375 results

1. Barcode Library 1 (BCL1)

   Pooled Library

   #179852

   Purpose

   Lentiviral barcode library that consists of 10^6 unique barcodes. Barcodes consist of 12bp degenerate region followed by two stable bases (C or G) and 4bp unique library code CCAA.

   Depositor

   Jason Moffat

   Article

   Rehman et al Cell. 2021 Jan 7;184(1):226-242.e21. doi

   Expression

   Mammalian

   Use

   Lentiviral

   Available since

   May 12, 2022

   Availability

   Academic Institutions and Nonprofits only

2. mCRISPRa-v2, Unassigned (m7), top 5 sgRNAs/gene

   Pooled Library

   #84004

   Purpose

   Mouse CRISPRa Pooled Library targeting unassigned genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Jan. 12, 2017

   Availability

   Academic Institutions and Nonprofits only

3. CRISPRi non-coding library (CRiNCL) - Unique to HEK293T

   Pooled Library

   #86543

   Depositor

   Jonathan Weissman

   Article

   Liu et al Science. 2017 Jan 06. Vol. 355, Issue 63

   Available since

   March 8, 2017

   Availability

   Academic Institutions and Nonprofits only

4. hCRISPRi-v2, Stress and Proteostasis (h3), top 5 sgRNAs/gene

   Pooled Library

   #83973

   Purpose

   Human CRISPRi Pooled Library targeting stress and proteostasis genes

   Depositor

   Jonathan Weissman

   Article

   Horlbeck et al Elife. 2016 Sep 23;5. pii: e19760. doi:

   Available since

   Dec. 14, 2016

   Availability

   Academic Institutions and Nonprofits only

5. SARS-CoV-2 RBD Wuhan-Hu-1 SSM Library

   Pooled Library

   #1000000182

   Depositor

   Jesse Bloom

   Available since

   June 14, 2022

   Availability

   Academic Institutions and Nonprofits only

6. mTF-CRISPRai

   Pooled Library

   #122131

   Purpose

   Expresses gRNAs for mouse transcription factor-CRISPR activation

   Depositor

   Stanley Qi

   Article

   Liu et al Cell Stem Cell. 2018 Sep 28. pii: S1934-

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available since

   April 25, 2019

   Availability

   Academic Institutions and Nonprofits only

7. sgRNA pool for Streptococcus pneumoniae

   Pooled Library

   #170432

   Purpose

   CRISPR library targeting S. pneumoniae D39V

   Depositor

   Jan-Willem Veening

   Article

   Liu et al Cell Host Microbe. 2021 Jan 13;29(1):107

   Expression

   Bacterial

   Use

   CRISPR

   Available since

   Aug. 31, 2021

   Availability

   Academic Institutions and Nonprofits only

8. pCMV-Rep78/68 Scanning Saturation Mutagenesis (SSM)

   Pooled Library

   #198050

   Purpose

   By supplying an AAV cap gene of interest in trans, researchers can use this library to investigate the effects of rep mutations on production of a wide range of AAV capsid serotypes

   Depositor

   George Church

   Article

   Jain et al bioRxiv 2023.01.31.526541

   Expression

   Mammalian

   Use

   AAV

   Available since

   May 4, 2023

   Availability

   Academic Institutions and Nonprofits only

9. PYR1 Double Mutant Library

   Pooled Library

   #1000000181

   Depositor

   Timothy Whitehead

   Available since

   June 21, 2022

   Availability

   Academic Institutions and Nonprofits only

10. Pan-Druggable Cancer Library

    Pooled Library

    #182133

    Purpose

    All-in-one CRISPR/Cas system with 74 individual elements. 63 elements target cancer-related genes with FDA-approved drug treatments, and 3 elements target key medulloblastoma driver genes.

    Depositor

    Prashant Mali

    Article

    Hu et al Biomaterials. 2022 Jan;280:121276. doi:

    Species

    Homo sapiens

    Use

    CRISPR and Lentiviral

    Available since

    Aug. 26, 2022

    Availability

    Academic Institutions and Nonprofits only