384 results

1. Human Epigenetic Knockout Library

   Pooled Library

   #162256

   Purpose

   Lentiviral CRISPR library targets human epigenetic genes

   Depositor

   Kivanc Birsoy

   Article

   Williams et al Cell Metab. 2020 Apr 7;31(4):852-861.e6.

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   Nov. 17, 2020

   Availability

   Academic Institutions and Nonprofits only

2. Mouse sgRNA library Brie in lentiGuide-Puro

   Pooled Library

   #73633

   Purpose

   Mouse sgRNA library in backbone lentiGuide-Puro containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Has Service

   Lentiviral Prep

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

3. Human GeCKO Lentiviral sgRNA Library v2 (lentiGuide-Puro)

   Pooled Library

   #1000000049

   Purpose

   CRISPR gRNA knockout pooled library for targeting the human genome

   Depositor

   Feng Zhang

   Available Since

   May 8, 2014

   Availability

   Academic Institutions and Nonprofits only

4. Mouse sgRNA library Brie in lentiCRISPRv2

   Pooled Library

   #73632

   Purpose

   Mouse sgRNA library in backbone lentiCRISPRv2 containing 78,637 unique sgRNAs targeting 19,674 genes along with 1000 non-targeting controls

   Depositor

   David Root, John Doench

   Article

   Doench et al Nat Biotechnol. 2016 Jan 18. doi: 10.103

   Expression

   Mammalian

   Use

   CRISPR and Lentiviral

   Available Since

   Feb. 25, 2016

   Availability

   Academic Institutions and Nonprofits only

5. pMSCV-U6gRNA(lib)-PGKpuroT2ABFP library

   Pooled Library

   #104861

   Depositor

   Sarah Teichmann

   Article

   Henriksson et al Cell. 2019 Jan 7. pii: S0092-8674(18)315

   Available Since

   Sept. 9, 2019

   Availability

   Academic Institutions and Nonprofits only

6. Julianna (split-vector)

   Pooled Library

   #247028

   Purpose

   Mouse genome-wide CRISPR knockout library for the use of S. pyogenes Cas9. Each gene is targeted by 3 constructs.

   Depositor

   David Root, John Doench

   Article

   Drepanos et al bioRxiv 2025.08.26.672375; doi: https://

   Expression

   Mammalian

   Species

   Mus musculus

   Use

   CRISPR and Lentiviral

   Available Since

   Oct. 2, 2025

   Availability

   Academic Institutions and Nonprofits only

7. Toronto KnockOut version 3 library (TKOv3)

   Pooled Library

   #90294

   Purpose

   Optimized library offering improved accuracy, efficiency, and scalability for CRISPR screens compared to TKOv1

   Depositor

   Jason Moffat

   Article

   Hart et al G3 (Bethesda). 2017 Aug 7;7(8):2719-2727

   Available Since

   May 5, 2017

   Availability

   Academic Institutions and Nonprofits only

8. MinLibCas9

   Pooled Library

   #164896

   Purpose

   Human genome-wide CRISPR-Cas9 gRNA library, optimised by mining existing large-scale screening datasets, which provides a >60% reduction in size while preserving key information content

   Depositor

   Mathew Garnett

   Article

   Gonçalves et al Genome Biol. 2021 Jan 21;22(1):40. doi:

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   CRISPR and Lentiviral

   Available Since

   May 20, 2021

   Availability

   Academic Institutions and Nonprofits only

9. MORF library without GFP and mCherry controls

   Pooled Library

   #192821

   Purpose

   Barcoded transcription factor ORF library for high throughput screening

   Depositor

   Feng Zhang

   Article

   Joung et al Cell. 2023 Jan 5;186(1):209-229.e26. doi

   Expression

   Mammalian

   Species

   Homo sapiens

   Use

   Lentiviral

   Available Since

   Jan. 11, 2023

   Availability

   Academic Institutions and Nonprofits only

10. Human CRISPRa sgRNA library Calabrese in backbone XPR_502 (P65 HSF)

    Pooled Library

    #1000000111

    Purpose

    Genome-wide CRISPR gRNA pooled library for activation of human genes

    Depositor

    David Root, John Doench

    Available Since

    Aug. 3, 2017

    Availability

    Academic Institutions and Nonprofits only