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_HRAS_p.A59T
Plasmid#81292PurposeGateway Donor vector containing HRAS , part of the Target Accelerator Plasmid Collection.DepositorInsertHRAS (HRAS Human)
UseGateway entry vectorTagsExpressionMutationA59TPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_AKT3_p.E17K
Plasmid#82172PurposeGateway Donor vector containing AKT3 , part of the Target Accelerator Plasmid Collection.DepositorInsertAKT3 (AKT3 Human)
UseGateway entry vectorTagsExpressionMutationE17KPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_FTH1_p.A161T
Plasmid#81278PurposeGateway Donor vector containing FTH1 , part of the Target Accelerator Plasmid Collection.DepositorInsertFTH1 (FTH1 Human)
UseGateway entry vectorTagsExpressionMutationK88E, L98Q, A161TPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag DAK
Plasmid#20473DepositorInsertDAK (DAK Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pUCM-CLYBL-hNIL
Plasmid#105841PurposeDonor construct for introduction of hNIL factors to CLYBL safe harbor site and iPSC differentiation to motor neuronDepositorInsertsUseCRISPR and TALENTagsExpressionMutationPromoterCAG, EF-1alpha, and TRE3GAvailable sinceJuly 27, 2018AvailabilityAcademic Institutions and Nonprofits only -
pLEX305_FKBP12F36V-SHOC2
Plasmid#134522PurposeLentiviral plasmid expressing SHOC2 with N-term FKBP12(F36V) tagDepositorInsertSHOC2 (SHOC2 Human)
UseLentiviralTagsFKBP12F36V-2xHAExpressionMammalianMutationSilent mutations made at wobble base position at …PromoterhPGKAvailable sinceNov. 21, 2019AvailabilityAcademic Institutions and Nonprofits only -
pSBbi-Pur-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196078Purpose(Empty Backbone) Constitutive CRISPRi vector conferring puromycin resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
UseTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pSBtet-Pur-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196084Purpose(Empty Backbone) Inducible CRISPRi vector conferring puromycin resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
UseCRISPRTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pDONR223_HSD17B10_WT_V5
Plasmid#82941PurposeGateway Donor vector containing HSD17B10, used as an over expression control for gene expression analysis. Part of the Target Accelerator Plasmid Collection.DepositorInsertHSD17B10 (HSD17B10 Human)
UseGateway entry vectorTagsExpressionMutationPromoterNoneAvailable sinceApril 24, 2017AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag FGFR1
Plasmid#20486DepositorInsertFGFR1 (FGFR1 Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pSBtet-Hyg-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196082Purpose(Empty Backbone) Inducible CRISPRi vector conferring hygromycin B resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
Aminoglycoside phosphotransferase
UseCRISPRTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pSBbi-Hyg-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196076Purpose(Empty Backbone) Constitutive CRISPRi vector conferring hygromycin B resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
UseTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag GCK
Plasmid#20492DepositorInsertGCK (GCK Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pWZL Neo Myr Flag AKT3
Plasmid#20423DepositorInsertAKT3 (AKT3 Human)
UseRetroviralTagsFlag and MyrExpressionMammalianMutationPromoterAvailable sinceOct. 27, 2009AvailabilityAcademic Institutions and Nonprofits only -
pSBtet-Bla-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196080Purpose(Empty Backbone) Inducible CRISPRi vector conferring blasticidin S resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
Blasticidin S deaminase
UseCRISPRTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
pSBbi-Bla-dCas9-KRAB-MeCP2_hU6-SapI
Plasmid#196074Purpose(Empty Backbone) Constitutive CRISPRi vector conferring blasticidin S resistance, ready for insertion of gRNA targeting gene of interest using SapI restriction sites.DepositorInsertsdCas9-KRAB-MeCP2 repressor
hU6 promoter and gRNA scaffold
UseTagsExpressionMammalianMutationCatalytically dead mutant of the Cas9 endonucleas…PromoterAvailable sinceMarch 30, 2023AvailabilityAcademic Institutions and Nonprofits only -
KRD22_HBA1(HBA1reg-HBB-longHAs)
Plasmid#232403PurposeAAV production plasmid for HBA1 long HAs vector from Figs. 3-6 that mediates HDR at HBA1 locus using HBA1 sg5 gRNA. HBB gene includes introns; HBA1 UTRs flank full HBA1-2A-YFP cassette. HAs are ~900bpDepositorUseTagsExpressionMammalianMutationPromoterAvailable sinceApril 18, 2025AvailabilityAcademic Institutions and Nonprofits only -
CLYBL-(Ef1a-SBP-LNGFR-T2A-mApple)-(CAG-rtTA)-(TRE-hNIL))
Plasmid#105842PurposeDonor construct for introduction of hNIL factors and SBP-LNGFR for streptavidin bead enrichmentDepositorInsertsUseCRISPR and TALENTagsExpressionMutationPromoterCAG, EF-1alpha, and TRE3GAvailable sinceApril 13, 2018AvailabilityAcademic Institutions and Nonprofits only -
