We narrowed to 71 results for: CRISPR-Cas9

1. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

2. Human sgRNA library Brunello in lentiGuide-Puro

   Pooled Library

   #73178

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 19,114 genes and containing 76,441 unique sgRNAs along with 1000 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Feb. 9, 2016

   Availability

   Academic Institutions and Nonprofits only

3. UMI-sgRNA-TF

   Pooled Library

   #234819

   Purpose

   Unique molecular identifiers-linked sgRNA library targeting transcription factors (TFs) in mice.

   Depositor

   Benjamin Ebert

   Article

   Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

4. UMI-sgRNA-CH

   Pooled Library

   #234820

   Purpose

   Unique molecular identifiers-linked sgRNA library targeting chromatin factors (CH) in mice.

   Depositor

   Benjamin Ebert

   Article

   Loke et al Blood. 2025 Jun 10:blood.2024028033. doi

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   June 11, 2025

   Availability

   Academic Institutions and Nonprofits only

5. Lenti-human-TF-gRNA-puromycin

   Pooled Library

   #162275

   Purpose

   This is a gRNA library targeting on ~1600 human transcription factors for genetic screening.

   Depositor

   Chunliang Li

   Article

   Zhang et al Elife. 2020 Oct 1;9. pii: 57858. doi: 10

   Species

   Homo sapiens

   Use

   Lentiviral

   Available since

   Dec. 15, 2020

   Availability

   Academic Institutions and Nonprofits only

6. Mouse Brie kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75316

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro targeting 713 kinase genes and containing 2,852 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

7. Human Brunello kinome pooled library, guides 1-4 in lentiGuide-Puro backbone

   Pooled Library

   #75312

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

8. Human Brunello kinome pooled library, guides 5-8 in lentiGuide-Puro backbone

   Pooled Library

   #75313

   Purpose

   Human sgRNA library in backbone lentiGuide-Puro targeting 763 kinase genes and containing 3,052 unique sgRNAs along with 100 non-targeting controls

   Depositor

   John Doench, David Root

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   June 27, 2016

   Availability

   Academic Institutions and Nonprofits only

9. CHyMErA Exon-deletion hgRNA Library

   Pooled Library

   #155200

   Purpose

   Hybrid guide RNA library targeting human alternative cassette exons for deletion and disruption

   Depositor

   Jason Moffat, Benjamin Blencowe

   Article

   Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available since

   Sept. 2, 2020

   Availability

   Academic Institutions and Nonprofits only

10. CHyMErA Paralog&Dual-targeting hgRNA Library

    Pooled Library

    #155199

    Purpose

    Hybrid guide RNA library targetings human paralog pairs and other protein-coding genes.

    Depositor

    Jason Moffat, Benjamin Blencowe

    Article

    Gonatopoulos-Pournatzis et al Nat Biotechnol. 2020 May;38(5):638-648.

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 2, 2020

    Availability

    Academic Institutions and Nonprofits only

11. p11-3’_8xN_PAM-site1 (RTW554)

    Pooled Library

    #160132

    Purpose

    Plasmid library harboring a randomized 8nt PAM 3’ of target site 1. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

12. p11-3’_8xN_PAM-site2 (RTW555)

    Pooled Library

    #160133

    Purpose

    Plasmid library harboring a randomized 8nt PAM 3’ of target site 2. Can be used to profile CRISPR-Cas PAM requirements of enzymes that recognize 3’ PAMs (e.g. Cas9)

    Depositor

    Keith Joung, Benjamin Kleinstiver

    Article

    Walton et al Nat Protoc. 2021 Feb 5. pii: 10.1038/s41

    Species

    Synthetic

    Use

    CRISPR

    Available since

    Feb. 8, 2021

    Availability

    Academic Institutions and Nonprofits only

13. Human Transporter Knockout library

    Pooled Library

    #213695

    Purpose

    Next generation transporter-focused CRISPR/Cas9 library targeting transmembrane transporters to test the impact of transporters on biological processes.

    Depositor

    RESOLUTE Consortium, Giulio Superti-Furga

    Article

    Ferdigg et al Life Sci Alliance. 2024 Nov 22;8(2):e202

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Sept. 13, 2024

    Availability

    Academic Institutions and Nonprofits only

14. lentiGuide-Puro-pKO-library

    Pooled Library

    #190744

    Purpose

    CRISPR/Cas9 paired-guide RNA library to delete proximal poly(A) sites in mouse melanoma.

    Depositor

    Robert Bradley

    Article

    Gabel et al Nat Commun. 2024 Feb 1;15(1):959. doi: 1

    Expression

    Mammalian

    Species

    Mus musculus

    Use

    CRISPR, Lentiviral, and Mouse Targeting

    Available since

    Feb. 2, 2024

    Availability

    Academic Institutions and Nonprofits only

15. psgRNA_EcoWG1

    Pooled Library

    #131625

    Purpose

    Improved genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Calvo-Villamanan et al Nucleic Acids Res. 2020 Apr 30. pii: 582

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available since

    May 12, 2020

    Availability

    Academic Institutions and Nonprofits only

16. pLCKO2::TKOv3

    Pooled Library

    #125517

    Purpose

    Human CRISPR lentiviral library containing 70,948 guides (4-5 guides/gene) targeting 18,053 human protein-coding genes, in a non-Cas9 containing backbone

    Depositor

    Jason Moffat

    Article

    Mair et al Cell Rep. 2019 Apr 9;27(2):599-615.e12.

    Expression

    Mammalian

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 1, 2019

    Availability

    Academic Institutions and Nonprofits only

17. KSHV Tiling Library

    Pooled Library

    #180272

    Purpose

    sgRNA library tiling entire ~154 kb of the BAC16 Kaposi’s Sarcoma-associated Herpes viral genome. A guide every ~8 bp allows pooled screening of viral genome.

    Depositor

    Britt Glaunsinger

    Article

    Morgens et al PLoS Pathog. 2022 Jan 18;18(1):e1010236.

    Expression

    Mammalian

    Species

    Kaposi’s sarcoma-associated herpes virus

    Use

    Lentiviral

    Available since

    Feb. 11, 2022

    Availability

    Academic Institutions and Nonprofits only

18. psgRNA Library

    Pooled Library

    #115927

    Purpose

    Genome-wide knockdown of E. coli genes

    Depositor

    David Bikard

    Article

    Cui et al Nat Commun. 2018 May 15;9(1):1912. doi:

    Expression

    Bacterial

    Species

    Escherichia coli

    Use

    CRISPR

    Available since

    June 6, 2019

    Availability

    Academic Institutions and Nonprofits only

19. CHyMErA LbCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209734

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different LbCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

20. CHyMErA AsCas12a Nuclease Optimization hgRNA Library

    Pooled Library

    #209735

    Purpose

    CHyMErA Cas12a Nuclease Optimization hgRNA Libraries allows assessment and comparison of the efficacy of different AsCas12a nucleases in the context of the Cas9-Cas12a CHyMErA system.

    Depositor

    Thomas Gonatopoulos-Pournatzis

    Article

    Xiao et al Mol Cell. 2024 Jul 11;84(13):2553-2572.e

    Expression

    Mammalian

    Use

    CRISPR and Lentiviral

    Available since

    June 20, 2024

    Availability

    Academic Institutions and Nonprofits only

21. Toronto KnockOut version 3 library (TKOv3)

    Pooled Library

    #90294

    Purpose

    Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

    Depositor

    Jason Moffat

    Article

    Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

    Available since

    May 5, 2017

    Availability

    Academic Institutions and Nonprofits only