We narrowed to 82 results for: LIS

Showing: 1 - 20 of 82 results

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Lenti-human-TF-gRNA-puromycin

Pooled Library

#162275

Purpose

Knockout library targeting a set of human transcription factors for loss-of-function screening.

Depositor

Chunliang Li

Article

Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

Species

Homo sapiens

Use

Lentiviral

Available Since

Dec. 15, 2020

Availability

Academic Institutions and Nonprofits only
Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

Pooled Library

#171531

Purpose

Knockout library targeting ubiquitination and de-ubiquitination complex genes.

Depositor

Chunliang Li

Article

Wright et al Proc Natl Acad Sci U S A. 2023 Apr 18;12

Expression

Mammalian

Species

Homo sapiens

Use

Lentiviral

Available Since

June 22, 2021

Availability

Academic Institutions and Nonprofits only
Mouse Metabolism Library

Pooled Library

#163966

Purpose

Knockout library targeting mouse metabolic genes.

Depositor

Alec Kimmelman

Article

Biancur et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Use

CRISPR and Lentiviral

Available Since

July 1, 2021

Availability

Academic Institutions and Nonprofits only
Mouse metabolism knockout library

Pooled Library

#160129

Purpose

Targets mouse metabolic genes and includes most metabolic enzymes and transporters.

Depositor

Kivanc Birsoy

Article

Zhu et al Cell Metab. 2020 Oct 28. pii: S1550-4131

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Nov. 10, 2020

Availability

Academic Institutions and Nonprofits only
Mouse lipid metabolism knockout library

Pooled Library

#206248

Purpose

The lipid metabolism library contains guide RNAs against 295 genes targeting mouse genes encoding enzymes that directly impact lipid metabolism.

Depositor

Kivanc Birsoy

Article

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Use

CRISPR and Lentiviral

Available Since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only
Human Lipid Droplet and Metabolism Library

Pooled Library

#191535

Purpose

Targets 1,196 genes related to lipid droplet biology and cell metabolism.

Depositor

James Olzmann

Article

Roberts et al Dev Cell. 2023 Jul 18:S1534-5807(23)0033

Expression

Mammalian

Use

CRISPR and Lentiviral

Available Since

March 1, 2023

Availability

Academic Institutions and Nonprofits only
Mouse sphingolipid metabolism knockout library

Pooled Library

#206249

Purpose

The sphingolipid metabolism library targets 82 mouse genes in the de novo ceramide and downstream sphingolipid metabolism pathways.

Depositor

Kivanc Birsoy

Article

Soula et al Nature. 2024 Aug 7. doi: 10.1038/s41586-

Use

CRISPR and Lentiviral

Available Since

Aug. 29, 2024

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library A

Pooled Library

#174196

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
Liu Lab MusCK Library B

Pooled Library

#174197

Purpose

MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

Depositor

Xiaole Shirley Liu

Article

Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

Expression

Mammalian

Species

Mus musculus

Use

CRISPR and Lentiviral

Available Since

Oct. 29, 2021

Availability

Academic Institutions and Nonprofits only
pUC57kan-T7-mt-gRNA library

Pooled Library

#82480

Purpose

This library is intended to be used as a technical tool for removal of mitochondrial DNA from mouse genomic DNA preparations.

Depositor

Wei Xie

Article

Wu et al Nature. 2016 Jun 30;534(7609):652-7.

Available Since

April 5, 2017

Availability

Academic Institutions and Nonprofits only
Human genome-wide lentiviral CRISPR gRNA library version 1

Pooled Library

#67989

Purpose

Knockout library targeting 18,010 human genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
Mouse genome-wide lentiviral CRISPR gRNA library version 2

Pooled Library

#67988

Purpose

Knockout library targeting 18,424 mouse genes. gRNAs were improved using a new design pipeline and improved gRNA scaffold.

Depositor

Kosuke Yusa

Article

Tzelepis et al Cell Rep. 2016 Oct 18;17(4):1193-1205. d

Species

Homo sapiens, Mus musculus, and Synthetic

Use

CRISPR and Lentiviral

Available Since

Oct. 14, 2016

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_2

Pooled Library

#134583

Purpose

Targets Drosophila orthologs of vertebrate genes that have undergone expansion in the vertebrate line

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available Since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_1

Pooled Library

#134582

Purpose

Targets kinases, phosphatases, and Drosophila orthologs of drug targets

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available Since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
Drosophila_sgRNA_group_3

Pooled Library

#134584

Purpose

Targets all other Drosophila genes not included in Groups 1 and 2

Depositor

Norbert Perrimon

Article

Viswanatha et al Elife. 2018 Jul 27;7. pii: 36333. doi: 1

Expression

Insect

Species

Drosophila melanogaster

Use

CRISPR

Available Since

Feb. 25, 2020

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-mBC backbone (p025)

Pooled Library

#194097

Purpose

pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #2 (low: no promoter, p029)

Pooled Library

#217421

Purpose

scQers promoter control #2 (low: no promoter, p029)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
pre-associated oBC-minP-GFP-mBC backbone (p043)

Pooled Library

#194098

Purpose

pre-associated oBC-minP-GFP-mBC backbone (p043), can directly be used to deposit library of regulatory elements

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #1 (low: minimal promoter, p027)

Pooled Library

#217420

Purpose

scQers promoter control #1 (low: minimal promoter, p027)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only
scQers promoter control #5 (high: EEF1A1 promoter, p028)

Pooled Library

#217424

Purpose

scQers promoter control #5 (high: EEF1A1 promoter, p028)

Depositor

Jay Shendure

Article

Lalanne et al bioRxiv 2022.12.10.519236

Expression

Bacterial and Mammalian

Use

RNAi

Available Since

April 3, 2024

Availability

Academic Institutions and Nonprofits only

Showing: 1 - 20 of 82 results

Results per page:

Sort results by:

More Filters

We narrowed to 82 results for: LIS

Lenti-human-TF-gRNA-puromycin

Lenti-human-UBDUB-gRNA-puromycin-IRES-CFP

Mouse Metabolism Library

Mouse metabolism knockout library

Mouse lipid metabolism knockout library

Human Lipid Droplet and Metabolism Library

Mouse sphingolipid metabolism knockout library

Liu Lab MusCK Library A

Liu Lab MusCK Library B

pUC57kan-T7-mt-gRNA library

Human genome-wide lentiviral CRISPR gRNA library version 1

Mouse genome-wide lentiviral CRISPR gRNA library version 2

Drosophila_sgRNA_group_2

Drosophila_sgRNA_group_1

Drosophila_sgRNA_group_3

pre-associated oBC-mBC backbone (p025)

scQers promoter control #2 (low: no promoter, p029)

pre-associated oBC-minP-GFP-mBC backbone (p043)

scQers promoter control #1 (low: minimal promoter, p027)

scQers promoter control #5 (high: EEF1A1 promoter, p028)

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