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EC71174
Plasmid#154067PurposeLevel 2 Golden Gate vector, pL2M-HvHSP17-CREU5-UBQ-loxmCHERRYER-eGFPERDepositorInsertsHS Cre recombinase
Ubiquitin promoter driving mCherry with the 35S terminator, flanked by lox sites, followed by eGFP with the Actin terminator
HYGROMYCIN Resistance Cassette
UseCre/Lox and Synthetic Biology; Golden gateTagsExpressionBacterial and PlantMutationThe Arabidopsis thaliana U5 small nuclear ribonuc…Promoter35S promoter, Hordeum vulgare HSP 17 promoter use…Available sinceSept. 29, 2020AvailabilityAcademic Institutions and Nonprofits only -
SHP2(WT)@pLKO-Trex-SBP
Plasmid#85457PurposeGene expressionDepositorInsertSHP2 (PTPN11 Human)
UseLentiviralTagsSBP TagExpressionMammalianMutationPromoterRSVAvailable sinceFeb. 6, 2017AvailabilityAcademic Institutions and Nonprofits only -
SHP2(C459S)@pLKO-Trex-HA
Plasmid#85459PurposeExpresses SHP2 mutant in mammalian cellsDepositorInsertSHP2 (PTPN11 Human)
UseLentiviralTagsHAExpressionMammalianMutationC459SPromoterRSVAvailable sinceFeb. 6, 2017AvailabilityAcademic Institutions and Nonprofits only -
SHP2(T253M/Q257L)@pLKO-Trex-SBP
Plasmid#85458PurposeSHP2 mutant gene expressionDepositorInsertSHP2 (PTPN11 Human)
UseLentiviralTagsSBP TagExpressionMammalianMutationT253M/Q257LPromoterRSVAvailable sinceFeb. 6, 2017AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_WDR38:1-314
Plasmid#211329PurposeMammalian expression of full-length human WDR38. C-terminal HiBiT tag.DepositorInsertWDR38:M1-T314 (WDR38 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_RBBP7:1-425
Plasmid#211113PurposeMammalian expression of full-length human RBBP7. N-terminal HiBiT tag.DepositorInsertRBBP7:M1-S425 (RBBP7 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pLV-hUbC-GBX2-CDX124-Cas9-T2A-GFP
Plasmid#192287PurposeExpresses Cas9-T2A-GFP and four sgRNAs: GBX2, CDX1, CDX2, CDX4DepositorInsertUseCRISPR and LentiviralTagsExpressionMammalianMutationPromoterAvailable sinceDec. 6, 2023AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR20:1-569
Plasmid#211136PurposeMammalian expression of full-length human WDR20. N-terminal HiBiT tag.DepositorInsertWDR20:M1-P569 (WDR20 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_DNAAF10:1-357
Plasmid#211138PurposeMammalian expression of full-length human DNAAF10. N-terminal HiBiT tag.DepositorInsertDNAAF10:M1-I357 (WDR92 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_PPWD1:1-646
Plasmid#211116PurposeMammalian expression of full-length human PPWD1. N-terminal HiBiT tag.DepositorInsertPPWD1:M1-K646 (PPWD1 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR70:1-654
Plasmid#211143PurposeMammalian expression of full-length human WDR70. N-terminal HiBiT tag.DepositorInsertWDR70:M1-I654 (WDR70 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_WDR70:1-654
Plasmid#211184PurposeMammalian expression of full-length human WDR70. C-terminal HiBiT tag.DepositorInsertWDR70:M1-I654 (WDR70 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_WDR20:1-569
Plasmid#211177PurposeMammalian expression of full-length human WDR20. C-terminal HiBiT tag.DepositorInsertWDR20:M1-P569 (WDR20 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_DNAAF10:1-357
Plasmid#211179PurposeMammalian expression of full-length human DNAAF10. C-terminal HiBiT tag.DepositorInsertDNAAF10:M1-I357 (WDR92 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_PPWD1:1-646
Plasmid#211157PurposeMammalian expression of full-length human PPWD1. C-terminal HiBiT tag.DepositorInsertPPWD1:M1-K646 (PPWD1 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_RBBP7:1-425
Plasmid#211152PurposeMammalian expression of full-length human RBBP7. C-terminal HiBiT tag.DepositorInsertRBBP7:M1-S425 (RBBP7 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceMarch 19, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-C_WDR25:1-544
Plasmid#211325PurposeMammalian expression of full-length human WDR25. C-terminal HiBiT tag.DepositorInsertWDR25:M1-H544 (WDR25 Human)
UseTagsGSSGGSSGVSGWRLFKKISExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR86:1-376
Plasmid#211260PurposeMammalian expression of full-length human WDR86. N-terminal HiBiT tag.DepositorInsertWDR86:M1-A376 (WDR86 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR38:1-314
Plasmid#211255PurposeMammalian expression of full-length human WDR38. N-terminal HiBiT tag.DepositorInsertWDR38:M1-T314 (WDR38 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR53:1-358
Plasmid#211256PurposeMammalian expression of full-length human WDR53. N-terminal HiBiT tag.DepositorInsertWDR53:M1-F358 (WDR53 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only -
pBiT3.1-N_WDR25:1-544
Plasmid#211251PurposeMammalian expression of full-length human WDR25. N-terminal HiBiT tag.DepositorInsertWDR25:M1-H544 (WDR25 Human)
UseTagsMVSGWRLFKKISGSSGGSSGExpressionMammalianMutationwild typePromoterCMVAvailable sinceFeb. 21, 2024AvailabilityAcademic Institutions and Nonprofits only