We narrowed to 280 results for: CIL

1. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

2. CHyMErA Paralog&Dual-targeting hgRNA Library

   Pooled Library

   #155199

   Purpose

   Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

   Depositor

   Benjamin Blencowe, Jason Moffat

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

3. Human SLC KO Library

   Pooled Library

   #132552

   Purpose

   Expresses gRNAs for knockout of the human Solute Carrier family

   Depositor

   Giulio Superti-Furga

   Article

   Girardi et al Nat Chem Biol. 2020 Apr;16(4):469-478. d

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   May 7, 2020

   Availability

   Academic Institutions and Nonprofits only

4. Murine cell surface protein knockout (McspKO) library

   Pooled Library

   #200445

   Purpose

   A CRISPR library targeting 1,157 cell surface genes and 98 control genes with four sgRNAs per gene

   Depositor

   Junjie Chen

   Article

   Wang et al Proc Natl Acad Sci U S A. 2022 Jun 21;11

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR, Lentiviral, and Mouse Targeting

   Available since

   Oct. 26, 2023

   Availability

   Academic Institutions and Nonprofits only

5. Bison sgRNA library

   Pooled Library

   #169942

   Purpose

   The BISON CRISPR library targets 713 E1, E2, and E3 ubiquitin ligases, deubiquitinases, and control genes and contains 2,852 guide RNAs. It was cloned into the pXPR003.

   Depositor

   Benjamin Ebert

   Article

   Slabicki et al Nature. 2020 Sep;585(7824):293-297. doi:

   Use

   Lentiviral

   Available since

   Sept. 9, 2021

   Availability

   Academic Institutions and Nonprofits only

6. Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases

   Pooled Library

   #101927

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Drug targets, kinases, phosphatases. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

7. Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility

   Pooled Library

   #101931

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Trafficking, mitochondrial, motility. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

8. TP53 MITE Library

   Pooled Library

   #113569

   Purpose

   Pooled lentiviral plasmid library containing ~8,000 single amino acid substitution and nonsense mutant variants of p53

   Depositor

   William Hahn, David Root

   Article

   Giacomelli et al Nat Genet. 2018 Oct;50(10):1381-1387. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Jan. 4, 2019

   Availability

   Academic Institutions and Nonprofits only

9. MYC-CRISPR

   Pooled Library

   #173195

   Purpose

   This pooled lentiviral CRISPR knockout library targets E-boxes genome-wide and can be applied for identification of essential MYC binding sites in a wide range of human cells.

   Depositor

   Agnieszka Dzikiewicz-Krawczyk

   Article

   Kazimierska et al Mol Oncol. 2023 Nov;17(11):2295-2313. do

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available since

   Aug. 11, 2021

   Availability

   Academic Institutions and Nonprofits only

10. pSADB19-dTomato Barcode Library

    Pooled Library

    #227671

    Purpose

    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of SADB19 strain G-deleted rabies virus.

    Depositor

    Tomasz Nowakowski, Cathryn Cadwell

    Article

    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

    Expression

    Mammalian

    Species

    Synthetic

    Available since

    Feb. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

11. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209734

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

12. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209735

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

13. Mouse Chromatin Regulator Library

    Pooled Library

    #200011

    Purpose

    CRISPR KO library targeting a comprehensive set of genes with annotated function as chromatin regulators.

    Depositor

    Gabriel Griffin, Robert Manguso, Bradley Bernstein

    Article

    Griffin et al Nature. 2021 Jul;595(7866):309-314. doi:

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Dec. 15, 2023

    Availability

    Academic Institutions and Nonprofits only

14. pLCKO2::TKOv3

    Pooled Library

    #125517

    Purpose

    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

    Depositor

    Jason Moffat

    Article

    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

15. Liu Lab MusCK Library A

    Pooled Library

    #174196

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK A contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

16. Human Base Editing Sensor Library

    Pooled Library

    #179218

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

17. Mouse Base Editing Sensor Library

    Pooled Library

    #179217

    Purpose

    sgRNAs that target frequently occurring cancer associated mutations identified in the MSK IMPACT dataset that can be modeled with cytosine base editing.

    Depositor

    Lukas Dow

    Article

    Sanchez-Rivera et al Nat Biotechnol. 2022 Feb 14. pii: 10.103

    Expression

    Mammalian

    Use

    Lentiviral

    Available since

    June 16, 2022

    Availability

    Academic Institutions and Nonprofits only

18. pCVSN2c-MCP-oScarlet-KASH-6xMS2 Barcode Library

    Pooled Library

    #227672

    Purpose

    RVdG genome plasmids that carry an error-correctable barcode compatible with 3’ capture single cell or single nuclei RNA sequencing readout. For the production of CVS N2c strain G-deleted rabies virus

    Depositor

    Tomasz Nowakowski, Cathryn Cadwell

    Article

    Shin et al bioRxiv [Preprint]. 2024 Dec 11:2024.10.

    Expression

    Mammalian

    Species

    Synthetic

    Available since

    Feb. 12, 2025

    Availability

    Academic Institutions and Nonprofits only

19. Liu Lab MusCK Library B

    Pooled Library

    #174197

    Purpose

    MusCK library contains 23,622 unique sgRNAs targeting 4,787 gene locations in the genome. Sub-library MusCK M_b contains 5 gRNAs per gene.

    Depositor

    Xiaole Shirley Liu

    Article

    Wang et al Cell. 2021 Oct 14;184(21):5357-5374.e22.

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR and Lentiviral

    Available since

    Oct. 29, 2021

    Availability

    Academic Institutions and Nonprofits only

20. CHyMErA Large-Scale Exon Deletion hgRNA Library

    Pooled Library

    #209736

    Purpose

    CHyMErA Exon Deletion hgRNA Library allows identification of frame-preserving exons that affect cell fitness in human cells using the CHyMErA screening platform.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only