386 results

1. mCRISPRi-v2, genome-wide, 10 sgRNAs/gene

   Pooled Library

   #1000000092

   Purpose

   Genome-wide CRISPR gRNA pooled library for inhibition of mouse genes

   Depositor

   Jonathan Weissman

   Available Since

   Nov. 15, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1

   Pooled Library

   #101932

   Purpose

   Bassik lab Human CRISPR-Cas9 Deletion Library - Unassigned1. Coexpresses mCherry.

   Depositor

   Michael Bassik

   Article

   Morgens et al Nat Commun. 2017 May 5;8:15178. doi: 10.

   Expression

   Mammalian

   Use

   CRISPR

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

3. Human Lentiviral sgRNA Library - Cell Cycle

   Pooled Library

   #51046

   Purpose

   Sub-pool of Sabatini/Lander sgRNA library enriched for cell cycle-related targets.

   Depositor

   Eric Lander, David Sabatini

   Article

   Wang et al Science. 2014 Jan 3;343(6166):80-4. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 7, 2014

   Availability

   Academic Institutions and Nonprofits only

4. Mouse sgRNA library Gouda in pRDA_118 backbone

   Pooled Library

   #136987

   Purpose

   Expresses sgRNAs targeting mouse genes

   Depositor

   John Doench

   Article

   DeWeirdt et al Nat Commun. 2020 Feb 6;11(1):752. doi: 1

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 24, 2020

   Availability

   Academic Institutions and Nonprofits only

5. Human CRISPR lncRNA activation library (SAM) in lenti sgRNA(MS2)_zeo backbone

   Pooled Library

   #1000000106

   Purpose

   Human CRISPR Synergistic Activation Mediator (SAM) pooled library for the transcriptional activation of lncRNAs

   Depositor

   Feng Zhang

   Available Since

   June 5, 2017

   Availability

   Academic Institutions and Nonprofits only

6. DNA repair library with 1,513 sgRNAs

   Pooled Library

   #177670

   Purpose

   CRISPR-interference (CRISPRi) library designed to target 476 genes involved in DNA repair and associated processes. It contains 1,513 sgRNAs and 60 non-targeting control sgRNAs.

   Depositor

   Brittany Adamson

   Article

   Chen et al Cell. 2021 Oct 28;184(22):5635-5652.e29.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   July 11, 2023

   Availability

   Academic Institutions and Nonprofits only

7. SPLINTR BFP v1

   Pooled Library

   #179776

   Purpose

   SPLINTR (Single-cell Profiling and LINeage TRacing) is a high diversity lentiviral barcode library for tracing clonal lineages using bulk and single-cell readouts.

   Depositor

   Mark Dawson

   Article

   Fennell et al Nature. 2022 Jan;601(7891):125-131. doi:

   Expression

   Mammalian

   Use

   Lentiviral

   Available Since

   May 11, 2022

   Availability

   Academic Institutions and Nonprofits only

8. Bassik lab Mouse CRISPR-Cas9 Deletion Library - Apoptosis and cancer

   Pooled Library

   #1000000121

   Purpose

   CRISPR gRNA mouse knockout pooled library - Apoptosis and cancer

   Depositor

   Michael Bassik

   Available Since

   May 23, 2018

   Availability

   Academic Institutions and Nonprofits only

9. Human Genome-Wide Reduced Double-gRNA library

   Pooled Library

   #137999

   Purpose

   This gRNA library targets the human coding genome, aimed to reduce the scale of genome-wide perturbation screens up to fivefold compared to conventional methods, without sacrificing performance.

   Depositor

   Leopold Parts

   Article

   Peets et al bioRxiv 859652

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

10. hCRISPRi-v2, Mitochondria, Trafficking, and Motility (h4), top 5 sgRNAs/gene

    Pooled Library

    #83974

    Purpose

    Human CRISPRi Pooled Library targeting Mitochondria, Trafficking, and Motility genes

    Depositor

    Jonathan Weissman

    Article

    Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

    Available Since

    Dec. 14, 2016

    Availability

    Academic Institutions and Nonprofits only