We narrowed to 117 results for: son

1. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available Since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

2. Human CRISPR Poison Exon Knockout Library

   Pooled Library

   #138084

   Purpose

   The human pgPoison library induces skipping of “poison” cassette exons and corresponding upstream constitutive exons by targeting 3' splice sites with paired gRNAs (pgRNAs).

   Depositor

   Robert Bradley

   Article

   Thomas et al Nat Genet. 2020 Jan;52(1):84-94. doi: 10

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   March 6, 2020

   Availability

   Academic Institutions and Nonprofits only

3. SPLINTR mCHERRY v1

   Pooled Library

   #179775

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

4. SPLINTR GFP v1

   Pooled Library

   #179774

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

5. SPLINTR BFP v1

   Pooled Library

   #179776

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

6. Self-targeting epegRNA library, +5 G>H (lDS004)

   Pooled Library

   #227707

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

7. StopPR epegRNA library (lAC002)

   Pooled Library

   #227706

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

8. Self-targeting epegRNA library, Tiled edits (lRM001)

   Pooled Library

   #227708

   Purpose

   CRISPR guide RNA library for prime editing

   Depositor

   Brittany Adamson

   Article

   Cirincione et al Nat Methods. 2024 Nov 19. doi: 10.1038/s

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   Jan. 23, 2025

   Availability

   Academic Institutions and Nonprofits only

9. DNA repair library with 1,573 sgRNAs

   Pooled Library

   #177663

   Purpose

   CRISPR-interference (CRISPRi) library of 1,573 sgRNAs targeting 476 genes encoding factors involved in DNA repair and associated processes

   Depositor

   Brittany Adamson

   Article

   Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

   Species

   Homo sapiens

   Use

   CRISPR

   Available Since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

10. DNA repair library with 336 sgRNAs

    Pooled Library

    #177664

    Purpose

    CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available Since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

11. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209734

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

12. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209735

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Validation (mVAL) CRISPR Library

    Pooled Library

    #159391

    Purpose

    Pooled CRISPR library targets core intrinsic immune evasion genes

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

14. Mouse Toronto KnockOut (mTKO) CRISPR Library - pLCKO2

    Pooled Library

    #159393

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only

15. Mouse messenger-RBP sgRNA library

    Pooled Library

    #169082

    Purpose

    CRISPR library targeting mouse genes

    Depositor

    Martin Turner

    Article

    Turner et al eLife. 2022 Apr 22;11. pii: 72313. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Sept. 10, 2021

    Availability

    Academic Institutions and Nonprofits only

16. CRASP-Seq Gene KO v1 empty

    Pooled Library

    #232069

    Purpose

    Flexible CRASP-Seq platform for studying splicing regulation. Used to study how protein coding genes impact splicing of minigene reporters.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

17. CRASP-Seq CBC Backbone

    Pooled Library

    #232068

    Purpose

    The CRASP-Seq backbone is designed to accommodate the cloning of diverse gRNA libraries. It includes a cell barcode (CBC), which enhances its functionality by enabling library preparation.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

18. CRASP-Seq BE Tiling v1 empty

    Pooled Library

    #232070

    Purpose

    Tiling guides designed to target 39 splicing-related genes, along with several thousand control gRNAs. Optimized for CRASP-Seq experiments combined with high-throughput base editing mutagenesis.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Behera et al bioRxiv [Preprint]. 2025 Apr 26:2025.04.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available Since

    Oct. 28, 2025

    Availability

    Academic Institutions and Nonprofits only

19. CHyMErA Large-Scale Exon Deletion hgRNA Library

    Pooled Library

    #209736

    Purpose

    CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available Since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

20. Mouse Toronto KnockOut (mTKO) CRISPR Library - lentiCRISPRv2

    Pooled Library

    #159392

    Purpose

    Mouse lentiviral genome-wide CRISPR library

    Depositor

    Jason Moffat

    Article

    Lawson et al Nature. 2020 Oct;586(7827):120-126. doi:

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available Since

    Nov. 9, 2020

    Availability

    Academic Institutions and Nonprofits only