374 results

1. scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Pooled Library

   #217423

   Purpose

   scQers promoter control #4 (intermediate: Pgk1 promoter, p042)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

2. scQers promoter control #1 (low: minimal promoter, p027)

   Pooled Library

   #217420

   Purpose

   scQers promoter control #1 (low: minimal promoter, p027)

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

3. pre-associated oBC-mBC backbone (p025)

   Pooled Library

   #194097

   Purpose

   pre-associated oBC-mBC backbone (p025), can insert additional reporter constructs

   Depositor

   Jay Shendure

   Article

   Lalanne et al bioRxiv 2022.12.10.519236

   Expression

   Bacterial and Mammalian

   Use

   RNAi

   Available since

   April 3, 2024

   Availability

   Academic Institutions and Nonprofits only

4. plIG-106_NY-ESO-1_TCR_SR_Library

   Pooled Library

   #207474

   Purpose

   NY-ESO-1 TCR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

5. plIG-107_NY-ESO-1_TCR_TF_Library

   Pooled Library

   #207475

   Purpose

   NY-ESO-1 TCR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

6. plIG-109_CD19-BBz_CAR_SR_Library

   Pooled Library

   #207476

   Purpose

   CD19-BBz CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cells

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

7. plIG-110_CD19-BBz_CAR_TF_Library

   Pooled Library

   #207477

   Purpose

   CD19-BBz CAR in combination with 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

8. plIG-124_HA-GD2-28z_CAR_SR_Library

   Pooled Library

   #207479

   Purpose

   HA-GD2-28z CAR in combination with 129 surface receptors and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knockin (ModPoKI) into the TRAC locus of human T cel

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

9. plIG-132_CD19-28z_CAR_TF_and_SR_Library

   Pooled Library

   #207481

   Purpose

   CD19-28z CAR in combination with 129 surface receptors, 100 transcription factors (and related proteins) and 2 controls (GFP/RFP). Library can be used to generate HDR templates for modular pooled knoc

   Depositor

   Alexander Marson

   Article

   Blaeschke et al Cell. 2023 Sep 14;186(19):4216-4234.e33.

   Species

   Homo sapiens

   Use

   CRISPR

   Available since

   Jan. 26, 2024

   Availability

   Academic Institutions and Nonprofits only

10. DNA repair library with 336 sgRNAs

    Pooled Library

    #177664

    Purpose

    CRISPR-interference (CRISPRi) library of 366 sgRNAs targeting 118 genes encoding factors involved in DNA repair and associated processes

    Depositor

    Brittany Adamson

    Article

    Hussmann et al Cell. 2021 Oct 28;184(22):5653-5669.e25.

    Species

    Homo sapiens

    Use

    CRISPR

    Available since

    Nov. 29, 2023

    Availability

    Academic Institutions and Nonprofits only

11. TRE-MPRA_minTK Library

    Pooled Library

    #201014

    Purpose

    Massively parallel reporter assay (MPRA) library with minTK promoter

    Depositor

    Justin English

    Article

    Zahm et al bioRxiv. 2023 May 11:2023.05.11.539703.

    Expression

    Mammalian

    Use

    Luciferase

    Available since

    Oct. 31, 2023

    Availability

    Academic Institutions and Nonprofits only

12. SARS-CoV-2 RBD BQ.1.1 SSM Library

    Pooled Library

    #1000000231

    Depositor

    Tyler Starr

    Available since

    Oct. 25, 2023

    Availability

    Academic Institutions and Nonprofits only

13. mU6-CR1-CRISPRiv2_hU6-CR3-NT-ctrl-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197348

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed non-targeting control guide.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

14. mU6-CR1-CRISPRiv2_hU6-CR3-EMC2-guide_EF1a-PuroR-T2A-BFP

    Pooled Library

    #197349

    Purpose

    To allow for genome-wide genetic modifier screening, the library has a second fixed guide targeting EMC2.

    Depositor

    Jonathan Weissman, Rebecca Voorhees

    Article

    Guna et al BMC Genomics. 2023 Oct 30;24(1):651. doi

    Species

    Homo sapiens

    Use

    Lentiviral

    Available since

    May 25, 2023

    Availability

    Academic Institutions and Nonprofits only

15. iSPI_pSer_Subpool#1

    Pooled Library

    #188526

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

16. iSPI_pSer_Subpool#3

    Pooled Library

    #188528

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

17. iSPI_pSer_Subpool#4

    Pooled Library

    #188529

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

18. iSPI_pSer_Subpool#5

    Pooled Library

    #188530

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

19. iSPI_pSer_Subpool#6

    Pooled Library

    #188531

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only

20. iSPI_pSer_Subpool#7

    Pooled Library

    #188532

    Purpose

    Express a library of MBP-Fusion proteins containing phosphoserine at a defined position in the fusion protein

    Depositor

    Jesse Rinehart

    Article

    Gassaway et al Nat Methods. 2022 Oct 24. pii: 10.1038/s

    Expression

    Bacterial

    Species

    Homo sapiens

    Available since

    Dec. 14, 2022

    Availability

    Academic Institutions and Nonprofits only